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J. Kalervo Hiltunen

J. Kalervo Hiltunen

D-Index & Metrics

Biology and Biochemistry

D-Index
63
Citations
10901
World Ranking
10460
National Ranking
74

Overview

J. Kalervo Hiltunen is affiliated with the University of Oulu in Finland. Their research primarily focuses on the fields of Biochemistry, Genetics and Molecular Biology, with a total of 16 publications attributed to these areas. Within these main fields, their work extends into several subfields including Molecular Biology, Biochemistry, Clinical Biochemistry, Public Health, Environmental and Occupational Health, and Materials Chemistry.

The main topics addressed in their research include Biochemical Acid Research Studies, Mitochondrial Function and Pathology, Microbial Metabolic Engineering and Bioproduction, Metabolism and Genetic Disorders, Enzyme Structure and Function, as well as Pregnancy-related Medical Research and Reproductive Health and Contraception.

The scientist has collaborated frequently with several co-authors, among them:

  • Alexander J. Kastaniotis (5 co-authored works)
  • Mahbubur Rahman (3 co-authored works)
  • Laura P. Pietikäinen (2 co-authored works)
  • Carol L. Dieckmann (2 co-authored works)
  • M. Kristian Koski (2 co-authored works)

J. Kalervo Hiltunen's publications have appeared in multiple venues, including:

  • Acta Crystallographica Section D Structural Biology (2 publications)
  • BMC Biology (1 publication)
  • The Journal of Clinical Endocrinology & Metabolism (1 publication)
  • Nature Communications (1 publication)
  • bioRxiv (Cold Spring Harbor Laboratory) (1 publication)

Selected recent papers by Hiltunen include:

  • Genetic dissection of the mitochondrial lipoylation pathway in yeast, 2021, BMC Biology
  • Estradiol Valerate in COC Has More Favorable Inflammatory Profile Than Synthetic Ethinyl Estradiol: A Randomized Trial, 2020, The Journal of Clinical Endocrinology & Metabolism
  • An engineered variant of MECR reductase reveals indispensability of long-chain acyl-ACPs for mitochondrial respiration, 2023, Nature Communications
  • Expression and analysis of the SAM-dependent RNA methyltransferase Rsm22 from Saccharomyces cerevisiae, 2021, Acta Crystallographica Section D Structural Biology
  • Crystallographic binding studies of rat peroxisomal multifunctional enzyme type 1 with 3-ketodecanoyl-CoA: capturing active and inactive states of its hydratase and dehydrogenase catalytic sites, 2020, Acta Crystallographica Section D Structural Biology

This profile indicates a consistent engagement with mitochondrial biochemistry and molecular enzymology, alongside research addressing metabolic functions and their pathological implications. The involvement in clinical biochemistry topics and related reproductive health research also highlights a multidisciplinary approach within the biochemical sciences.

Best Publications

  • Peroxisomal β-oxidation—A metabolic pathway with multiple functions

    Yves Poirier;Vasily D. Antonenkov;Tuomo Glumoff;J. Kalervo Hiltunen

  • The biochemistry of peroxisomal β-oxidation in the yeast Saccharomyces cerevisiae

    J.Kalervo Hiltunen;Anu M. Mursula;Hanspeter Rottensteiner;Rik K. Wierenga

  • Saturated Very-Long-Chain Fatty Acids Promote Cotton Fiber and Arabidopsis Cell Elongation by Activating Ethylene Biosynthesis

    Yong-Mei Qin;Chun-Yang Hu;Yu Pang;Alexander J. Kastaniotis

  • Peroxisomal multifunctional beta-oxidation protein of Saccharomyces cerevisiae. Molecular analysis of the fox2 gene and gene product.

    J K Hiltunen;B Wenzel;A Beyer;R Erdmann

  • Peroxisomes are oxidative organelles.

    Vasily D. Antonenkov;Silke Grunau;Steffen Ohlmeier;J. Kalervo Hiltunen

  • Crystal structure of enoyl-coenzyme A (CoA) hydratase at 2.5 angstroms resolution: a spiral fold defines the CoA-binding pocket.

    C K Engel;M Mathieu;J P Zeelen;J K Hiltunen

  • Mitochondrial Fatty Acid Synthesis Type II: More than Just Fatty Acids

    J. Kalervo Hiltunen;Melissa S. Schonauer;Kaija J. Autio;Telsa M. Mittelmeier

  • The yeast mitochondrial proteome, a study of fermentative and respiratory growth

    Steffen Ohlmeier;Alexander J. Kastaniotis;J. Kalervo Hiltunen;Ulrich Bergmann

  • Transfer of metabolites across the peroxisomal membrane

    Vasily D. Antonenkov;J. Kalervo Hiltunen

  • Pxmp2 Is a Channel-Forming Protein in Mammalian Peroxisomal Membrane

    Aare Rokka;Aare Rokka;Vasily D. Antonenkov;Vasily D. Antonenkov;Raija Soininen;Hanna L. Immonen

  • beta-Oxidation of polyunsaturated fatty acids by rat liver peroxisomes. A role for 2,4-dienoyl-coenzyme A reductase in peroxisomal beta-oxidation.

    J K Hiltunen;T Kärki;I E Hassinen;H Osmundsen

  • Mitochondrial fatty acid synthesis and respiration.

    J. Kalervo Hiltunen;Kaija J. Autio;Kaija J. Autio;Melissa S. Schonauer;Melissa S. Schonauer;V.A. Samuli Kursu;V.A. Samuli Kursu

  • Enhanced polyamine catabolism alters homeostatic control of white adipose tissue mass, energy expenditure, and glucose metabolism.

    Eija Pirinen;Teemu Kuulasmaa;Marko Pietilä;Sami Heikkinen

  • Apicoplast and endoplasmic reticulum cooperate in fatty acid biosynthesis in apicomplexan parasite Toxoplasma gondii.

    Srinivasan Ramakrishnan;Melissa D. Docampo;James I. MacRae;François M. Pujol

  • Lipoic acid synthesis and attachment in yeast mitochondria.

    Melissa S. Schonauer;Alexander J. Kastaniotis;V. A. Samuli Kursu;J. Kalervo Hiltunen

  • Mitochondrial fatty acid synthesis, fatty acids and mitochondrial physiology

    Alexander J. Kastaniotis;Kaija J. Autio;Juha M. Kerätär;Geoffray Monteuuis

  • Dithiothreitol-capped fluorescent gold nanoclusters: an efficient probe for detection of copper(II) ions in aqueous solution.

    Han Ding;Chunsu Liang;Kangbo Sun;Hui Wang

  • The crystal structure of enoyl-CoA hydratase complexed with octanoyl-CoA reveals the structural adaptations required for binding of a long chain fatty acid-CoA molecule.

    C.K. Engel;T.R. Kiema;J.K. Hiltunen;R.K. Wierenga

  • The rat liver peroxisomal membrane forms a permeability barrier for cofactors but not for small metabolites in vitro

    Vasily D. Antonenkov;Raija T. Sormunen;J. Kalervo Hiltunen

  • The crystal structure of dienoyl-CoA isomerase at 1.5 å resolution reveals the importance of aspartate and glutamate sidechains for catalysis

    Yorgo Modis;Sirpa A Filppula;Dmitri K Novikov;Brian Norledge

Frequent Co-Authors

Rik K. Wierenga
Rik K. Wierenga University of Oulu
Ilmo E. Hassinen
Ilmo E. Hassinen University of Oulu
Raija Sormunen
Raija Sormunen University of Oulu
Yves Poirier
Yves Poirier University of Lausanne
Ralf Erdmann
Ralf Erdmann Ruhr University Bochum
Yu-Xian Zhu
Yu-Xian Zhu Wuhan University
Myriam Baes
Myriam Baes KU Leuven
Thomas Kietzmann
Thomas Kietzmann University of Oulu
Rolf K. Berge
Rolf K. Berge University of Bergen
Ian W. Dawes
Ian W. Dawes University of New South Wales

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