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Biology and Biochemistry

D-Index
50
Citations
8115
World Ranking
17718
National Ranking
1396

Overview

Nikita Gamper is affiliated with the University of Leeds in the United Kingdom. Their research spans several interconnected fields within biomedical science, prominently focusing on neuroscience, biochemistry, genetics, molecular biology, and medicine. The subfields of their work include molecular biology, cellular and molecular neuroscience, physiology, sensory systems, and cardiology and cardiovascular medicine.

The primary research themes addressed by Gamper cover pain mechanisms and treatments, neuroscience and neuropharmacology research, ion channel regulation and function, cardiac electrophysiology and arrhythmias, ion channels and receptors, neurobiology and insect physiology research, and trace elements in health.

Key recent publications by Gamper include:

  • Dorsal root ganglia control nociceptive input to the central nervous system (2023), published in PLoS Biology
  • Activation of parabrachial nucleus - ventral tegmental area pathway underlies the comorbid depression in chronic neuropathic pain in mice (2021), published in Cell Reports
  • Local Ca 2+ signals couple activation of TRPV1 and ANO1 sensory ion channels (2020), published in Science Signaling
  • Kv7 Channels and Excitability Disorders (2021), published in Handbook of Experimental Pharmacology
  • Junctophilin-4 facilitates inflammatory signalling at plasma membrane-endoplasmic reticulum junctions in sensory neurons (2021), published in The Journal of Physiology

Frequent co-authors often collaborating with Gamper include:

  • Shihab Shah
  • Frederick Jones
  • Xiaona Du
  • Pierce Mullen
  • Hailin Zhang

Gamper's publications are prominently featured in several specialized venues, including:

  • Biophysical Journal
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • Cell Reports
  • Journal of Biological Chemistry

In addition to articles, Gamper has contributed to academic books, including a publication with Springer Science+Business Media titled Pharmacology of Potassium Channels in 2021.

Best Publications

  • The acute nociceptive signals induced by bradykinin in rat sensory neurons are mediated by inhibition of M-type K+ channels and activation of Ca2+-activated Cl– channels

    Boyi Liu;John E. Linley;Xiaona Du;Xuan Zhang

  • Cell volume in the regulation of cell proliferation and apoptotic cell death.

    Florian Lang;Markus Ritter;Nikita Gamper;Stephan Huber

  • Regulation of Kv7 (KCNQ) K+ Channel Open Probability by Phosphatidylinositol 4,5-Bisphosphate

    Yang Li;Nikita Gamper;Donald W. Hilgemann;Mark S. Shapiro

  • Regulation of ion transport proteins by membrane phosphoinositides.

    Nikita Gamper;Mark S. Shapiro

  • Calmodulin mediates Ca2+-dependent modulation of M-type K+ channels.

    Nikita Gamper;Mark S. Shapiro

  • Phosphotidylinositol 4,5-Bisphosphate Signals Underlie Receptor-Specific Gq/11-Mediated Modulation of N-Type Ca2+ Channels

    Nikita Gamper;Vitaliy Reznikov;Yoichi Yamada;Jian Yang

  • Activation of the Cl− Channel ANO1 by Localized Calcium Signals in Nociceptive Sensory Neurons Requires Coupling with the IP3 Receptor

    Xin Jin;Xin Jin;Shihab Shah;Yani Liu;Huiran Zhang

  • Plasmodium falciparum activates endogenous Cl− channels of human erythrocytes by membrane oxidation

    Stephan M. Huber;Anne-Catrin Uhlemann;Nikita L. Gamper;Christophe Duranton

  • Chloride conductance and volume-regulatory nonselective cation conductance in human red blood cell ghosts.

    Stephan M. Huber;Nikita Gamper;Florian Lang

  • Local GABAergic signaling within sensory ganglia controls peripheral nociceptive transmission

    Xiaona Du;Han Hao;Yuehui Yang;Sha Huang

  • The cannabinoid WIN 55,212-2 inhibits transient receptor potential vanilloid 1 (TRPV1) and evokes peripheral antihyperalgesia via calcineurin

    Amol M. Patwardhan;Nathaniel A. Jeske;Theodore J. Price;Nikita Gamper

  • Understanding inflammatory pain: ion channels contributing to acute and chronic nociception

    John E. Linley;Kirstin Rose;Lezanne Ooi;Nikita Gamper

  • Bradykinin-Induced Functional Competence and Trafficking of the δ-Opioid Receptor in Trigeminal Nociceptors

    Amol M. Patwardhan;Kelly A Berg;Armen N. Akopain;Nathaniel Aaron Jeske

  • Cannabinoid WIN 55,212-2 Regulates TRPV1 Phosphorylation in Sensory Neurons

    Nathaniel Aaron Jeske;Amol M. Patwardhan;Nikita Gamper;Theodore J. Price

  • Structural requirements for differential sensitivity of KCNQ K+ channels to modulation by Ca2+/calmodulin.

    Nikita Gamper;Yang Li;Mark S. Shapiro

  • IGF-1 up-regulates K+ channels via PI3-kinase, PDK1 and SGK1.

    Gamper N;Fillon S;Huber Sm;Feng Y

  • Transcriptional repression of the M channel subunit Kv7.2 in chronic nerve injury

    Kirstin Rose;Lezanne Ooi;Carine Dalle;Carine Dalle;Brian Robertson

  • Control of somatic membrane potential in nociceptive neurons and its implications for peripheral nociceptive transmission.

    Xiaona Du;Han Hao;Sylvain Gigout;Dongyang Huang

  • Potassium channels in peripheral pain pathways: expression, function and therapeutic potential.

    Xiaona Du;Nikita Gamper

  • Oxidative modification of M-type K+ channels as a mechanism of cytoprotective neuronal silencing

    Nikita Gamper;Nikita Gamper;Oleg Zaika;Yang Li;Pamela Martin

Frequent Co-Authors

Chris Peers
Chris Peers University of Leeds
Florian Lang
Florian Lang University of Tübingen
Stephan M. Huber
Stephan M. Huber University of Tübingen
James D. Stockand
James D. Stockand The University of Texas Health Science Center at San Antonio
David J. Beech
David J. Beech University of Leeds
Stephen A. Baldwin
Stephen A. Baldwin University of Leeds
Philip Cohen
Philip Cohen University of Dundee
Armen N. Akopian
Armen N. Akopian The University of Texas Health Science Center at San Antonio
Stefan Bröer
Stefan Bröer Australian National University
Carsten A. Wagner
Carsten A. Wagner University of Zurich

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