World's Best Scientists 2026 revealed!

D-Index & Metrics

Neuroscience

D-Index
54
Citations
13059
World Ranking
4870
National Ranking
2196

Overview

Armen N. Akopian is affiliated with The University of Texas Health Science Center at San Antonio in the United States. Their research predominantly focuses on medicine and neuroscience, with significant contributions in subfields such as physiology, cellular and molecular neuroscience, neurology, psychiatry and mental health, and complementary and manual therapy.

The scientist's work covers a variety of main topics, including:

  • Pain Mechanisms and Treatments
  • Neuropeptides and Animal Physiology
  • Temporomandibular Joint Disorders
  • Vestibular and Auditory Disorders
  • Stress Responses and Cortisol
  • Olfactory and Sensory Function Studies
  • Migraine and Headache Studies

Akopian has published extensively, with frequent contributions to venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Scientific Reports
  • eNeuro
  • Frontiers in Pain Research
  • Physiology

The scientist has collaborated frequently with peers including Jennifer Mecklenburg, Theodore J. Price, Gregory Dussor, Anahit H. Hovhannisyan, and Zhao Lai.

Recent selected papers by Armen N. Akopian include:

  • "Repetitive stress in mice causes migraine-like behaviors and calcitonin gene-related peptide-dependent hyperalgesic priming to a migraine trigger," 2020, Pain
  • "Transcriptomic sex differences in sensory neuronal populations of mice," 2020, Scientific Reports
  • "Meningeal CGRP -Prolactin Interaction Evokes Female-Specific Migraine Behavior," 2021, Annals of Neurology
  • "Prolactin signaling modulates stress-induced behavioral responses in a preclinical mouse model of migraine," 2021, Headache The Journal of Head and Face Pain
  • "The prolactin receptor long isoform regulates nociceptor sensitization and opioid-induced hyperalgesia selectively in females," 2020, Science Translational Medicine

Best Publications

  • A tetrodotoxin-resistant voltage-gated sodium channel expressed by sensory neurons

    Armen N. Akopian;Lucia Sivilotti;John N. Wood

  • A P2X purinoceptor expressed by a subset of sensory neurons

    Chih Cheng Chen;Armen N. Akopian;Lucia Sivilotti;David Colquhoun

  • The tetrodotoxin-resistant sodium channel SNS has a specialized function in pain pathways

    Armen N. Akopian;Veronika Souslova;Steven England;Steven England;Kenji Okuse

  • A sensory neuron-specific, proton-gated ion channel

    Chih Cheng Chen;Steven England;Armen N. Akopian;John N. Wood

  • Warm-coding deficits and aberrant inflammatory pain in mice lacking P2X3 receptors.

    Veronika Souslova;Paolo Cesare;Yanning Ding;Armen N. Akopian

  • A novel persistent tetrodotoxin-resistant sodium current in SNS-null and wild-type small primary sensory neurons.

    Theodore R. Cummins;Sulayman D. Dib-Hajj;Joel A. Black;Armen N. Akopian

  • LPS sensitizes TRPV1 via activation of TLR4 in trigeminal sensory neurons

    Anibal R. Diogenes;C. C R Ferraz;Armen N. Akopian;Michael A Henry

  • Transient receptor potential TRPA1 channel desensitization in sensory neurons is agonist dependent and regulated by TRPV1-directed internalization

    Armen N. Akopian;Nikita B. Ruparel;Nathaniel A. Jeske;Kenneth M. Hargreaves

  • Heat generates oxidized linoleic acid metabolites that activate TRPV1 and produce pain in rodents

    Amol M. Patwardhan;Armen N. Akopian;Nikita B. Ruparel;Anibal R. Diogenes

  • A new member of the acid-sensing ion channel family.

    Armen N. Akopian;Chih Cheng Chen;Yanning Ding;Paolo Cesare

  • TRPA1-mediated responses in trigeminal sensory neurons: interaction between TRPA1 and TRPV1.

    Margaux M. Salas;Kenneth M. Hargreaves;Armen N. Akopian

  • Activation of TRPV1 in the spinal cord by oxidized linoleic acid metabolites contributes to inflammatory hyperalgesia

    Amol M. Patwardhan;Phoebe E. Scotland;Armen N. Akopian;Kenneth M. Hargreaves

  • Contribution of TRPV1-TRPA1 Interaction to the Single Channel Properties of the TRPA1 Channel

    Alexander Staruschenko;Nathaniel Aaron Jeske;Armen N. Akopian

  • Dural Calcitonin Gene-Related Peptide Produces Female-Specific Responses in Rodent Migraine Models

    Amanda Avona;Carolina Burgos-Vega;Michael D. Burton;Armen N. Akopian

  • Regulation of Expression of the Sensory Neuron-Specific Sodium Channel SNS in Inflammatory and Neuropathic Pain

    Kenji Okuse;Sandra R. Chaplan;Stephen B. McMahon;Z.David Luo

  • NGF Up-regulates TRPA1: Implications for Orofacial Pain

    Anibal R. Diogenes;Armen N. Akopian;Kenneth M Hargreaves

  • The cannabinoid WIN 55,212-2 inhibits transient receptor potential vanilloid 1 (TRPV1) and evokes peripheral antihyperalgesia via calcineurin

    Amol M. Patwardhan;Nathaniel A. Jeske;Theodore J. Price;Nikita Gamper

  • Tmem100 is a regulator of TRPA1-TRPV1 complex and contributes to persistent pain

    Hao Jui Weng;Hao Jui Weng;Kush N. Patel;Nathaniel A. Jeske;Sonya M. Bierbower

  • Cannabinoid WIN 55,212-2 Regulates TRPV1 Phosphorylation in Sensory Neurons

    Nathaniel Aaron Jeske;Amol M. Patwardhan;Nikita Gamper;Theodore J. Price

  • Cannabinoids Desensitize Capsaicin and Mustard Oil Responses in Sensory Neurons via TRPA1 Activation

    Armen N. Akopian;Nikita B. Ruparel;Amol Patwardhan;Kenneth M. Hargreaves

  • A-Kinase Anchoring Protein Mediates TRPV1 Thermal Hyperalgesia through PKA Phosphorylation of TRPV1

    Nathaniel Aaron Jeske;Anibal R. Diogenes;Nikita B. Ruparel;Jill C. Fehrenbacher

Frequent Co-Authors

John Wood
John Wood University College London
Theodore J. Price
Theodore J. Price The University of Texas at Dallas
Gregory Dussor
Gregory Dussor The University of Texas at Dallas
David R. Grattan
David R. Grattan University of Otago
Sulayman D. Dib-Hajj
Sulayman D. Dib-Hajj Yale University
Stephen G. Waxman
Stephen G. Waxman Yale University
Howard L. Fields
Howard L. Fields University of California, San Francisco
Bradley J. Kerr
Bradley J. Kerr University of Alberta
Rajesh Khanna
Rajesh Khanna University of Florida
Annette C. Dolphin
Annette C. Dolphin University College London

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