World's Best Scientists 2026 revealed!
David R. Grattan

David R. Grattan

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Neuroscience
New Zealand
2026

D-Index & Metrics

Neuroscience

D-Index
66
Citations
12225
World Ranking
3050
National Ranking
9

Research.com Recognitions

  • 2026 - Research.com Neuroscience in New Zealand Leader Award
  • 2025 - Research.com Neuroscience in New Zealand Leader Award

Overview

David R. Grattan is affiliated with the University of Otago in New Zealand and has contributed extensively to the fields of medicine and neuroscience. Their research covers a diverse range of topics concentrated mainly on neuroendocrine mechanisms, reproductive medicine, and behavioral neuroscience.

Their recent notable publications include:

  • A Neuro-hormonal Circuit for Paternal Behavior Controlled by a Hypothalamic Network Oscillation (2020, Cell)
  • Reformulation of PULSAR for Analysis of Pulsatile LH Secretion and a Revised Model of Estrogen-Negative Feedback in Mice (2021, Endocrinology)
  • Neuroendocrine Mechanisms Governing Sex Differences in Hyperalgesic Priming Involve Prolactin Receptor Sensory Neuron Signaling (2020, Journal of Neuroscience)
  • Neurophysiological and cognitive changes in pregnancy (2020, Handbook of clinical neurology)
  • Unexpected Plasma Gonadal Steroid and Prolactin Levels Across the Mouse Estrous Cycle (2023, Endocrinology)

The scientist's work frequently appears in a number of publication venues, with the most common being the Journal of Neuroendocrinology, followed by bioRxiv (Cold Spring Harbor Laboratory), Endocrinology, Journal of the Endocrine Society, and Journal of Neuroscience.

David R. Grattan's main research fields are Medicine and Neuroscience. Within these fields, the subfields of focus include:

  • Reproductive Medicine
  • Social Psychology
  • Endocrinology, Diabetes and Metabolism
  • Endocrine and Autonomic Systems
  • Behavioral Neuroscience

Their work centrally addresses topics such as:

  • Hypothalamic control of reproductive hormones
  • Neuroendocrine regulation and behavior
  • Growth Hormone and Insulin-like Growth Factors
  • Stress Responses and Cortisol
  • Regulation of Appetite and Obesity
  • Birth, Development, and Health
  • Neurogenesis and neuroplasticity mechanisms

Throughout their career, David R. Grattan has collaborated frequently with several researchers, including Sharon R. Ladyman, Rosemary S. E. Brown, Zin Khant Aung, Allan E. Herbison, and Eleni C.R. Hackwell. These collaborations have contributed to a steady output of research articles reflecting interdisciplinary engagement within neuroendocrinology and related fields.

Best Publications

  • Leptin Indirectly Regulates Gonadotropin-Releasing Hormone Neuronal Function

    Janette H. Quennell;Alicia C. Mulligan;Alexander Tups;Xinhuai Liu

  • 60 YEARS OF NEUROENDOCRINOLOGY: The hypothalamo-prolactin axis

    David R Grattan

  • Prolactin: a pleiotropic neuroendocrine hormone.

    D. R. Grattan;I. C. Kokay

  • Leptin Deficiency and Diet-Induced Obesity Reduce Hypothalamic Kisspeptin Expression in Mice

    Janette H. Quennell;Christopher S. Howell;Juan Roa;Rachael A. Augustine

  • STAT5b is required for GH-induced liver IGF-I gene expression.

    Helen W. Davey;Tao Xie;Tao Xie;Michael J. McLachlan;Richard J. Wilkins

  • The actions of prolactin in the brain during pregnancy and lactation.

    David R. Grattan

  • Prolactin-induced mitogenesis in the subventricular zone of the maternal brain during early pregnancy is essential for normal postpartum behavioral responses in the mother.

    Caroline M. Larsen;David R. Grattan

  • Region-Specific Reduction in Leptin-Induced Phosphorylation of Signal Transducer and Activator of Transcription-3 (STAT3) in the Rat Hypothalamus Is Associated with Leptin Resistance during Pregnancy

    S. R. Ladyman;D. R. Grattan

  • Hormone interactions regulating energy balance during pregnancy.

    S. R. Ladyman;R. A. Augustine;D. R. Grattan

  • Prolactin action in the medial preoptic area is necessary for postpartum maternal nursing behavior.

    Rosemary S. E. Brown;Mari Aoki;Sharon R. Ladyman;Hollian R. Phillipps

  • Identification of prolactin-sensitive GABA and kisspeptin neurons in regions of the rat hypothalamus involved in the control of fertility.

    Ilona C. Kokay;Sandra L. Petersen;David R. Grattan

  • Prolactin regulation of gonadotropin-releasing hormone neurons to suppress luteinizing hormone secretion in mice.

    David R. Grattan;Christine L. Jasoni;Xinhuai Liu;Greg M. Anderson

  • Prolactin, neurogenesis, and maternal behaviors.

    C.M. Larsen;D.R. Grattan

  • Leptin Rapidly Improves Glucose Homeostasis in Obese Mice by Increasing Hypothalamic Insulin Sensitivity

    Christiane Koch;Rachael A. Augustine;Juliane Steger;Goutham K. Ganjam

  • Obesity During Pregnancy Disrupts Placental Morphology, Cell Proliferation, and Inflammation in a Sex-Specific Manner Across Gestation in the Mouse

    Dong Won Kim;Sarah L. Young;David R. Grattan;Christine L. Jasoni

  • Pregnancy-Induced Adaptation in the Neuroendocrine Control of Prolactin Secretion

    David R. Grattan;Frederik J. Steyn;Ilona C. Kokay;Greg M. Anderson

  • Distribution of prolactin-responsive neurons in the mouse forebrain.

    Rosemary S.E. Brown;Ilona C. Kokay;Allan E. Herbison;David R. Grattan

  • Behavioural significance of prolactin signalling in the central nervous system during pregnancy and lactation

    David R Grattan

  • From feeding one to feeding many: hormone-induced changes in bodyweight homeostasis during pregnancy

    Rachael A. Augustine;Sharon R. Ladyman;David R. Grattan

  • Suppression of leptin receptor messenger ribonucleic acid and leptin responsiveness in the ventromedial nucleus of the hypothalamus during pregnancy in the rat.

    S. R. Ladyman;D. R. Grattan

Frequent Co-Authors

Allan E. Herbison
Allan E. Herbison University of Cambridge
Andrea C. Gore
Andrea C. Gore The University of Texas at Austin
Armen N. Akopian
Armen N. Akopian The University of Texas Health Science Center at San Antonio
Randy J. Nelson
Randy J. Nelson West Virginia University
Patrick R. Hof
Patrick R. Hof Icahn School of Medicine at Mount Sinai
Zuoxin Wang
Zuoxin Wang Florida State University
Theodore J. Price
Theodore J. Price The University of Texas at Dallas
Margaret M. McCarthy
Margaret M. McCarthy University of Maryland, Baltimore
Gregory Dussor
Gregory Dussor The University of Texas at Dallas
Daniel E. Weeks
Daniel E. Weeks University of Pittsburgh

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