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Neuroscience

D-Index
61
Citations
11686
World Ranking
3710
National Ranking
50

Overview

Nai-Hong Chen is affiliated with Peking Union Medical College Hospital in China. Their research spans multiple areas within biochemistry, genetics, molecular biology, neuroscience, and medicine, with a specific focus on molecular biology, neurology, pharmacology, physiology, and immunology.

The topics Nai-Hong Chen has extensively worked on include:

  • Neuroinflammation and Neurodegeneration Mechanisms
  • Connexins and lens biology
  • Ginseng Biological Effects and Applications
  • Parkinson's Disease Mechanisms and Treatments
  • Tryptophan and brain disorders
  • Stress Responses and Cortisol
  • Autophagy in Disease and Therapy

The scientist has published numerous papers in frequent venues, including:

  • Acta Pharmacologica Sinica
  • International Immunopharmacology
  • European Journal of Pharmacology
  • Journal of Ethnopharmacology
  • Frontiers in Pharmacology

Among recent publications authored or co-authored by Nai-Hong Chen are:

  • Anticancer property of ginsenoside Rh2 from ginseng, 2020, European Journal of Medicinal Chemistry
  • Targeting oxidative stress as a preventive and therapeutic approach for cardiovascular disease, 2023, Journal of Translational Medicine
  • Paeoniflorin: A neuroprotective monoterpenoid glycoside with promising anti-depressive properties, 2021, Phytomedicine
  • The receptor hypothesis and the pathogenesis of depression: Genetic bases and biological correlates, 2021, Pharmacological Research
  • Ginsenoside Rg1 prevent and treat inflammatory diseases: A review, 2020, International Immunopharmacology

Frequent co-authors associated with Nai-Hong Chen include:

  • Shifeng Chu
  • Zhen-Zhen Wang
  • Zhao Zhang
  • Qidi Ai
  • Songwei Yang

Best Publications

  • Gap Junction Dysfunction in the Prefrontal Cortex Induces Depressive-Like Behaviors in Rats

    Jian-Dong Sun;Yan Liu;Yu-He Yuan;Jing Li

  • A Narrative Review of Cancer-Related Fatigue (CRF) and Its Possible Pathogenesis.

    Songwei Yang;Shifeng Chu;Shifeng Chu;Yan Gao;Qidi Ai;Qidi Ai

  • Reassessment of subacute MPTP-treated mice as animal model of Parkinson's disease.

    Qiu-shuang Zhang;Yang Heng;Zheng Mou;Ju-yang Huang

  • Selective modulation of microglia polarization to M2 phenotype for stroke treatment.

    Cong-Yuan Xia;Shuai Zhang;Yan Gao;Zhen-Zhen Wang

  • Mitochondria autophagy is induced after hypoxic/ischemic stress in a Drp1 dependent manner: the role of inhibition of Drp1 in ischemic brain damage.

    Wei Zuo;Shuai Zhang;Cong-Yuan Xia;Xiao-Feng Guo

  • Ginsenoside Rg1 protects against ischemic/reperfusion-induced neuronal injury through miR-144/Nrf2/ARE pathway.

    Shi-feng Chu;Zhao Zhang;Xin Zhou;Wen-bin He;Wen-bin He

  • Pathological α-synuclein exacerbates the progression of Parkinson's disease through microglial activation.

    Qiu-Shuang Zhang;Yang Heng;Yu-He Yuan;Nai-Hong Chen;Nai-Hong Chen

  • Research progress on adenosine in central nervous system diseases.

    Ying-Jiao Liu;Ying-Jiao Liu;Jiao Chen;Xun Li;Xin Zhou

  • Protection of PC12 cells from hydrogen peroxide-induced cytotoxicity by salvianolic acid B, a new compound isolated from Radix Salviae miltiorrhizae.

    Chang-Suo Liu;Nai-Hong Chen;Jun-Tian Zhang

  • Osthole improves chronic cerebral hypoperfusion induced cognitive deficits and neuronal damage in hippocampus.

    Hai-Jie Ji;Jin-Feng Hu;Yong-Hui Wang;Xiao-Yu Chen

  • Dynamin-related protein 1: A protein critical for mitochondrial fission, mitophagy, and neuronal death in Parkinson's disease.

    Si-Tong Feng;Zhen-Zhen Wang;Yu-He Yuan;Xiao-Le Wang

  • Nrf2 pathway activation contributes to anti-fibrosis effects of ginsenoside Rg1 in a rat model of alcohol- and CCl4-induced hepatic fibrosis

    Jian-ping Li;Yan Gao;Shi-feng Chu;Zhao Zhang

  • Ginsenoside Rg1 attenuates okadaic acid induced spatial memory impairment by the GSK3β/tau signaling pathway and the Aβ formation prevention in rats.

    Xiu-Yun Song;Jin-Feng Hu;Shi-Feng Chu;Zhao Zhang

  • The molecular mechanism of rotenone-induced α-synuclein aggregation: emphasizing the role of the calcium/GSK3β pathway.

    Yu-he Yuan;Wen-fen Yan;Jian-dong Sun;Ju-yang Huang

  • Improvement of memory in mice and increase of hippocampal excitability in rats by ginsenoside Rg1's metabolites ginsenoside Rh1 and protopanaxatriol.

    Yu-Zhu Wang;Ji Chen;Shi-Feng Chu;Yong-Sheng Wang

  • Research progress in stroke-induced immunodepression syndrome (SIDS) and stroke-associated pneumonia (SAP).

    Dan-Dan Liu;Shi-Feng Chu;Chen Chen;Peng-Fei Yang

  • Protopanaxtriol protects against 3-nitropropionic acid-induced oxidative stress in a rat model of Huntington's disease.

    Yan Gao;Shi-feng Chu;Jian-ping Li;Zhao Zhang

  • The role of chemokines and chemokine receptors in multiple sclerosis.

    Li-Yuan Cui;Shi-Feng Chu;Nai-Hong Chen

  • Ginsenoside Rg1 attenuates motor impairment and neuroinflammation in the MPTP-probenecid-induced parkinsonism mouse model by targeting α-synuclein abnormalities in the substantia nigra.

    Yang Heng;Qiu-Shuang Zhang;Zheng Mu;Jin-Feng Hu

  • Anti-inflammatory function of ginsenoside Rg1 on alcoholic hepatitis through glucocorticoid receptor related nuclear factor-kappa B pathway

    Yan Gao;Shifeng Chu;Jingwei Li;Jianping Li

  • Ginsenoside Rb1 promotes neurotransmitter release by modulating phosphorylation of synapsins through a cAMP-dependent protein kinase pathway.

    Jian-Fei Xue;Zhi-Jun Liu;Jin-Feng Hu;Hong Chen

  • Antioxidant activities of ginsenoside Rg1 against cisplatin-induced hepatic injury through Nrf2 signaling pathway in mice.

    Yan Gao;Shifeng Chu;Qianhang Shao;Meijin Zhang

  • Triterpenoid saponins with neuroprotective effects from the roots of Polygala tenuifolia.

    Chuangjun Li;Jingzhi Yang;Shishan Yu;Naihong Chen

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