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Neuroscience

D-Index
47
Citations
7469
World Ranking
6487
National Ranking
43

Overview

Jose Donato is affiliated with Universidade de São Paulo in Brazil and conducts research primarily in the fields of Medicine and Neuroscience. Their work is extensively focused on endocrine and metabolic processes, with significant contributions to subfields including Endocrine and Autonomic Systems, Physiology, Endocrinology, Diabetes and Metabolism, Molecular Biology, and Epidemiology.

The main topics of their research include:

  • Regulation of Appetite and Obesity
  • Growth Hormone and Insulin-like Growth Factors
  • Adipose Tissue and Metabolism
  • Adipokines, Inflammation, and Metabolic Diseases
  • Hypothalamic control of reproductive hormones
  • Biochemical Analysis and Sensing Techniques
  • Diet and metabolism studies

Jose Donato has published numerous papers, many of which appear in frequent publication venues such as Endocrinology, Life Sciences, Neuroscience Letters, bioRxiv (Cold Spring Harbor Laboratory), and the International Journal of Molecular Sciences. Notable recent papers include:

  • Pro-inflammatory interleukin-6 signaling links cognitive impairments and peripheral metabolic alterations in Alzheimer's disease, 2021, Translational Psychiatry
  • Central Regulation of Metabolism by Growth Hormone, 2021, Cells
  • Characterization of the metabolic differences between male and female C57BL/6 mice, 2022, Life Sciences
  • Short-term exposure to air pollution (PM2.5) induces hypothalamic inflammation, and long-term leads to leptin resistance and obesity via Tlr4/Ikbke in mice, 2020, Scientific Reports
  • Tyrosine Hydroxylase Neurons Regulate Growth Hormone Secretion via Short-Loop Negative Feedback, 2020, Journal of Neuroscience

Their collaborative efforts include frequent coauthors such as Frederick Wasinski, Renata Frazão, John J. Kopchick, Edward O. List, and Mariana Tavares. These collaborations reflect sustained joint research activity contributing broadly to the endocrinology and neuroscience disciplines.

Best Publications

  • Direct leptin action on POMC neurons regulates glucose homeostasis and hepatic insulin sensitivity in mice

    Eric D. Berglund;Claudia R. Vianna;Jose Donato;Mi Hwa Kim

  • Leptin's effect on puberty in mice is relayed by the ventral premammillary nucleus and does not require signaling in Kiss1 neurons.

    José Donato Jr.;José Donato Jr.;Roberta Mascioli Cravo;Renata Frazão;Laurent Gautron

  • Characterization of Kiss1 neurons using transgenic mouse models

    Roberta M. Cravo;Lisandra O. Margatho;Lisandra O. Margatho;Sherri Osborne-Lawrence;José Donato

  • Pro-inflammatory interleukin-6 signaling links cognitive impairments and peripheral metabolic alterations in Alzheimer's disease.

    Natalia M. Lyra e Silva;Natalia M. Lyra e Silva;Rafaella A. Gonçalves;Rafaella A. Gonçalves;Rafaella A. Gonçalves;Tharick A. Pascoal;Ricardo A. S. Lima-Filho

  • Steroidogenic factor 1 directs programs regulating diet-induced thermogenesis and leptin action in the ventral medial hypothalamic nucleus

    Ki Woo Kim;Liping Zhao;Jose Donato;Daisuke Kohno

  • Growth hormone regulates neuroendocrine responses to weight loss via AgRP neurons.

    Isadora C. Furigo;Pryscila D. S. Teixeira;Gabriel O. de Souza;Gisele C. L. Couto

  • Hypothalamic Sites of Leptin Action Linking Metabolism and Reproduction

    José Donato;Roberta M. Cravo;Renata Frazão;Carol F. Elias

  • Effects of leucine supplementation on the body composition and protein status of rats submitted to food restriction

    Jose Donato;Rogerio Graça Pedrosa;Vinicius Fernandes Cruzat;Ivanir Santana de Oliveira Pires

  • Reviewing the Effects of l-Leucine Supplementation in the Regulation of Food Intake, Energy Balance, and Glucose Homeostasis

    João A.B. Pedroso;Thais T. Zampieri;Jose Donato

  • The Ventral Premammillary Nucleus Links Fasting-Induced Changes in Leptin Levels and Coordinated Luteinizing Hormone Secretion

    Jose Donato;Renata J. Silva;Luciane V. Sita;Syann Lee

  • The role of leptin in health and disease.

    Angela M. Ramos-Lobo;Jose Donato

  • FOXO1 in the ventromedial hypothalamus regulates energy balance

    Ki Woo Kim;Jose Donato;Eric D. Berglund;Yun Hee Choi

  • Lateral habenula and the rostromedial tegmental nucleus innervate neurochemically distinct subdivisions of the dorsal raphe nucleus in the rat.

    Chemutai Sego;Luciano Gonçalves;Leandro Lima;Isadora Clivatti Furigo

  • Inactivation of SOCS3 in leptin receptor-expressing cells protects mice from diet-induced insulin resistance but does not prevent obesity

    João A.B. Pedroso;Daniella C. Buonfiglio;Lais I. Cardinali;Isadora C. Furigo

  • Chronic sleep restriction promotes brain inflammation and synapse loss, and potentiates memory impairment induced by amyloid-β oligomers in mice.

    Grasielle C. Kincheski;Isabela S. Valentim;Julia R. Clarke;Danielle Cozachenco

  • Oral supplementations with free and dipeptide forms of L-glutamine in endotoxemic mice: effects on muscle glutamine-glutathione axis and heat shock proteins.

    Vinicius F. Cruzat;Vinicius F. Cruzat;Lucas C. Pantaleão;José Donato;Paulo Ivo Homem de Bittencourt

  • Leucine supplementation improves adiponectin and total cholesterol concentrations despite the lack of changes in adiposity or glucose homeostasis in rats previously exposed to a high-fat diet.

    Francisco L. Torres-Leal;Miriam H. Fonseca-Alaniz;Gabriela F. R. Teodoro;Mariana D. de Capitani

  • Shift in Kiss1 cell activity requires estrogen receptor

    Renata Frazão;Renata Frazão;Roberta M. Cravo;Jose Donato;Dhirender V. Ratra

  • Possible crosstalk between leptin and prolactin during pregnancy.

    V.S. Nagaishi;L.I. Cardinali;T.T. Zampieri;I.C. Furigo

  • SOCS3 as a future target to treat metabolic disorders

    João A.B. Pedroso;Angela M. Ramos-Lobo;Jose Donato

  • The Acute Effects of Leptin Require PI3K Signaling in the Hypothalamic Ventral Premammillary Nucleus

    Kevin W. Williams;Jong Woo Sohn;Jose Donato;Charlotte E. Lee

  • Chemical identity and connections of medial preoptic area neurons expressing melanin-concentrating hormone during lactation.

    Tatiane Araujo Rondini;José Donato;Bruno de Crudis Rodrigues;Jackson Cioni Bittencourt

Frequent Co-Authors

Jackson C. Bittencourt
Jackson C. Bittencourt Universidade de São Paulo
Fernanda G. De Felice
Fernanda G. De Felice Queen's University
Laurent Gautron
Laurent Gautron The University of Texas Southwestern Medical Center
Sergio T. Ferreira
Sergio T. Ferreira Federal University of Rio de Janeiro
Newton S. Canteras
Newton S. Canteras Universidade de São Paulo
Yoichi Ueta
Yoichi Ueta University of Occupational and Environmental Health Japan
Todd Charlton Sacktor
Todd Charlton Sacktor SUNY Downstate Medical Center
Pedro Rosa-Neto
Pedro Rosa-Neto McGill University
Vania F. Prado
Vania F. Prado University of Western Ontario
Antônio Lúcio Teixeira
Antônio Lúcio Teixeira The University of Texas Health Science Center at San Antonio

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