D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 65 Citations 12,471 261 World Ranking 6020 National Ranking 459

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Internal medicine
  • Biochemistry

His scientific interests lie mostly in Cell biology, Internal medicine, Endocrinology, Voltage-dependent calcium channel and Transient receptor potential channel. David J. Beech has researched Cell biology in several fields, including TRPC1, TRPC Cation Channels and T-type calcium channel. Internal medicine is closely attributed to Endothelial stem cell in his work.

His Voltage-dependent calcium channel study integrates concerns from other disciplines, such as Biophysics and Calcium channel. The Biophysics study combines topics in areas such as Muscarinic acetylcholine receptor and Patch clamp. His Transient receptor potential channel study deals with the bigger picture of Biochemistry.

His most cited work include:

  • Piezo1 integration of vascular architecture with physiological force (428 citations)
  • TrpC1 Is a Membrane-Spanning Subunit of Store-Operated Ca2+ Channels in Native Vascular Smooth Muscle Cells (326 citations)
  • Non-selective cationic channels of smooth muscle and the mammalian homologues of Drosophila TRP (222 citations)

What are the main themes of his work throughout his whole career to date?

David J. Beech spends much of his time researching Cell biology, Internal medicine, Biophysics, Endocrinology and Transient receptor potential channel. David J. Beech interconnects Endothelial stem cell, Calcium, Vascular smooth muscle, PIEZO1 and T-type calcium channel in the investigation of issues within Cell biology. His research on Internal medicine often connects related areas such as Cardiology.

In his research on the topic of Biophysics, Intracellular is strongly related with Extracellular. His research on Transient receptor potential channel frequently links to adjacent areas such as Ion channel. His research in TRPC5 tackles topics such as Calcium channel which are related to areas like TRPM3.

He most often published in these fields:

  • Cell biology (34.63%)
  • Internal medicine (30.74%)
  • Biophysics (25.29%)

What were the highlights of his more recent work (between 2017-2021)?

  • PIEZO1 (11.67%)
  • Biophysics (25.29%)
  • Cell biology (34.63%)

In recent papers he was focusing on the following fields of study:

The scientist’s investigation covers issues in PIEZO1, Biophysics, Cell biology, TRPC5 and Internal medicine. His Biophysics study incorporates themes from Dehydrated hereditary stomatocytosis and Ion channel. His Cell biology research incorporates themes from Weibel–Palade body, Endothelium and Vascular smooth muscle.

As part of the same scientific family, David J. Beech usually focuses on Vascular smooth muscle, concentrating on STIM1 and intersecting with Calcium channel. His TRPC5 research is under the purview of TRPC1. The various areas that David J. Beech examines in his Internal medicine study include Endocrinology and Cardiology.

Between 2017 and 2021, his most popular works were:

  • Force Sensing by Piezo Channels in Cardiovascular Health and Disease. (41 citations)
  • Yoda1 analogue (Dooku1) which antagonizes Yoda1-evoked activation of Piezo1 and aortic relaxation. (37 citations)
  • Activation of TRPC1 Channel by Metabotropic Glutamate Receptor mGluR5 Modulates Synaptic Plasticity and Spatial Working Memory. (26 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Internal medicine
  • Biochemistry

David J. Beech mainly focuses on TRPC5, Biophysics, TRPC4, PIEZO1 and Ion channel. His TRPC5 study introduces a deeper knowledge of TRPC1. The concepts of his Biophysics study are interwoven with issues in Agonist, HEK 293 cells and TRPC.

His TRPC4 research entails a greater understanding of Transient receptor potential channel. His work on TRPC3 as part of general Transient receptor potential channel research is often related to Cancer cell, thus linking different fields of science. His PIEZO1 study combines topics in areas such as Vasoconstriction, Endothelium, Neuroscience and Cell biology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Piezo1 integration of vascular architecture with physiological force

Jing Li;Bing Hou;Sarka Tumova;Katsuhiko Muraki.
Nature (2014)

697 Citations

TrpC1 Is a Membrane-Spanning Subunit of Store-Operated Ca2+ Channels in Native Vascular Smooth Muscle Cells

Shang-Zhong Xu;David J. Beech.
Circulation Research (2001)

370 Citations

Non-selective cationic channels of smooth muscle and the mammalian homologues of Drosophila TRP

D. J. Beech;K. Muraki;R. Flemming.
The Journal of Physiology (2004)

339 Citations

TRPC channel activation by extracellular thioredoxin

Shang Zhong Xu;Piruthivi Sukumar;Fanning Zeng;Jing Li.
Nature (2008)

302 Citations

K channel activation by nucleotide diphosphates and its inhibition by glibenclamide in vascular smooth muscle cells.

D.J. Beech;H. Zhang;K. Nakao;T.B. Bolton.
British Journal of Pharmacology (1993)

285 Citations

A diffusible second messenger mediates one of the pathways coupling receptors to calcium channels in rat sympathetic neurons.

Laurent Bernheim;David J. Beech;Bertil Hille.
Neuron (1991)

285 Citations

Block of TRPC5 channels by 2-aminoethoxydiphenyl borate : a differential, extracellular and voltage-dependent effect

Shang-Zhong Xu;Fanning Zeng;Guylain Boulay;Christian Grimm.
British Journal of Pharmacology (2005)

279 Citations

Critical Intracellular Ca2+ Dependence of Transient Receptor Potential Melastatin 2 (TRPM2) Cation Channel Activation

Damian McHugh;Richard Flemming;Shang-Zhong Xu;Anne-Laure Perraud.
Journal of Biological Chemistry (2003)

266 Citations

Pertussis toxin and voltage dependence distinguish multiple pathways modulating calcium channels of rat sympathetic neurons

David J. Beech;Laurent Bernheim;Bertil Hille.
Neuron (1992)

259 Citations

Upregulated TRPC1 Channel in Vascular Injury In Vivo and Its Role in Human Neointimal Hyperplasia

B. Kumar;K. Dreja;S.S. Shah;A. Cheong.
Circulation Research (2006)

229 Citations

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