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Sreenivasan Ponnambalam

Sreenivasan Ponnambalam

D-Index & Metrics

Biology and Biochemistry

D-Index
51
Citations
6908
World Ranking
17364
National Ranking
1363

Overview

Sreenivasan Ponnambalam is affiliated with the University of Leeds in the United Kingdom and has contributed extensively to fields intersecting Biochemistry, Genetics and Molecular Biology, as well as Medicine. Their research output comprises 33 publications in Biochemistry, Genetics and Molecular Biology and 25 in Medicine, reflecting a broad engagement with molecular and clinical sciences.

The scientist's subfields of study prominently include Molecular Biology, Cancer Research, Immunology, Oncology, and Pulmonary and Respiratory Medicine. Their work frequently addresses topics critical to understanding disease mechanisms and therapeutic targets, such as Angiogenesis and VEGF in Cancer, Blood properties and coagulation, Cancer, Hypoxia, and Metabolism, Blood Coagulation and Thrombosis Mechanisms, Atherosclerosis and Cardiovascular Diseases, Cancer-related molecular mechanisms, and Cancer, Lipids, and Metabolism.

Several recent publications demonstrate the diversity and focus of their research. These include:

  • Structural Basis for Vascular Endothelial Growth Factor Receptor Activation and Implications for Disease Therapy, 2020, Biomolecules
  • TDO2 modulates liver cancer cell migration and invasion via the Wnt5a pathway, 2022, International Journal of Oncology
  • Fibrinogen interaction with complement C3: a potential therapeutic target to reduce thrombosis risk, 2020, Haematologica
  • Scavenger Receptors as Biomarkers and Therapeutic Targets in Cardiovascular Disease, 2020, Cells
  • Prognostic value of members of NFAT family for pan-cancer and a prediction model based on NFAT2 in bladder cancer, 2021, Aging

Ponnambalam has published multiple times in notable journals including Aging, Journal of Cell Science, Journal of Biomolecular Structure and Dynamics, Methods in Molecular Biology, and Biomolecules. This range indicates continued engagement with both fundamental molecular biology and clinical biomolecular research.

Frequent collaborators in their research include Michael A. Harrison, Dhananjay Jade, Shervanthi Homer-Vanniasinkam, Darren C. Tomlinson, and William R. Critchley. Each of these co-authors has contributed to multiple projects with Ponnambalam, suggesting sustained collaborative relationships in research endeavors.

Best Publications

  • Biochemistry and cell biology of mammalian scavenger receptors

    Jane E. Murphy;Philip R. Tedbury;Shervanthi Homer-Vanniasinkam;John H. Walker

  • Scavenger Receptor Structure and Function in Health and Disease

    Izma Abdul Zani;Sam L. Stephen;Nadeem A. Mughal;David Russell

  • Intrinsic tyrosine kinase activity is required for vascular endothelial growth factor receptor 2 ubiquitination, sorting and degradation in endothelial cells.

    Lorna C. Ewan;Helen M. Jopling;Haiyan Jia;Shweta Mittar

  • Affimer proteins are versatile and renewable affinity reagents

    Christian Tiede;Robert Bedford;Sophie J Heseltine;Gina Smith

  • The lectin-like oxidized low-density-lipoprotein receptor: a pro-inflammatory factor in vascular disease.

    Sarah Dunn;Ravinder S. Vohra;Jane E. Murphy;Shervanthi Homer-Vanniasinkam

  • The TGN38 glycoprotein contains two non-overlapping signals that mediate localization to the trans-Golgi network.

    S Ponnambalam;C Rabouille;J P Luzio;T Nilsson

  • Ligand-Stimulated VEGFR2 Signaling is Regulated by Co-Ordinated Trafficking and Proteolysis

    Alexander F. Bruns;Shane P. Herbert;Adam F. Odell;Helen M. Jopling

  • TGN38 and its orthologues: roles in post-TGN vesicle formation and maintenance of TGN morphology

    George Banting;S Ponnambalam

  • Clathrin light chains: arrays of protein motifs that regulate coated-vesicle dynamics.

    Frances M. Brodsky;Beth L. Hill;Susan L. Acton;Inke Näthke

  • Distinct compartmentalization of TGN46 and beta 1,4-galactosyltransferase in HeLa cells.

    Alan R. Prescott;John M. Lucocq;John James;Jane M. Lister

  • Scavenger Receptors and Their Potential as Therapeutic Targets in the Treatment of Cardiovascular Disease

    Sam L. Stephen;Katie Freestone;Sarah Dunn;Michael W. Twigg;Michael W. Twigg

  • Primate homologues of rat TGN38: primary structure, expression and functional implications

    Sreenivasan Ponnambalam;Milena Girotti;Marie Laure Yaspo;Charles E. Owen

  • LOX-1 scavenger receptor mediates calcium-dependent recognition of phosphatidylserine and apoptotic cells

    Jane E. Murphy;Daryl Tacon;Philip R. Tedbury;Jonathan M. Hadden

  • A Golgi Localization Signal Identified in the Menkes Recombinant Protein

    Michael J. Francis;Emma E. Jones;Elaine R. Levy;Sreenivasan Ponnambalam

  • Constitutive protein secretion from the trans-Golgi network to the plasma membrane.

    Sreenivasan Ponnambalam;Stephen A Baldwin

  • Transcription initiation at the Escherichia coli galactose operon promoters in the absence of the normal -35 region sequences.

    S Ponnambalam;C Webster;A Bingham;S Busby

  • Conservation and diversity in families of coated vesicle adaptins.

    S Ponnambalam;M S Robinson;A P Jackson;L Peiperl

  • Identification of a di-leucine motif within the C terminus domain of the Menkes disease protein that mediates endocytosis from the plasma membrane.

    Michael J. Francis;Emma E. Jones;Elaine R. Levy;Rowena L. Martin

  • Atherosclerosis and the Lectin-like OXidized Low-Density Lipoprotein Scavenger Receptor

    Ravinder S. Vohra;Jane E. Murphy;John H. Walker;Sreenivasan Ponnambalam

  • Author response: Affimer proteins are versatile and renewable affinity reagents

    Christian Tiede;Robert Bedford;Sophie J Heseltine;Gina Smith

Frequent Co-Authors

Ian Zachary
Ian Zachary University College London
Anthony P. Monaco
Anthony P. Monaco Tufts University
John M. Lucocq
John M. Lucocq University of St Andrews
Michael J. McPherson
Michael J. McPherson University of Leeds
Alan R. Prescott
Alan R. Prescott University of Dundee
Monica Hollstein
Monica Hollstein University of Leeds
Stephen J. W. Busby
Stephen J. W. Busby University of Birmingham
Miriam Wittmann
Miriam Wittmann University of Leeds
David J. Beech
David J. Beech University of Leeds
Peter Parham
Peter Parham Stanford University

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