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Immunology

D-Index
49
Citations
6758
World Ranking
4370
National Ranking
377

Overview

Miriam Wittmann is affiliated with the University of Leeds in the United Kingdom. Their research primarily spans the fields of Medicine and Immunology and Microbiology, with a publication record that includes 72 works in Medicine and 30 in Immunology and Microbiology. Subfields of their research include Immunology, Dermatology, Rheumatology, Epidemiology, and Physiology.

The scientist's work covers key topics such as Dermatology and Skin Diseases, Systemic Lupus Erythematosus Research, Psoriasis: Treatment and Pathogenesis, T-cell and B-cell Immunology, Contact Dermatitis and Allergies, IL-33, ST2, and ILC Pathways, as well as Atherosclerosis and Cardiovascular Diseases.

Frequent publication venues reflect the focus of their research, including:

  • Journal of Investigative Dermatology
  • Annals of the Rheumatic Diseases
  • Lara D. Veeken
  • British Journal of Dermatology
  • Frontiers in Immunology

Notable recent papers authored or co-authored by Miriam Wittmann include:

  • "Functionally impaired plasmacytoid dendritic cells and non-haematopoietic sources of type I interferon characterize human autoimmunity" (2020, Nature Communications)
  • "Emerging concepts of type I interferons in SLE pathogenesis and therapy" (2022, Nature Reviews Rheumatology)
  • "T Helper 2 IL-4/IL-13 Dual Blockade with Dupilumab Is Linked to Some Emergent T Helper 17-Type Diseases, Including Seronegative Arthritis and Enthesitis/Enthesopathy, but Not to Humoral Autoimmune Diseases" (2022, Journal of Investigative Dermatology)
  • "Normal human enthesis harbours conventional CD4+ and CD8+ T cells with regulatory features and inducible IL-17A and TNF expression" (2020, Annals of the Rheumatic Diseases)
  • "TNF-α Regulates Human Plasmacytoid Dendritic Cells by Suppressing IFN-α Production and Enhancing T Cell Activation" (2021, The Journal of Immunology)

Miriam Wittmann frequently collaborates with several co-authors who have contributed extensively alongside them. These include Edward M Vital, Dennis McGonagle, Charlie Bridgewood, Adewonuola Alase, and Md Yuzaiful Md Yusof.

Best Publications

  • Histamine H4 receptor stimulation suppresses IL-12p70 production and mediates chemotaxis in human monocyte-derived dendritic cells.

    Ralf Gutzmer;Carola Diestel;Susanne Mommert;Brigitta Köther

  • IL-36γ (IL-1F9) is a biomarker for psoriasis skin lesions.

    Angelo Massimiliano D'Erme;Angelo Massimiliano D'Erme;Dagmar Wilsmann-Theis;Julia Wagenpfeil;Michael Hölzel

  • Birch pollen-related foods trigger atopic dermatitis in patients with specific cutaneous T-cell responses to birch pollen antigens.

    Renate Reekers;Marc Busche;Miriam Wittmann;Alexander Kapp

  • Severe atopic dermatitis is associated with sensitization to staphylococcal enterotoxin B (SEB).

    K. Breuer;M. Wittmann;B. Bösche;A. Kapp

  • Ultrasonographic Assessment of Nail in Psoriatic Disease Shows a Link between Onychopathy and Distal Interphalangeal Joint Extensor Tendon Enthesopathy

    Sibel Zehra Aydin;Concepción Castillo-Gallego;Zoe R Ash;Helena Marzo-Ortega

  • Activated Human T Lymphocytes Express a Functional C3a Receptor

    Thomas Werfel;Konstanze Kirchhoff;Miriam Wittmann;Gabriele Begemann

  • Cathepsin S is the major activator of the psoriasis-associated proinflammatory cytokine IL-36γ.

    Joseph S. Ainscough;Tom Macleod;Dennis McGonagle;Rosella Brakefield

  • Functionally impaired plasmacytoid dendritic cells and non-haematopoietic sources of type I interferon characterize human autoimmunity

    Antonios Psarras;Antonios Psarras;Antonios Psarras;Adewonuola Alase;Agne Antanaviciute;Ian M Carr

  • Phosphodiesterase 4 Inhibition in the Treatment of Psoriasis, Psoriatic Arthritis and Other Chronic Inflammatory Diseases

    Miriam Wittmann;Miriam Wittmann;Philip S. Helliwell

  • IL-33 impacts on the skin barrier by downregulating the expression of filaggrin

    Jenny Seltmann;Lennart M. Roesner;Friedrich-Wilhelm von Hesler;Miriam Wittmann

  • Human keratinocytes respond to interleukin-18: implication for the course of chronic inflammatory skin diseases.

    Miriam Wittmann;Rahul Purwar;Christina Hartmann;Ralf Gutzmer

  • Tofacitinib for the treatment of psoriasis and psoriatic arthritis.

    Anna Berekmeri;Farrouq Mahmood;Miriam Wittmann;Philip Helliwell

  • Human Dendritic Cells Express the IL-18R and Are Chemoattracted to IL-18

    Ralf Gutzmer;Katja Langer;Susanne Mommert;Miriam Wittmann

  • A novel two-score system for interferon status segregates autoimmune diseases and correlates with clinical features

    Y. M. El-Sherbiny;Y. M. El-Sherbiny;Y. M. El-Sherbiny;A. Psarras;A. Psarras;M. Y. Md Yusof;M. Y. Md Yusof;E. M. A. Hensor;E. M. A. Hensor

  • C5a suppresses the production of IL-12 by IFN-gamma-primed and lipopolysaccharide-challenged human monocytes.

    Miriam Wittmann;Jörg Zwirner;Vivi-Ann Larsson;Konstanze Kirchhoff

  • Prediction of autoimmune connective tissue disease in an at-risk cohort: prognostic value of a novel two-score system for interferon status

    Yuzaiful Md Yusof;Antonios Psarras;Yasser M El-Sherbiny;Elizabeth M A Hensor

  • Brief report: Responses to rituximab suggest B cell-independent inflammation in cutaneous systemic lupus erythematosus

    Edward M. Vital;Miriam Wittmann;Sara Edward;Yuzaiful Md Yusof

  • Identification of myeloid cells in the human enthesis as the main source of local IL-23 production

    Charlie Bridgewood;Abdulla Watad;Tobias Russell;Timothy M Palmer

  • Neutrophil Elastase-mediated proteolysis activates the anti-inflammatory cytokine IL-36 Receptor antagonist

    Tom Macleod;Rosella Doble;Dennis McGonagle;Christopher W. Wasson

  • Heat shock protein 70 (HSP70) induces cytotoxicity of T-helper cells

    Constança Figueiredo;Miriam Wittmann;Dong Wang;Ralf Dressel

  • Alpha-toxin is produced by skin colonizing Staphylococcus aureus and induces a T helper type 1 response in atopic dermatitis.

    K. Breuer;M. Wittmann;K. Kempe;A. Kapp

Frequent Co-Authors

Thomas Werfel
Thomas Werfel Hannover Medical School
Paul Emery
Paul Emery University of Leeds
Dennis McGonagle
Dennis McGonagle University of Leeds
Alexander Kapp
Alexander Kapp Hannover Medical School
Ralf Gutzmer
Ralf Gutzmer Hannover Medical School
Sinisa Savic
Sinisa Savic University of Leeds
George C. Tsokos
George C. Tsokos Harvard Medical School
Michael F. McDermott
Michael F. McDermott University of Leeds
Philip S. Helliwell
Philip S. Helliwell University of Leeds
Michael Kracht
Michael Kracht University of Giessen

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