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Immunology

D-Index
56
Citations
12137
World Ranking
3709
National Ranking
324

Overview

Sinisa Savic is affiliated with the University of Leeds in the United Kingdom and has a research focus centered on Medicine, with a specialization in Immunology, Rheumatology, Genetics, Infectious Diseases, and Molecular Biology. Their scholarly output includes work published extensively in fields related to immune system function, autoimmune disorders, and infectious disease processes.

Their research covers several specific topics, including:

  • Otitis Media and Relapsing Polychondritis
  • Immunodeficiency and Autoimmune Disorders
  • COVID-19 Clinical Research Studies
  • Inflammasome and Immune Disorders
  • Drug-Induced Adverse Reactions
  • SARS-CoV-2 and COVID-19 Research
  • Coagulation, Bradykinin, Polyphosphates, and Angioedema

Savic has contributed to frequent publication venues such as:

  • Journal of Clinical Immunology
  • British Journal of Anaesthesia
  • Journal of Allergy and Clinical Immunology
  • Annals of the Rheumatic Diseases
  • bioRxiv (Cold Spring Harbor Laboratory)

Their recent papers encompass important clinical and molecular research areas, including the following notable publications:

  • Tocilizumab in Hospitalized Patients with Severe Covid-19 Pneumonia (2021) - New England Journal of Medicine
  • Somatic Mutations in UBA1 and Severe Adult-Onset Autoinflammatory Disease (2020) - New England Journal of Medicine
  • COVID-19 in patients with primary and secondary immunodeficiency: The United Kingdom experience (2020) - Journal of Allergy and Clinical Immunology
  • Somatic Mutations in UBA1 Define a Distinct Subset of Relapsing Polychondritis Patients With VEXAS (2021) - Arthritis & Rheumatology
  • Novel somatic mutations in UBA1 as a cause of VEXAS syndrome (2021) - Blood

Frequent collaborators in their research include:

  • James A. Poulter
  • Catherine Cargo
  • Louise Savic
  • Mark Kačar
  • Gururaj Arumugakani

Best Publications

  • Somatic Mutations in UBA1 and Severe Adult-Onset Autoinflammatory Disease.

    David B. Beck;Marcela A. Ferrada;Keith A. Sikora;Amanda K. Ombrello

  • Tocilizumab in Hospitalized Patients with Severe Covid-19 Pneumonia.

    Ivan O Rosas;Norbert Bräu;Norbert Bräu;Michael Waters;Ronaldo C Go

  • Clinical spectrum and features of activated phosphoinositide 3-kinase δ syndrome: A large patient cohort study.

    Tanya I Coulter;Anita Chandra;Chris M Bacon;Judith Babar

  • The Ca2+ sensor STIM1 regulates the type I interferon response by retaining the signaling adaptor STING at the endoplasmic reticulum.

    Sonal Srikanth;Jin Seok Woo;Beibei Wu;Yasser M. El-Sherbiny;Yasser M. El-Sherbiny;Yasser M. El-Sherbiny

  • Familial autoinflammation with neutrophilic dermatosis reveals a regulatory mechanism of pyrin activation

    Seth L. Masters;Seth L. Masters;Vasiliki Lagou;Isabelle Jéru;Isabelle Jéru;Paul J. Baker;Paul J. Baker

  • Clinical and immunologic phenotype associated with activated phosphoinositide 3-kinase δ syndrome 2: A cohort study

    Elodie Elkaim;Elodie Elkaim;Benedicte Neven;Benedicte Neven;Benedicte Neven;Julie Bruneau;Julie Bruneau;Kanako Mitsui-Sekinaka

  • Evidence of NLRP3-inflammasome activation in rheumatoid arthritis (RA); genetic variants within the NLRP3-inflammasome complex in relation to susceptibility to RA and response to anti-TNF treatment

    Rebeccah J Mathews;James I Robinson;James I Robinson;Michele Battellino;Chi Wong;Chi Wong

  • Whole-genome sequencing of a sporadic primary immunodeficiency cohort

    Thaventhiran Jed.;H Lango Allen;O S Burren;W Rae

  • Loss-of-function nuclear factor κB subunit 1 (NFKB1) variants are the most common monogenic cause of common variable immunodeficiency in Europeans

    Paul Tuijnenburg;Hana Lango Allen;Hana Lango Allen;Siobhan O. Burns;Daniel Greene;Daniel Greene

  • COVID-19 in patients with primary and secondary immunodeficiency: The United Kingdom experience.

    Adrian M. Shields;Siobhan O. Burns;Siobhan O. Burns;Sinisa Savic;Alex G. Richter

  • Novel somatic mutations in UBA1 as a cause of VEXAS syndrome

    James A Poulter;Jason Charles Collins;Catherine Cargo;Ruth M de Tute

  • Disease Evolution and Response to Rapamycin in Activated Phosphoinositide 3-Kinase δ Syndrome: The European Society for Immunodeficiencies-Activated Phosphoinositide 3-Kinase δ Syndrome Registry

    Maria Elena Maccari;Hassan Abolhassani;Hassan Abolhassani;Asghar Aghamohammadi;Alessandro Aiuti

  • Histone deacetylases are dysregulated in rheumatoid arthritis and a novel histone deacetylase 3-selective inhibitor reduces interleukin-6 production by peripheral blood mononuclear cells from rheumatoid arthritis patients.

    Justin Gillespie;Sinisa Savic;Chi Wong;Aiden Hempshall

  • British Lung Foundation/United Kingdom Primary Immunodeficiency Network Consensus Statement on the Definition, Diagnosis, and Management of Granulomatous-Lymphocytic Interstitial Lung Disease in Common Variable Immunodeficiency Disorders

    John R. Hurst;Nisha Verma;David Lowe;Helen E. Baxendale

  • Management of suspected immediate perioperative allergic reactions: an international overview and consensus recommendations.

    Lene H. Garvey;Lene H. Garvey;Pascale Dewachter;David L. Hepner;Paul Michel Mertes

  • Late-Onset Cryopyrin-Associated Periodic Syndromes Caused by Somatic NLRP3 Mosaicism-UK Single Center Experience.

    Dorota M. Rowczenio;Sónia Melo Gomes;Juan I. Aróstegui;Anna Mensa-Vilaro

  • Hypomorphic caspase activation and recruitment domain 11 ( CARD11 ) mutations associated with diverse immunologic phenotypes with or without atopic disease

    Batsukh Dorjbal;Jeffrey R Stinson;Chi A Ma;Michael A Weinreich

  • Comparative epidemiology of suspected perioperative hypersensitivity reactions.

    Paul Michel Mertes;Didier G. Ebo;Tomaz Garcez;Michael Rose;Michael Rose

  • Familial Mediterranean fever and related periodic fever syndromes/autoinflammatory diseases.

    Sinisa Savic;Laura J. Dickie;Michele Battellino;Michael F. McDermott

  • 'Warning: Allergic to penicillin': Association between penicillin allergy status in 2.3 million NHS general practice electronic health records, antibiotic prescribing and health outcomes

    R M West;C J Smith;S H Pavitt;C C Butler

  • Autoinflammatory diseases: update on classification diagnosis and management

    Shelly Pathak;Michael F McDermott;Sinisa Savic

  • Tocilizumab in Hospitalized Patients With COVID-19 Pneumonia

    Ivan Rosas;Norbert Bräu;Michael Waters;Ronaldo C. Go

  • Familial Autoinflammation with Neutrophilic Dermatosis Reveals a Novel Regulatory Mechanism of Pyrin Activation

    P. J. Baker;V. Lagou;I. Jeru;L. Van Eyck

Frequent Co-Authors

Michael F. McDermott
Michael F. McDermott University of Galway
Paul Emery
Paul Emery University of Leeds
Siobhan O. Burns
Siobhan O. Burns University College London
Dennis McGonagle
Dennis McGonagle University of Leeds
Jolan E. Walter
Jolan E. Walter University of South Florida
Andrew J. Cant
Andrew J. Cant Newcastle University
Helen J. Lachmann
Helen J. Lachmann University College London
Adrian J. Thrasher
Adrian J. Thrasher University College London
Jonathan Stephens
Jonathan Stephens University of Cambridge
Rainer Doffinger
Rainer Doffinger University of Cambridge

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