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Immunology

D-Index
110
Citations
42093
World Ranking
506
National Ranking
306

Medicine

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110
Citations
42122
World Ranking
5591
National Ranking
3007

Overview

Emma Guttman-Yassky is affiliated with the Icahn School of Medicine at Mount Sinai in the United States. Their research primarily focuses on the field of Medicine, with a significant emphasis on Dermatology, Immunology, Allergy, Physiology, and Rheumatology.

The scientist's main areas of study include:

  • Dermatology and Skin Diseases
  • Allergic Rhinitis and Sensitization
  • Asthma and respiratory diseases
  • Food Allergy and Anaphylaxis Research
  • Urticaria and Related Conditions
  • IL-33, ST2, and ILC Pathways
  • Hair Growth and Disorders

Emma Guttman-Yassky has contributed to numerous publications found predominantly in the following venues:

  • Journal of Investigative Dermatology
  • Journal of the American Academy of Dermatology
  • Allergy
  • Journal of Allergy and Clinical Immunology
  • British Journal of Dermatology

Some of their recent significant papers include:

  • "Tralokinumab for moderate-to-severe atopic dermatitis: results from two 52-week, randomized, double-blind, multicentre, placebo-controlled phase III trials (ECZTRA 1 and ECZTRA 2)*" (2020, British Journal of Dermatology)
  • "Type 2 immunity in the skin and lungs" (2020, Allergy)
  • "Once-daily upadacitinib versus placebo in adolescents and adults with moderate-to-severe atopic dermatitis (Measure Up 1 and Measure Up 2): results from two replicate double-blind, randomised controlled phase 3 trials" (2021, The Lancet)
  • "Single-cell transcriptome analysis of human skin identifies novel fibroblast subpopulation and enrichment of immune subsets in atopic dermatitis" (2020, Journal of Allergy and Clinical Immunology)
  • "Baricitinib in patients with moderate-to-severe atopic dermatitis and inadequate response to topical corticosteroids: results from two randomized monotherapy phase III trials" (2020, British Journal of Dermatology)

Their collaborative network includes frequent co-authorship with:

  • Ester Del Duca
  • Yeriel Estrada
  • Jonathan I. Silverberg
  • James G. Krueger
  • Eric L. Simpson

The broad thematic span of their work engages with immune-related mechanisms, especially within the context of dermatological and allergic diseases. The volume and venues of publication indicate an active role in advancing understanding in areas such as atopic dermatitis, immune system pathways, and related clinical interventions.

Best Publications

  • Two Phase 3 Trials of Dupilumab versus Placebo in Atopic Dermatitis

    Eric L. Simpson;Thomas Bieber;Emma Guttman-Yassky;Lisa A. Beck

  • Dupilumab treatment in adults with moderate-to-severe atopic dermatitis.

    Lisa A. Beck;Diamant Thaçi;Jennifer D. Hamilton;Neil M. Graham

  • Progressive activation of T(H)2/T(H)22 cytokines and selective epidermal proteins characterizes acute and chronic atopic dermatitis.

    Julia K. Gittler;Julia K. Gittler;Avner Shemer;Mayte Suárez-Fariñas;Judilyn Fuentes-Duculan

  • Th17 cytokines interleukin (IL)-17 and IL-22 modulate distinct inflammatory and keratinocyte-response pathways.

    K.E. Nograles;L.C. Zaba;E. Guttman-Yassky;J. Fuentes-Duculan

  • IL-22–producing “T22” T cells account for upregulated IL-22 in atopic dermatitis despite reduced IL-17–producing TH17 T cells

    Kristine E. Nograles;Lisa C. Zaba;Avner Shemer;Judilyn Fuentes-Duculan

  • Integrative Responses to IL-17 and TNF-α in Human Keratinocytes Account for Key Inflammatory Pathogenic Circuits in Psoriasis

    Andrea Chiricozzi;Emma Guttman-Yassky;Emma Guttman-Yassky;Mayte Suárez-Fariñas;Kristine E. Nograles

  • The immunology of atopic dermatitis and its reversibility with broad-spectrum and targeted therapies

    Patrick M. Brunner;Emma Guttman-Yassky;Donald Y.M. Leung

  • Dupilumab progressively improves systemic and cutaneous abnormalities in patients with atopic dermatitis

    Emma Guttman-Yassky;Emma Guttman-Yassky;Robert Bissonnette;Benjamin Ungar;Benjamin Ungar;Mayte Suárez-Fariñas

  • The Asian atopic dermatitis phenotype combines features of atopic dermatitis and psoriasis with increased TH17 polarization.

    Shinji Noda;Mayte Suárez-Fariñas;Benjamin Ungar;Benjamin Ungar;Soo Jung Kim

  • Atopic dermatitis endotypes and implications for targeted therapeutics.

    Tali Czarnowicki;Helen He;James G. Krueger;Emma Guttman-Yassky;Emma Guttman-Yassky

  • Cellular and molecular immunologic mechanisms in patients with atopic dermatitis

    Thomas Werfel;Jean-Pierre Allam;Tilo Biedermann;Kilian Eyerich

  • Tralokinumab for moderate‐to‐severe atopic dermatitis: results from two 52‐week, randomized, double‐blind, multicentre, placebo‐controlled phase III trials (ECZTRA 1 and ECZTRA 2)*

    A. Wollenberg;A. Blauvelt;E. Guttman‐Yassky;M. Worm

  • Deciphering the Complexities of Atopic Dermatitis: Shifting Paradigms in Treatment Approaches

    Donald Y.M. Leung;Emma Guttman-Yassky

  • Type 2 immunity in the skin and lungs.

    Cezmi A. Akdis;Peter D. Arkwright;Marie-Charlotte Brüggen;William Busse

  • Efficacy and Safety of Dupilumab in Adolescents With Uncontrolled Moderate to Severe Atopic Dermatitis: A Phase 3 Randomized Clinical Trial.

    Eric L. Simpson;Amy S. Paller;Elaine C. Siegfried;Mark Boguniewicz

  • Dupilumab improves the molecular signature in skin of patients with moderate-to-severe atopic dermatitis.

    Jennifer D. Hamilton;Mayte Suárez-Fariñas;Nikhil Dhingra;Irma Cardinale

  • Intrinsic atopic dermatitis shows similar TH2 and higher TH17 immune activation compared with extrinsic atopic dermatitis

    Mayte Suárez-Fariñas;Nikhil Dhingra;Nikhil Dhingra;Julia Gittler;Julia Gittler;Avner Shemer

  • Nonlesional atopic dermatitis skin is characterized by broad terminal differentiation defects and variable immune abnormalities.

    Mayte Suárez-Fariñas;Suzanne J. Tintle;Avner Shemer;Andrea Chiricozzi;Andrea Chiricozzi

  • Once-daily upadacitinib versus placebo in adolescents and adults with moderate-to-severe atopic dermatitis (Measure Up 1 and Measure Up 2): results from two replicate double-blind, randomised controlled phase 3 trials

    Emma Guttman-Yassky;Henrique D. Teixeira;Eric L. Simpson;Kim A. Papp

  • Treatment of atopic dermatitis with tralokinumab, an anti-IL-13 mAb.

    Andreas Wollenberg;Michael D. Howell;Emma Guttman-Yassky;Jonathan I. Silverberg

  • Contrasting pathogenesis of atopic dermatitis and psoriasis—Part I: Clinical and pathologic concepts

    Emma Guttman-Yassky;Emma Guttman-Yassky;Kristine E. Nograles;James G. Krueger

Frequent Co-Authors

James G. Krueger
James G. Krueger Rockefeller University
Mayte Suárez-Fariñas
Mayte Suárez-Fariñas Icahn School of Medicine at Mount Sinai
Eric L. Simpson
Eric L. Simpson Oregon Health & Science University
Judilyn Fuentes-Duculan
Judilyn Fuentes-Duculan Rockefeller University
Jonathan I. Silverberg
Jonathan I. Silverberg George Washington University Hospital
Amy S. Paller
Amy S. Paller Northwestern University
Lisa A. Beck
Lisa A. Beck University of Rochester Medical Center
Lawrence F. Eichenfield
Lawrence F. Eichenfield University of California, San Diego
Mark Lebwohl
Mark Lebwohl Icahn School of Medicine at Mount Sinai
Kenji Kabashima
Kenji Kabashima Kyoto University

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