Kenji Yamamoto

Overview

Best Publications

• Genetic Analyses of Proteolysis, Hemoglobin Binding, and Hemagglutination of Porphyromonas gingivalis CONSTRUCTION OF MUTANTS WITH A COMBINATION OF rgpA, rgpB, kgp, AND hagA

  Yixin Shi;Dinath B. Ratnayake;Kuniaki Okamoto;Naoko Abe

  473
  Citations

• Cathepsin D Deficiency Induces Lysosomal Storage with Ceroid Lipofuscin in Mouse CNS Neurons

  Masato Koike;Hiroshi Nakanishi;Paul Saftig;Junji Ezaki

  452
  Citations

• Construction and Characterization of Arginine-specific Cysteine Proteinase (Arg-gingipain)-deficient Mutants of Porphyromonas gingivalis EVIDENCE FOR SIGNIFICANT CONTRIBUTION OF Arg-GINGIPAIN TO VIRULENCE

  Koji Nakayama;Tomoko Kadowaki;Kuniaki Okamoto;Kenji Yamamoto

  349
  Citations

• Age-Related Changes in Activities and Localizations of Cathepsins D, E, B, and L in the Rat Brain Tissues

  Hiroshi Nakanishi;Kazuyoshi Tominaga;Tutomu Amano;Ichirou Hirotsu

  246
  Citations

• Purification and characterization of a novel arginine-specific cysteine proteinase (argingipain) involved in the pathogenesis of periodontal disease from the culture supernatant of Porphyromonas gingivalis.

  T. Kadowaki;M. Yoneda;K. Okamoto;K. Maeda

  243
  Citations

• Characterization of New Fluorogenic Substrates for the Rapid and Sensitive Assay of Cathepsin E and Cathepsin D

  Yoshiyuki Yasuda;Takashi Kageyama;Akifumi Akamine;Masahiro Shibata

  241
  Citations

• Arg-gingipain acts as a major processing enzyme for various cell surface proteins in Porphyromonas gingivalis.

  Tomoko Kadowaki;Koji Nakayama;Fuminobu Yoshimura;Kuniaki Okamoto

  234
  Citations

• Involvement of a lysine-specific cysteine proteinase in hemoglobin adsorption and heme accumulation by Porphyromonas gingivalis

  Kuniaki Okamoto;Koji Nakayama;Tomoko Kadowaki;Naoko Abe

  227
  Citations

• Porphyromonas gingivalis Proteinases as Virulence Determinants in Progression of Periodontal Diseases

  Tomoko Kadowaki;Koji Nakayama;Kuniaki Okamoto;Naoko Abe

  208
  Citations

• Involvement of arginine-specific cysteine proteinase (Arg-gingipain) in fimbriation of Porphyromonas gingivalis.

  Koji Nakayama;Fuminobu Yoshimura;Tomoko Kadowaki;Kenji Yamamoto

  204
  Citations

• Quantitation and immunohistochemical localization of cathepsins E and D in rat tissues and blood cells

  Hideaki Sakai;Takashi Saku;Yuzo Kato;Kenji Yamamoto

  184
  Citations

• Involvement of nitric oxide released from microglia-macrophages in pathological changes of cathepsin D-deficient mice.

  Hiroshi Nakanishi;Jian Zhang;Masato Koike;Tsuyoshi Nishioku

  166
  Citations

• Affinity Purification and Properties of Cathepsin-E-Like Acid Proteinase from Rat Spleen

  Kenji Yamamoto;Nobuo Katsuda;Keitaro Kato

  161
  Citations

• Cloning and sequencing of the gene encoding a novel lysine-specific cysteine proteinase (Lys-gingipain) in Porphyromonas gingivalis: structural relationship with the arginine-specific cysteine proteinase (Arg-gingipain).

  Kuniaki Okamoto;Tomoko Kadowaki;Koji Nakayama;Kenji Yamamoto

  157
  Citations

• Purification, gene cloning, gene expression, and mutants of Dps from the obligate anaerobe Porphyromonas gingivalis.

  Junichi Ueshima;Mikio Shoji;Dinath B. Ratnayake;Kihachiro Abe

  156
  Citations

• Increased Expression of Cathepsins E and D in Neurons of the Aged Rat Brain and Their Colocalization with Lipofuscin and Carboxy‐Terminal Fragments of Alzheimer Amyloid Precursor Protein

  Hiroshi Nakanishi;Tutomu Amano;Dewi Fatma Suniarti Sastradipura;Yoshito Yoshimine

  149
  Citations

• A novel autosomal dominant spinocerebellar ataxia (SCA16) linked to chromosome 8q22.1-24.1

  Y. Miyoshi;Takeshi Yamada;M. Tanimura;T. Taniwaki

  148
  Citations

• Cathepsin D of rat spleen. Affinity purification and properties of two types of cathepsin D.

  Kenji Yamamoto;Nobuo Katsuda;Masaru Himeno;Keitaro Kato

  146
  Citations

• Structural Characterization of Argingipain, a Novel Arginine-Specific Cysteine Proteinase as a Major Periodontal Pathogenic Factor from Porphyromonas gingivalis

  Kuniaki Okamoto;Yoshio Misumi;Tomoko Kadowaki;Masahiro Yoneda

  143
  Citations

• Haemoglobin receptor protein is intragenically encoded by the cysteine proteinase-encoding genes and the haemagglutinin-encoding gene of Porphyromonas gingivalis.

  Koji Nakayama;Dinath B. Ratnayake;Takayuki Tsukuba;Tomoko Kadowaki

  139
  Citations