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Biology and Biochemistry

D-Index
95
Citations
32355
World Ranking
1905
National Ranking
1048

Overview

James Travis was a researcher affiliated with the University of Georgia in the United States. Their work focused primarily on the intersection of mathematics and medicine, with a particular emphasis on statistical methods in clinical trials and Bayesian inference.

Their research contributed to several main fields of study, including:

  • Mathematics
  • Medicine

Within these fields, they explored various subfields such as:

  • Statistics and Probability
  • Endocrinology, Diabetes and Metabolism
  • Management Science and Operations Research
  • Pediatrics, Perinatology and Child Health
  • Cancer Research

Travis's main research topics included:

  • Statistical Methods in Clinical Trials
  • Advanced Causal Inference Techniques
  • Optimal Experimental Design Methods
  • Statistical Methods and Bayesian Inference
  • Pharmaceutical Studies and Practices
  • Diabetes Management and Research
  • Protease and Inhibitor Mechanisms

Their publications appeared frequently in venues such as:

  • Therapeutic Innovation & Regulatory Science
  • Pharmaceutical Statistics
  • Aliso
  • UNC Libraries
  • Journal of Biopharmaceutical Statistics

Among their recent papers were:

  • The Serpins Are an Expanding Superfamily of Structurally Similar but Functionally Diverse Proteins: EVOLUTION, MECHANISM OF INHIBITION, NOVEL FUNCTIONS, AND A REVISED NOMENCLATURE (2021, UNC Libraries)
  • Bayesian Methods in Human Drug and Biological Products Development in CDER and CBER (2022, Therapeutic Innovation & Regulatory Science)
  • Perspectives on informative Bayesian methods in pediatrics (2023, Journal of Biopharmaceutical Statistics)
  • Bayesian Hierarchical Models for Subgroup Analysis (2024, Pharmaceutical Statistics)
  • Bayesian adaptive design for pediatric clinical trials incorporating a community of prior beliefs (2022, BMC Medical Research Methodology)

Throughout their career, James Travis frequently collaborated with several co-authors, including:

  • Mark D. Rothmann
  • Yun Wang
  • Wenda Tu
  • Roberto Crackel
  • Pablo Bonangelino

Best Publications

  • Human plasma proteinase inhibitors

    J Travis;G S Salvesen

  • The serpins are an expanding superfamily of structurally similar but functionally diverse proteins - Evolution, mechanism of inhibition, novel functions, and a revised nomenclature

    Gary A. Silverman;Phillip I. Bird;Robin W. Carrell;Frank C. Church

  • The serpin superfamily of proteinase inhibitors: structure, function, and regulation.

    J Potempa;E Korzus;J Travis

  • Kinetics of association of serine proteinases with native and oxidized alpha-1-proteinase inhibitor and alpha-1-antichymotrypsin.

    K Beatty;J Bieth;J Travis

  • Human leukocyte granule elastase: rapid isolation and characterization

    Robert J. Baugh;James Travis

  • Degradation of Human Antimicrobial Peptide LL-37 by Staphylococcus aureus-Derived Proteinases

    Magdalena Sieprawska-Lupa;Piotr Mydel;Katarzyna Krawczyk;Kinga Wójcik

  • The oxidative inactivation of human alpha-1-proteinase inhibitor. Further evidence for methionine at the reactive center.

    D Johnson;J Travis

  • α1-Antitrypsin and the serpins: variation and countervariation

    Robin Carrell;James Travis

  • Purification, Characterization, and Sequence Analysis of a Potential Virulence Factor from Porphyromonas gingivalis, Peptidylarginine Deiminase

    Walker T. McGraw;Jan Potempa;David Farley;James Travis

  • Isolation of albumin from whole human plasma and fractionation of albumin-depleted plasma

    J Travis;J Bowen;D Tewksbury;D Johnson

  • Rapid conversion of angiotensin I to angiotensin II by neutrophil and mast cell proteinases.

    C F Reilly;D A Tewksbury;N M Schechter;J Travis

  • Selective removal of albumin from plasma by affinity chromatography

    James Travis;Ralph Pannell

  • X-ray crystal structure of the complex of human leukocyte elastase (PMN elastase) and the third domain of the turkey ovomucoid inhibitor.

    W. Bode;An-Zhi Wei;R. Huber;E. Meyer

  • Enzymatic inactivation of human alpha-1-proteinase inhibitor by neutrophil myeloperoxidase.

    N.R. Matheson;P.S. Wong;J. Travis

  • Gingipains, the major cysteine proteinases and virulence factors of Porphyromonas gingivalis: structure, function and assembly of multidomain protein complexes.

    Jan Potempa;Aneta Sroka;Takahisa Imamura;James Travis

  • New method for typing Staphylococcus aureus strains: multiple-locus variable-number tandem repeat analysis of polymorphism and genetic relationships of clinical isolates.

    Artur Sabat;Jolanta Krzyszton-Russjan;Wojciech Strzalka;Renata Filipek

  • Structural evidence for methionine at the reactive site of human alpha-1-proteinase inhibitor.

    D Johnson;J Travis

  • Structure, function, and control of neutrophil proteinases

    James Travis

  • Isolation and properties of human plasma alpha-1-proteinase inhibitor.

    Ralph Pannell;David Johnson;James Travis

  • Purification and characterization of a 50-kDa cysteine proteinase (gingipain) from Porphyromonas gingivalis.

    Z Chen;J Potempa;A Polanowski;M Wikstrom

Frequent Co-Authors

Jan Potempa
Jan Potempa University of Louisville
Robert N. Pike
Robert N. Pike La Trobe University
Guy S. Salvesen
Guy S. Salvesen Sanford Burnham Prebys Medical Discovery Institute
Caroline Attardo Genco
Caroline Attardo Genco Tufts University
James C. Powers
James C. Powers Georgia Institute of Technology
Murray S. Blum
Murray S. Blum University of Georgia
Philip J. Barr
Philip J. Barr BayMedica, Inc.
Stefan Rose-John
Stefan Rose-John Kiel University
Haruhiko Takada
Haruhiko Takada Tohoku University
Peter L. Long
Peter L. Long University of Georgia

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