World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
74
Citations
16645
World Ranking
4807
National Ranking
1506

Biology and Biochemistry

D-Index
74
Citations
17521
World Ranking
5670
National Ranking
2686

Overview

James C. Powers is affiliated with the Georgia Institute of Technology in the United States. They have contributed to the academic community through research and scholarly activities associated with this institution.

While specific details about recent publications, co-authors, or fields of study are not documented, Powers' professional profile highlights their participation in the academic environment of a notable technological university.

There are no listed recent papers, which suggests either a focus on other scholarly activities or that publication records are not currently available.

Similarly, information regarding frequent co-authors, venues of publication, or book publications is not provided, indicating limited publicly available data about collaborations or contributions to edited volumes and books.

Their documented profile does not specify particular fields or subfields of study, which means that an analysis of main research topics or disciplinary focuses cannot be developed from existing records.

No awards or recognitions are recorded, reflecting either an absence of publicly noted honors or that such details are not included in the available data.

James C. Powers is currently active and not deceased, which may suggest ongoing engagement in academic or professional activities.

Best Publications

  • Irreversible inhibitors of serine, cysteine, and threonine proteases.

    James C. Powers;Juliana L. Asgian;Özlem Dogan Ekici;Karen Ellis James

  • Purification of three cytotoxic lymphocyte granule serine proteases that induce apoptosis through distinct substrate and target cell interactions.

    Lianfa Shi;Chih-Min Kam;J. C. Powers;R. Aebersold

  • Human leukocyte and porcine pancreatic elastase: X-ray crystal structures, mechanism, substrate specificity, and mechanism-based inhibitors.

    Wolfram Bode;Edgar Meyer;James C. Powers

  • Mapping the extended substrate binding site of cathepsin G and human leukocyte elastase. Studies with peptide substrates related to the alpha 1-protease inhibitor reactive site.

    Unknown

  • Sensitive substrates for human leukocyte and porcine pancreatic elastase: A study of the merits of various chromophoric and fluorogenic leaving groups in assays for serine proteases

    Mario J. Castillo;Kiichiro Nakajima;Morris Zimmerman;James C. Powers

  • Human and murine cytotoxic T lymphocyte serine proteases: subsite mapping with peptide thioester substrates and inhibition of enzyme activity and cytolysis by isocoumarins.

    Shinjiro Odake;Chih Min Kam;Lakshmi Narasimhan;Martin Poe

  • Reaction of serine proteases with substituted isocoumarins: discovery of 3,4-dichloroisocoumarin, a new general mechanism based serine protease inhibitor.

    Harper Jw;Hemmi K;Powers Jc

  • Identification of proteases that regulate erythrocyte rupture by the malaria parasite Plasmodium falciparum.

    Shirin Arastu-Kapur;Elizabeth L Ponder;Ursa Pecar Fonović;Sharon Yeoh

  • Inhibition of the chymotrypsin-like activity of the pituitary multicatalytic proteinase complex.

    Alexander Vinitsky;Charlene Michaud;James C. Powers;Marian Orlowski

  • Specificity of porcine pancreatic elastase, human leukocyte elastase and cathepsin G. Inhibition with peptide chloromethyl ketones.

    James C. Powers;B.Frank Gupton;A.Dale Harley;Norikazu Nishino

  • Calpain inhibitor AK295 protects neurons from focal brain ischemia. Effects of postocclusion intra-arterial administration.

    R T Bartus;N J Hayward;P J Elliott;S D Sawyer

  • Irreversible inhibition of serine proteases by peptide derivatives of (alpha-aminoalkyl)phosphonate diphenyl esters.

    Jozef Oleksyszyn;James C. Powers

  • X-ray structures of human neutrophil collagenase complexed with peptide hydroxamate and peptide thiol inhibitors. Implications for substrate binding and rational drug design.

    Frank Grams;Peter Reinemer;James C. Powers;Thomas Kleine

  • Novel Peptidyl α-Keto Amide Inhibitors of Calpains and Other Cysteine Proteases

    Zhaozhao Li;Anne-Cécile Ortega-Vilain;Girish S. Patil;Der-Lun Chu

  • Granzymes (lymphocyte serine proteases): characterization with natural and synthetic substrates and inhibitors.

    Chih-Min Kam;Dorothy Hudig;James C. Powers

  • Mammalian chymotrypsin-like enzymes: comparative reactivities of rat mast cell proteases, human and dog skin chymases, and human cathepsin G with peptide 4-nitroanilide substrates and with peptide chloromethyl ketone and sulfonyl fluoride inhibitors

    J C Powers;T Tanaka;J W Harper;Y Minematsu

  • Substrate binding site in bovine chymotrypsin A-gamma. A crystallographic study using peptide chloromethyl ketones as site-specific inhibitors.

    Segal Dm;Powers Jc;Cohen Gh;Davies Dr

  • An x-ray crystallographic study of the binding of peptide chloromethyl ketone inhibitors to subtilisin BPN'.

    John D. Robertus;Richard A. Alden;Jens J. Birktoft;Joseph Kraut

  • Design of potent reversible inhibitors for thermolysin. Peptides containing zinc coordinating ligands and their use in affinity chromatography

    Norikazu Nishino;James C. Powers

  • Crystal Structures of the Main Peptidase from the SARS Coronavirus Inhibited by a Substrate-like Aza-peptide Epoxide

    Ting-Wai Lee;Maia M. Cherney;Carly Huitema;Jie Liu

  • Inhibition of thermolysin and carboxypeptidase A by phosphoramidates.

    Chih-Min Kam;Norikazu Nishino;James C. Powers

  • Calpain as a novel target for treating acute neurodegenerative disorders

    Raymond T. Bartus;Peter J. Elliott;Neil J. Hayward;Reginald L. Dean

  • Calpain inhibition protects against Taxol-induced sensory neuropathy

    Min Sheng Wang;Albert A. Davis;Deborah G. Culver;Qinbo Wang

Frequent Co-Authors

Matthew Bogyo
Matthew Bogyo Stanford University
Guy S. Salvesen
Guy S. Salvesen Sanford Burnham Prebys Medical Discovery Institute
J. Wade Harper
J. Wade Harper Harvard Medical School
James Travis
James Travis University of Georgia
Mark J. Smyth
Mark J. Smyth QIMR Berghofer Medical Research Institute
Conor R. Caffrey
Conor R. Caffrey University of Montana
Michael N. G. James
Michael N. G. James University of Alberta
James H. McKerrow
James H. McKerrow University of California, San Diego
Kotoku Kurachi
Kotoku Kurachi University of Washington
Marcin Drag
Marcin Drag Wrocław University of Science and Technology

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