World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
77
Citations
20181
World Ranking
4808
National Ranking
2319

Overview

Helen L. Yin is affiliated with The University of Texas Southwestern Medical Center in the United States. Their research contributions span medicine, with a particular focus on fields such as gender studies, general health professions, public health, environmental and occupational health, radiology, nuclear medicine and imaging, and electrical and electronic engineering.

Their work encompasses key topics including diversity and career issues in medicine, healthcare professionals' stress and burnout, the impacts of COVID-19 on healthcare, autophagy in disease and therapy, calcium signaling and nucleotide metabolism, cellular transport and secretion, and healthcare systems and challenges.

Selected recent publications reflect a diverse research portfolio across multiple disciplines and include:

  • Academic Medicine Faculty Perceptions of Work-Life Balance Before and Since the COVID-19 Pandemic (2021, JAMA Network Open)
  • PI4P-Dependent Targeting of ATG14 to Mature Autophagosomes (2022, Biochemistry)
  • Trends in physician Medicare payments by gender and specialty (2023, The American Journal of the Medical Sciences)
  • Increasing Diversity in Academic Medicine Via a Strategic Intermural Housestaff Leadership Development Program (2024, Academic Medicine)
  • A COMPARISON OF THE EFFICACY OF DIAGNOSTIC IMAGING MODALITIES IN DETECTING COVID-19 (2020, Cambridge Medicine Journal)

Frequent collaborators in their work include Susan A. Matulevicius, Kimberly A. Kho, Joan Reisch, Hui-Qiao Sun, and Yan Chen. The research has been published in a range of venues, reflecting interdisciplinary engagement and scholarship, including:

  • JAMA Network Open
  • Biochemistry
  • The American Journal of the Medical Sciences
  • Academic Medicine
  • Cambridge Medicine Journal

Helen L. Yin's research touches significantly on the theme of diversity in academic medicine and healthcare professional wellbeing, with attention to shifts in workplace dynamics as highlighted during the COVID-19 pandemic.

Works addressing cellular and molecular mechanisms, such as autophagy and calcium signaling, demonstrate a blend of basic science alongside clinical and health system research. This points to a multifaceted approach combining clinical medicine, biomedical research, and health professions education.

Best Publications

  • Control of cytoplasmic actin gel–sol transformation by gelsolin, a calcium-dependent regulatory protein

    Helen L. Yin;Thomas P. Stossel

  • Gelsolin, a Multifunctional Actin Regulatory Protein

    Hui Qiao Sun;Masaya Yamamoto;Marisan Mejillano;Helen L. Yin

  • Phosphoinositide regulation of the actin cytoskeleton.

    Helen L. Yin;Paul A. Janmey

  • Plasma and cytoplasmic gelsolins are encoded by a single gene and contain a duplicated actin-binding domain.

    David J. Kwiatkowski;Thomas P. Stossel;Stuart H. Orkin;John E. Mole

  • Nonmuscle Actin-Binding Proteins

    Stossel Tp;Chaponnier C;Ezzell Rm;Hartwig Jh

  • Phosphatidylinositol 4,5-bisphosphate induces actin-based movement of raft-enriched vesicles through WASP-Arp2/3

    A.L. Rozelle;L.M. Machesky;M. Yamamoto;M.H.E. Driessens

  • Phosphatidylinositol 4 Phosphate Regulates Targeting of Clathrin Adaptor AP-1 Complexes to the Golgi

    Ying Jie Wang;Jing Wang;Hui Qiao Sun;Manuel Martinez

  • Phosphatidylinositol 4,5-bisphosphate and Arf6-regulated membrane traffic

    Fraser D. Brown;Andrew L. Rozelle;Helen L. Yin;Tamás Balla

  • Gelsolin superfamily proteins: key regulators of cellular functions

    P. Silacci;L. Mazzolai;C. Gauci;N. Stergiopulos

  • Actin filament disassembly is a sufficient final trigger for exocytosis in nonexcitable cells.

    Shmuel Muallem;Katarzyna Kwiatkowska;Xin Xu;Helen L. Yin

  • The Actin Cytoskeleton Is Required for Receptor-mediated Endocytosis in Mammalian Cells

    Christophe Lamaze;Christophe Lamaze;L. Miya Fujimoto;Helen L. Yin;Sandra L. Schmid

  • Polyphosphoinositide Micelles and Polyphosphoinositide-Containing Vesicles Dissociate Endogenous Gelsolin-Actin Complexes and Promote Actin Assembly From the Fast-Growing End of Actin Filaments Blocked by Gelsolin

    Paul A. Janmey;Kazuko Iida;Helen L. Yin;Thomas P. Stossel

  • Ca2+ control of actin gelation. Interaction of gelsolin with actin filaments and regulation of actin gelation.

    Helen L Yin;K. S. Zaner;T. P. Stossel

  • Ca2+ control of actin filament length. Effects of macrophage gelsolin on actin polymerization.

    Helen L Yin;J. H. Hartwig;K. Maruyama;T. P. Stossel

  • Actin monomer binding proteins

    Hui Qiao Sun;Katarzyna Kwiatkowska;Helen L. Yin

  • Identification of gelsolin, a Ca2+-dependent regulatory protein of actin gel-sol transformation, and its intracellular distribution in a variety of cells and tissues.

    H L Yin;J H Albrecht;A Fattoum

  • Structure and biosynthesis of cytoplasmic and secreted variants of gelsolin.

    H L Yin;D J Kwiatkowski;J E Mole;F S Cole

  • Identification of a polyphosphoinositide-binding sequence in an actin monomer-binding domain of gelsolin.

    Fu-Xin Yu;Hui-Qiao Sun;P. A. Janmey;H. L. Yin

  • Purification and structural properties of gelsolin, a Ca2+-activated regulatory protein of macrophages.

    H L Yin;T P Stossel

  • Interactions of gelsolin and gelsolin-actin complexes with actin. Effects of calcium on actin nucleation, filament severing, and end blocking.

    Paul A. Janmey;Christine Chaponnier;Stuart E. Lind;Ken S. Zaner

Frequent Co-Authors

Thomas P. Stossel
Thomas P. Stossel Brigham and Women's Hospital
Paul A. Janmey
Paul A. Janmey University of Pennsylvania
Joseph P. Albanesi
Joseph P. Albanesi The University of Texas Southwestern Medical Center
John H. Hartwig
John H. Hartwig Brigham and Women's Hospital
David J. Kwiatkowski
David J. Kwiatkowski Brigham and Women's Hospital
Jing Wang
Jing Wang The University of Texas MD Anderson Cancer Center
Robert Robinson
Robert Robinson Okayama University
Pascale Cossart
Pascale Cossart Institut Pasteur
Javier Pizarro-Cerdá
Javier Pizarro-Cerdá Institut Pasteur
Thomas C. Südhof
Thomas C. Südhof Stanford University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Helen L. Yin

Trending Scientists

Recently Published Articles