World's Best Scientists 2026 revealed!
Toshihiko Osawa

Toshihiko Osawa

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Biology and Biochemistry
Japan
2026
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Chemistry
Japan
2026

D-Index & Metrics

Chemistry

D-Index
103
Citations
35199
World Ranking
1123
National Ranking
51

Biology and Biochemistry

D-Index
104
Citations
34934
World Ranking
1271
National Ranking
71

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Japan Leader Award
  • 2026 - Research.com Chemistry in Japan Leader Award
  • 2025 - Research.com Biology and Biochemistry in Japan Leader Award
  • 2025 - Research.com Chemistry in Japan Leader Award
  • 2023 - Research.com Biology and Biochemistry in Japan Leader Award
  • 2022 - Research.com Chemistry in Japan Leader Award

Overview

Toshihiko Osawa is affiliated with Nagoya University in Japan and has contributed extensively to research in biochemistry, genetics, molecular biology, and medicine. Their publication record encompasses a broad range of topics within these fields, particularly focusing on molecular biology, pathology and forensic medicine, biochemistry, nutrition and dietetics, and molecular medicine.

Their research involves several thematic areas, including:

  • Phytochemicals and antioxidant activities
  • Phytoestrogen effects and research
  • Curcumin's biomedical applications
  • Natural product bioactivities and synthesis
  • Fungal biology and applications
  • Tea polyphenols and effects
  • Melanin and skin pigmentation

Among their recent publications are:

  • Red Clover (Trifolium pratense L.) Sprout Prevents Metabolic Syndrome, 2020, Journal of Nutritional Science and Vitaminology
  • Effects of isoflavone-rich red clover extract on blood glucose level: A randomized, double-blind, placebo-controlled trial, 2021, Journal of Food Science
  • Correlation between human health and reactive oxygen species produced in blood: a long-term chemiluminescence and fluorescence analysis, 2021, Scientific Reports
  • Equol Inhibits Mushroom Tyrosinase in Vitro through Tight Binding, 2020, Biological and Pharmaceutical Bulletin
  • Oxidized Perilla and Linseed Oils Induce Neuronal Apoptosis by Caspase-Dependent and -Independent Pathways, 2020, Foods

Osawa collaborates frequently with several coauthors, including:

  • Shin-ichiro Yokoyama (6 joint publications)
  • Toshio Niwa (6 joint publications)
  • Mika Mochizuki (5 joint publications)
  • Akiko Hirai (3 joint publications)
  • Yuki Ueno (3 joint publications)

Their work is often published in specialized venues such as:

  • Biological and Pharmaceutical Bulletin (4 publications)
  • Journal of Nutritional Science and Vitaminology (3 publications)
  • Food Science and Technology Research (2 publications)
  • Journal of Food Science (1 publication)
  • Scientific Reports (1 publication)

Best Publications

  • Dietary cyanidin 3-O-beta-D-glucoside-rich purple corn color prevents obesity and ameliorates hyperglycemia in mice.

    Takanori Tsuda;Fumihiko Horio;Koji Uchida;Hiromitsu Aoki

  • Protein-bound acrolein: Potential markers for oxidative stress

    Koji Uchida;Masamichi Kanematsu;Kensuke Sakai;Tsukasa Matsuda

  • Quantitative immunohistochemical determination of 8-hydroxy-2'-deoxyguanosine by a monoclonal antibody N45.1: its application to ferric nitrilotriacetate-induced renal carcinogenesis model

    S. Toyokuni;T. Tanaka;Y. Hattori;Y. Nishiyama

  • Acrolein Is a Product of Lipid Peroxidation Reaction: FORMATION OF FREE ACROLEIN AND ITS CONJUGATE WITH LYSINE RESIDUES IN OXIDIZED LOW DENSITY LIPOPROTEINS *

    Koji Uchida;Masamichi Kanematsu;Yasujiro Morimitsu;Toshihiko Osawa

  • Activation of Stress Signaling Pathways by the End Product of Lipid Peroxidation: 4-HYDROXY-2-NONENAL IS A POTENTIAL INDUCER OF INTRACELLULAR PEROXIDE PRODUCTION *

    Koji Uchida;Mihoko Shiraishi;Yuko Naito;Yasuyoshi Torii

  • Hydroxyl Radical-scavenging Effects of Spices and Scavengers from Brown Mustard (Brassica nigra)

    Shin-Kyo Chung;Toshihiko Osawa;Shunro Kawakishi

  • 15-Deoxy-Δ12,14-prostaglandin J2: A PROSTAGLANDIN D2 METABOLITE GENERATED DURING INFLAMMATORY PROCESSES

    Takahiro Shibata;Mitsuhiro Kondo;Toshihiko Osawa;Noriyuki Shibata

  • Methylglyoxal Modification of Protein: CHEMICAL AND IMMUNOCHEMICAL CHARACTERIZATION OF METHYLGLYOXAL-ARGININE ADDUCTS *

    Tomoko Oya;Nobutaka Hattori;Yoshikuni Mizuno;Satoshi Miyata

  • Involvement of the β-diketone moiety in the antioxidative Mechanism of Tetrahydrocurcumin

    Yosunori Sugiyama;Shunro Kawakishi;Toshihiko Osawa

  • Inhibition of lipid peroxidation and the active oxygen radical scavenging effect of anthocyanin pigments isolated from Phaseolus vulgaris L.

    Takanori Tsuda;Kaoru Shiga;Katsumi Ohshima;Shunro Kawakishi

  • Absorption and metabolism of cyanidin 3-O-β-D-glucoside in rats

    Takanori Tsuda;Fumihiko Horio;Toshihiko Osawa

  • A Novel type of antioxidant isolated from leaf wax of eucalyptus leaves

    Toshihiko Osawa;Mitsuo Namiki

  • Antioxidative Activity of Tetrahydrocurcuminoids

    Toshihiko Osawa;Yasunori Sugiyama;Masanori Inayoshi;Shunro Kawakishi

  • The contribution of plant food antioxidants to human health

    Narasimhan Ramarathnam;Toshihiko Osawa;Hirotomo Ochi;Shunro Kawakishi

  • Biomarker evidence of DNA oxidation in lung cancer patients: association of urinary 8-hydroxy-2′-deoxyguanosine excretion with radiotherapy, chemotherapy, and response to treatment

    Marina Erhola;Shinya Toyokuni;Kunihiko Okada;Tomoyuki Tanaka

  • 4-Hydroxy-2-nonenal-mediated impairment of intracellular proteolysis during oxidative stress. Identification of proteasomes as target molecules.

    Kunihiko Okada;Chantima Wangpoengtrakul;Toshihiko Osawa;Shinya Toyokuni

  • Chemopreventive effects of carotenoids and curcumins on mouse colon carcinogenesis after 1,2-dimethylhydrazine initiation.

    Jin Man Kim;Shunichi Araki;Dae Joong Kim;Cheol Beom Park

  • Antioxidative activity of the anthocyanin pigments cyanidin 3-O-beta-D-glucoside and cyanidin

    Takanori Tsuda;Mie Watanabe;Katsumi Ohshima;Seiji Norinobu

  • Contribution of lignan analogues to antioxidative activity of refined unroasted sesame seed oil

    Y. Fukuda;M. Nagata;T. Osawa;M. Namiki

  • Curcumin and Especially Tetrahydrocurcumin Ameliorate Oxidative Stress-Induced Renal Injury in Mice

    Kunihiko Okada;Chantima Wangpoengtrakul;Tomoyuki Tanaka;Shinya Toyokuni

  • Protective Role of Antioxidative Food Factors in Oxidative Stress Caused by Hyperglycemia

    Toshihiko Osawa;Yoji Kato

Frequent Co-Authors

Shunro Kawakishi
Shunro Kawakishi Sugiyama Jogakuen University
Koji Uchida
Koji Uchida University of Tokyo
Yoji Kato
Yoji Kato University of Hyogo
Yoshimasa Nakamura
Yoshimasa Nakamura Okayama University
Shinya Toyokuni
Shinya Toyokuni Nagoya University
Hiroshi Hiai
Hiroshi Hiai Kyoto University
Hajime Ohigashi
Hajime Ohigashi Kyoto University
Toshikazu Yoshikawa
Toshikazu Yoshikawa Kyoto Prefectural University of Medicine
Junji Terao
Junji Terao University of Tokushima
Akira Murakami
Akira Murakami Kyoto University

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