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59
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3254
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Overview

Cynthia T. McMurray is affiliated with Lawrence Berkeley National Laboratory in the United States. Their research focuses primarily on biochemistry, genetics, and molecular biology, with a strong emphasis on molecular biology and biophysics. They have also contributed to studies related to infectious diseases, analytical chemistry, and cancer research.

Their work extensively covers a variety of scientific topics, including:

  • Spectroscopy Techniques in Biomedical and Chemical Research
  • DNA Repair Mechanisms
  • CRISPR and Genetic Engineering
  • Mitochondrial Function and Pathology
  • SARS-CoV-2 and COVID-19 Research
  • Spectroscopy and Chemometric Analyses
  • Metabolomics and Mass Spectrometry Studies

Some of the recent publications by Cynthia T. McMurray include the following papers:

  • "An infrared spectral biomarker accurately predicts neurodegenerative disease class in the absence of overt symptoms," 2021, Scientific Reports
  • "Flap Endonuclease 1 Endonucleolytically Processes RNA to Resolve R-Loops through DNA Base Excision Repair," 2022, Genes
  • "Base excision repair and double strand break repair cooperate to modulate the formation of unrepaired double strand breaks in mouse brain," 2024, Nature Communications
  • "XJB-5-131 Is a Mild Uncoupler of Oxidative Phosphorylation," 2022, Journal of Huntington's Disease
  • "Double strand breaks drive toxicity in Huntington's disease mice with or without somatic expansion," 2025, bioRxiv (Cold Spring Harbor Laboratory)

They frequently publish in several scientific venues, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Scientific Reports
  • Genes
  • Nature Communications
  • Journal of Huntington's Disease

Collaboration plays an important role in their research. Frequent co-authors include:

  • Aris Polyzos
  • James Brown
  • Brandon Saint-John
  • Alejandro Wolf-Yadlin
  • Daniel E. Jacobsen

Best Publications

  • Trinucleotide repeats that expand in human disease form hairpin structures in vitro

    A. Marquis Gacy;Geoffrey Goellner;Nenad Juranić;Slobodan Macura

  • The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair

    Karl Peter Hopfner;Lisa Craig;Gabriel Moncalian;Robert A. Zinkel

  • Mutant huntingtin impairs axonal trafficking in mammalian neurons in vivo and in vitro.

    Eugenia Trushina;Roy B. Dyer;John D. Badger;Daren Ure

  • Mechanisms of trinucleotide repeat instability during human development.

    Cynthia T. McMurray

  • Oxidative stress and mitochondrial dysfunction in neurodegenerative diseases

    E. Trushina;C.T. McMurray

  • OGG1 initiates age-dependent CAG trinucleotide expansion in somatic cells

    Irina V. Kovtun;Yuan Liu;Magnar Bjoras;Arne Klungland

  • Trinucleotide expansion in haploid germ cells by gap repair

    Irina V. Kovtun;Cynthia T. McMurray

  • (CAG)(n)-hairpin DNA binds to Msh2-Msh3 and changes properties of mismatch recognition.

    Barbara A L Owen;Zungyoon Yang;Maoyi Lai;Maciez Gajek

  • DNA secondary structure: A common and causative factor for expansion in human disease

    Cynthia T. McMurray

  • Salt-induced release of DNA from nucleosome core particles.

    Thomas D. Yager;Cynthia T. McMurray;K. E. Van Holde

  • Cancer, cadmium and genome integrity

    Cynthia T McMurray;John A Tainer

  • GAA Instability in Friedreich's Ataxia Shares a Common, DNA-Directed and Intraallelic Mechanism with Other Trinucleotide Diseases

    A.Marquis Gacy;Geoffrey M Goellner;Craig Spiro;Xian Chen

  • Inhibition of FEN-1 processing by DNA secondary structure at trinucleotide repeats.

    Craig Spiro;Richard Pelletier;Michael L Rolfsmeier;Michael J Dixon

  • Function of Hexameric RNA in Packaging of Bacteriophage φ29 DNA In Vitro

    Feng Zhang;Sébastien Lemieux;Xiling Wu;Daniel St.-Arnaud

  • Mechanisms of DNA expansion.

    Cynthia T. McMurray

  • Features of trinucleotide repeat instability in vivo

    Irina V Kovtun;Cynthia T McMurray

  • Increased instability of intermediate alleles in families with sporadic Huntington disease compared to similar sized intermediate alleles in the general population

    Y P Goldberg;C T McMurray;J Zeisler;E Almqvist

  • Recombination-induced CAG trinucleotide repeat expansions in yeast involve the MRE11-RAD50-XRS2 complex.

    Guy-Franck Richard;Guy-Franck Richard;Geoffrey M. Goellner;Cynthia T. McMurray;James E. Haber

  • Comprehensive macromolecular conformations mapped by quantitative SAXS analyses.

    Greg L Hura;Helen Budworth;Kevin N Dyer;Robert P Rambo

  • Erratum: Mechanisms of trinucleotide repeat instability during human development

    Cynthia T. McMurray

Frequent Co-Authors

Magnar Bjørås
Magnar Bjørås Norwegian University of Science and Technology
John A. Tainer
John A. Tainer The University of Texas MD Anderson Cancer Center
Peter Wipf
Peter Wipf University of Pittsburgh
Michael R. Hayden
Michael R. Hayden University of British Columbia
K. E. Van Holde
K. E. Van Holde Oregon State University
Dwight L. Anderson
Dwight L. Anderson University of Minnesota
Winfried Edelmann
Winfried Edelmann Albert Einstein College of Medicine
Raju Kucherlapati
Raju Kucherlapati Harvard University

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