His primary areas of investigation include Immunology, Inflammation, Bronchoalveolar lavage, Ovalbumin and Cytokine. His Immunology research includes themes of Inhalation and Respiratory system. The concepts of his Respiratory system study are interwoven with issues in In vivo and Lung, Pulmonary toxicity.
His Inflammation research includes themes of Oxidative stress, Lipopolysaccharide, Lung injury and Apoptosis. His Proinflammatory cytokine study integrates concerns from other disciplines, such as Systemic inflammation, Pharmacology and Monocyte. His Pharmacology research includes elements of Nasal Lavage Fluid, Biochemistry and Chemokine.
His primary scientific interests are in Immunology, Inflammation, Internal medicine, Lung and Endocrinology. His Immunology study frequently draws connections to adjacent fields such as Bronchoalveolar lavage. His Inflammation research focuses on Interleukin and how it relates to Peripheral blood mononuclear cell and Molecular biology.
He works mostly in the field of Lung, limiting it down to topics relating to Pharmacology and, in certain cases, Rosmarinic acid, as a part of the same area of interest. His research investigates the connection between Lipopolysaccharide and topics such as Lung injury that intersect with problems in Oxidative stress. The various areas that he examines in his Ovalbumin study include Immunoglobulin E and Allergen, Allergy, Allergic inflammation.
Hirohisa Takano spends much of his time researching Immunology, Respiratory system, Immune system, Ovalbumin and Proinflammatory cytokine. Hirohisa Takano regularly links together related areas like Bronchoalveolar lavage in his Immunology studies. He has researched Bronchoalveolar lavage in several fields, including Chemokine, Eosinophil, Inflammation, Eotaxin and Eosinophilia.
His Inflammation research incorporates themes from Tumor necrosis factor alpha, Lung and Pharmacology. His study focuses on the intersection of Immune system and fields such as Interleukin with connections in the field of Splenocyte, Peripheral blood mononuclear cell, Interferon gamma and Molecular biology. Hirohisa Takano combines subjects such as Receptor, Internal medicine and Endocrinology with his study of Ovalbumin.
The scientist’s investigation covers issues in Immunology, Respiratory system, Bronchoalveolar lavage, Proinflammatory cytokine and Immune system. His research combines Tight junction and Immunology. His Bronchoalveolar lavage research is multidisciplinary, incorporating elements of Inflammation, Lipopolysaccharide and Ovalbumin.
His study looks at the relationship between Lipopolysaccharide and topics such as Pharmacology, which overlap with Oxidative stress. His Proinflammatory cytokine study incorporates themes from Tumor necrosis factor alpha, Epidermal growth factor, Protein kinase A and Monocyte. His Immune system research is multidisciplinary, relying on both Interleukin, Epithelium and Microbiology.
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Diesel Exhaust Particles Enhance Antigen-induced Airway Inflammation and Local Cytokine Expression in Mice
Hirohisa Takano;Toshikazu Yoshikawa;Takamichi Ichinose;Yuichi Miyabara.
American Journal of Respiratory and Critical Care Medicine (1997)
Extract of Perilla frutescens Enriched for Rosmarinic Acid, a Polyphenolic Phytochemical, Inhibits Seasonal Allergic Rhinoconjunctivitis in Humans
Hirohisa Takano;Hirohisa Takano;Naomi Osakabe;Chiaki Sanbongi;Rie Yanagisawa.
Experimental Biology and Medicine (2004)
Anti‐inflammatory and anti‐allergic effect of rosmarinic acid (RA); inhibition of seasonal allergic rhinoconjunctivitis (SAR) and its mechanism
Naomi Osakabe;Hirohisa Takano;Hirohisa Takano;Chiaki Sanbongi;Akiko Yasuda.
Biofactors (2004)
Rosmarinic acid in perilla extract inhibits allergic inflammation induced by mite allergen, in a mouse model
C. Sanbongi;H. Takano;H. Takano;N. Osakabe;N. Sasa.
Clinical & Experimental Allergy (2004)
Role of Interleukin-6 in Bleomycin-Induced Lung Inflammatory Changes in Mice
Fumitake Saito;Sadatomo Tasaka;Ken Ichiro Inoue;Keisuke Miyamoto.
American Journal of Respiratory Cell and Molecular Biology (2008)
Increased susceptibility of MER5 (peroxiredoxin III) knockout mice to LPS-induced oxidative stress
Lianqin Li;Wataru Shoji;Hirohisa Takano;Noriko Nishimura.
Biochemical and Biophysical Research Communications (2007)
Diesel Exhaust Enhances Allergic Airway Inflammation and Hyperresponsiveness in Mice
Yuichi Miyabara;Hirohisa Takano;Takamichi Ichinose;Heung-Bin Lim.
American Journal of Respiratory and Critical Care Medicine (1998)
Dietary supplementation with cacao liquor proanthocyanidins prevents elevation of blood glucose levels in diabetic obese mice
Makoto Tomaru;Makoto Tomaru;Hirohisa Takano;Hirohisa Takano;Naomi Osakabe;Akiko Yasuda.
Nutrition (2007)
Prenatal exposure to bisphenol A up-regulates immune responses, including T helper 1 and T helper 2 responses, in mice.
Shin Yoshino;Kouya Yamaki;Xiaojuan Li;Tao Sai.
Immunology (2004)
Effect of nanoparticles on the male reproductive system of mice.
S. Yoshida;K. Hiyoshi;T. Ichinose;H. Takano.
International Journal of Andrology (2009)
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