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Biology and Biochemistry

D-Index
65
Citations
13316
World Ranking
9268
National Ranking
625

Overview

Tomohisa Takagi is affiliated with Kyoto Prefectural University of Medicine in Japan. Their research intersects medicine and biochemistry, genetics, and molecular biology, with a specific focus on several subfields including surgery, molecular biology, epidemiology, genetics, and pulmonary and respiratory medicine.

The scientist's work concentrates on health-related aspects of gut microbiota, inflammatory bowel disease, and gastrointestinal cancers such as gastric and esophageal cancer. Other main topics include Helicobacter pylori-related gastroenterology, diet and metabolism studies, and microscopic colitis.

Takagi has contributed to numerous publications, frequently collaborating with other researchers including Yuji Naito, Kazuhiko Uchiyama, Yoshito Itoh, Takeshi Ishikawa, and Hideyuki Konishi. The most frequent venues for publication feature journals focused on clinical biochemistry, gastroenterology, and inflammatory bowel disease.

  • Journal of Clinical Biochemistry and Nutrition (13 publications)
  • Gastroenterology (8 publications)
  • Journal of Gastroenterology (7 publications)
  • Journal of Crohn's and Colitis (7 publications)
  • Journal of Gastroenterology and Hepatology (6 publications)

Examples of recent papers with Takagi as an author or coauthor include:

  • "Changes in the Gut Microbiota are Associated with Hypertension, Hyperlipidemia, and Type 2 Diabetes Mellitus in Japanese Subjects", 2020, Nutrients
  • "Full-length 16S rRNA gene amplicon analysis of human gut microbiota using MinION™ nanopore sequencing confers species-level resolution", 2021, BMC Microbiology
  • "Intake of sucrose affects gut dysbiosis in patients with type 2 diabetes", 2020, Journal of Diabetes Investigation
  • "Epigallocatechin-3-gallate (EGCG) attenuates non-alcoholic fatty liver disease via modulating the interaction between gut microbiota and bile acids", 2020, Journal of Clinical Biochemistry and Nutrition
  • "Efficacy and safety of 48 weeks of guselkumab for patients with Crohn's disease: maintenance results from the phase 2, randomised, double-blind GALAXI-1 trial", 2023, The Lancet. Gastroenterology & Hepatology

Best Publications

  • Silver nanoparticles as a safe preservative for use in cosmetics

    Satoshi Kokura;Osamu Handa;Tomohisa Takagi;Takeshi Ishikawa

  • A novel myokine, secreted protein acidic and rich in cysteine (SPARC), suppresses colon tumorigenesis via regular exercise

    Wataru Aoi;Yuji Naito;Tomohisa Takagi;Yuko Tanimura

  • Heme oxygenase-1 and anti-inflammatory M2 macrophages.

    Yuji Naito;Tomohisa Takagi;Yasuki Higashimura

  • Differences in gut microbiota associated with age, sex, and stool consistency in healthy Japanese subjects.

    Tomohisa Takagi;Yuji Naito;Ryo Inoue;Saori Kashiwagi

  • A next-generation beneficial microbe: Akkermansia muciniphila.

    Yuji Naito;Kazuhiko Uchiyama;Tomohisa Takagi

  • Increased expression of microRNA in the inflamed colonic mucosa of patients with active ulcerative colitis.

    Tomohisa Takagi;Yuji Naito;Katsura Mizushima;Ikuhiro Hirata

  • Full-length 16S rRNA gene amplicon analysis of human gut microbiota using MinION™ nanopore sequencing confers species-level resolution.

    Yoshiyuki Matsuo;Shinnosuke Komiya;Yoshiaki Yasumizu;Yuki Yasuoka

  • Enhanced intestinal inflammation induced by dextran sulfate sodium in tumor necrosis factor-alpha deficient mice

    Yuji Naito;Tomohisa Takagi;Osamu Handa;Takeshi Ishikawa

  • Methylparaben potentiates UV-induced damage of skin keratinocytes.

    Osamu Handa;Satoshi Kokura;Satoko Adachi;Tomohisa Takagi

  • Astaxanthin protects mesangial cells from hyperglycemia-induced oxidative signaling†

    Emiko Manabe;Osamu Handa;Yuji Naito;Katsura Mizushima

  • The JAK/STAT pathway is involved in the upregulation of PD-L1 expression in pancreatic cancer cell lines.

    Toshifumi Doi;Takeshi Ishikawa;Tetsuya Okayama;Kaname Oka

  • Molecular fingerprints of neutrophil-dependent oxidative stress in inflammatory bowel disease.

    Yuji Naito;Tomohisa Takagi;Toshikazu Yoshikawa

  • Molecular mechanisms involved in anti-inflammatory effects of proton pump inhibitors

    O Handa;N Yoshida;N Fujita;Y Tanaka

  • Ability of a novel blue laser imaging system for the diagnosis of colorectal polyps

    Naohisa Yoshida;Nobuaki Yagi;Yutaka Inada;Munehiro Kugai

  • Green tea polyphenol (epigallocatechin-3-gallate) improves gut dysbiosis and serum bile acids dysregulation in high-fat diet-fed mice.

    Chihiro Ushiroda;Yuji Naito;Tomohisa Takagi;Kazuhiko Uchiyama

  • Neutrophil-Dependent Oxidative Stress in Ulcerative Colitis

    Yuji Naito;Tomohisa Takagi;Toshikazu Yoshikawa

  • Reduced intestinal inflammation induced by dextran sodium sulfate in interleukin-6-deficient mice.

    Yuji Naito;Tomohisa Takagi;Kazuhiko Uchiyama;Masaaki Kuroda

  • Linked color imaging improves endoscopic diagnosis of active Helicobacter pylori infection

    Osamu Dohi;Nobuaki Yagi;Yuriko Onozawa;Reiko Kimura-Tsuchiya

  • The influence of long-term use of proton pump inhibitors on the gut microbiota: an age-sex-matched case-control study.

    Tomohisa Takagi;Yuji Naito;Ryo Inoue;Saori Kashiwagi

  • Galectin-9 exhibits anti-myeloma activity through JNK and p38 MAP kinase pathways

    T Kobayashi;J Kuroda;E Ashihara;S Oomizu

Frequent Co-Authors

Yuji Naito
Yuji Naito Kyoto Prefectural University of Medicine
Toshikazu Yoshikawa
Toshikazu Yoshikawa Kyoto Prefectural University of Medicine
Kazuhiko Igarashi
Kazuhiko Igarashi Tohoku University
Takashi Suzuki
Takashi Suzuki Tohoku University
Yoji Kato
Yoji Kato University of Hyogo
Hirohisa Takano
Hirohisa Takano Kyoto University
Motoharu Kondo
Motoharu Kondo Kyoto Prefectural University of Medicine
Kiichi Hirota
Kiichi Hirota Kansai Medical University
Akio Inui
Akio Inui Kagoshima University
Takeshi Azuma
Takeshi Azuma Kobe University

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