Yukio Nagasaki

Overview

Best Publications

• Block copolymer micelles for drug delivery: design, characterization and biological significance

  Kazunori Kataoka;Atsushi Harada;Yukio Nagasaki

  4615
  Citations

• PEGylated Nanoparticles for Biological and Pharmaceutical Applications

  Hidenori Otsuka;Yukio Nagasaki;Kazunori Kataoka

  2080
  Citations

• Lactosylated poly(ethylene glycol)-sIRNA conjugate through acid-labile β-thiopropionate linkage to construct pH-sensitive polyion complex micelles achieving enhanced gene silencing in hepatoma cells

  Motoi Oishi;Yukio Nagasaki;Keiji Itaka;Nobuhiro Nishiyama

  714
  Citations

• Quantitative and Reversible Lectin-Induced Association of Gold Nanoparticles Modified with α-Lactosyl-ω-mercapto-poly(ethylene glycol)

  Hidenori Otsuka;Yoshitsugu Akiyama;Yukio Nagasaki;Kazunori Kataoka

  626
  Citations

• Long-circulating poly(ethylene glycol)-poly(D,L-lactide) block copolymer micelles with modulated surface charge.

  Yuji Yamamoto;Yukio Nagasaki;Yukio Kato;Yuichi Sugiyama

  551
  Citations

• PEGylated nanoparticles for biological and pharmaceutical applications.

  Unknown

  547
  Citations

• Development of a novel systemic gene delivery system for cancer therapy with a tumor-specific cleavable PEG-lipid.

  H Hatakeyama;H Akita;K Kogure;M Oishi

  488
  Citations

• Core-Polymerized Reactive Micelles from Heterotelechelic Amphiphilic Block Copolymers

  Michihiro Iijima;Yukio Nagasaki;Takashi Okada;Masao Kato

  329
  Citations

• Self-assembly of poly(ethylene glycol)-based block copolymers for biomedical applications

  Hidenori Otsuka;Yukio Nagasaki;Kazunori Kataoka

  314
  Citations

• Preparation and characterization of polymer micelles from poly(ethylene glycol)-poly(D,L-lactide) block copolymers as potential drug carrier.

  Kenji Yasugi;Yukio Nagasaki;Masao Kato;Kazunori Kataoka

  311
  Citations

• The Reactive Polymeric Micelle Based on An Aldehyde-Ended Poly(ethylene glycol)/Poly(lactide) Block Copolymer

  Yukio Nagasaki;Takashi Okada;Carmen Scholz;Michihiro Iijima

  306
  Citations

• A pH-sensitive fusogenic peptide facilitates endosomal escape and greatly enhances the gene silencing of siRNA-containing nanoparticles in vitro and in vivo.

  Hiroto Hatakeyama;Erika Ito;Hidetaka Akita;Motoi Oishi

  290
  Citations

• Preparation of functionally PEGylated gold nanoparticles with narrow distribution through autoreduction of auric cation by α-Biotinyl-PEG-block-[poly(2-(N,N-dimethylamino)ethyl methacrylate)]

  Takehiko Ishii;Hidenori Otsuka;Kazunori Kataoka;Yukio Nagasaki

  286
  Citations

• A Reactive Poly(ethylene glycol) Layer To Achieve Specific Surface Plasmon Resonance Sensing with a High S/N Ratio: The Substantial Role of a Short Underbrushed PEG Layer in Minimizing Nonspecific Adsorption

  Katsumi Uchida;Hidenori Otsuka;Mitsuhiro Kaneko;Kazunori Kataoka

  267
  Citations

• Sugar-Installed Polymer Micelles: Synthesis and Micellization of Poly(ethylene glycol)−Poly(d,l-lactide) Block Copolymers Having Sugar Groups at the PEG Chain End

  Kenji Yasugi;Teruo Nakamura;Yukio Nagasaki;Masao Kato

  253
  Citations

• Systemic delivery of siRNA to tumors using a lipid nanoparticle containing a tumor-specific cleavable PEG-lipid.

  Hiroto Hatakeyama;Hidetaka Akita;Erika Ito;Yasuhiro Hayashi

  245
  Citations

• Sugar-installed block copolymer micelles: their preparation and specific interaction with lectin molecules.

  Yukio Nagasaki;Kenji Yasugi;Yuji Yamamoto;and Atsushi Harada

  245
  Citations

• Heterotelechelisk blokk-kopolymer og en fremgangsmåte for fremstilling derav og anvendelse i höymolekyl¶re miceller

  Kataoka Kazunori;Scholz Carmen;Iijima Michihiro;Kutsuna Takahiko

  232
  Citations

• Ligand Density Effect on Biorecognition by PEGylated Gold Nanoparticles: Regulated Interaction of RCA120 Lectin with Lactose Installed to the Distal End of Tethered PEG Strands on Gold Surface

  Seiji Takae;Yoshitsugu Akiyama;Hidenori Otsuka;Teisaku Nakamura

  227
  Citations

• Smart PEGylated Gold Nanoparticles for the Cytoplasmic Delivery of siRNA to Induce Enhanced Gene Silencing

  Motoi Oishi;Junpei Nakaogami;Takehiko Ishii;Yukio Nagasaki

  215
  Citations

• Endosomal release and intracellular delivery of anticancer drugs using pH-sensitive PEGylated nanogels

  Motoi Oishi;Hisato Hayashi;Michihiro Iijima;Yukio Nagasaki

  211
  Citations