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Horacio Cabral

Horacio Cabral

D-Index & Metrics

Chemistry

D-Index
61
Citations
17308
World Ranking
9120
National Ranking
644

Overview

Horacio Cabral is affiliated with the University of Tokyo in Japan, where their research spans multiple aspects of biochemistry, genetics, molecular biology, and medicine. Their work focuses heavily on molecular biology, with notable contributions in biomaterials, biomedical engineering, immunology, and oncology. These subfields intersect within their overarching interest in advanced therapeutic delivery systems and cancer-related biomedical applications.

Cabral's research topics cover a range of areas including RNA interference and gene delivery, nanoparticle-based drug delivery, and advanced biosensing and bioanalysis techniques. Their work also engages with nanoplatforms for cancer theranostics, cancer cells and metastasis, immunotherapy, immune responses, and the role of immune cells in cancer.

Frequent publication venues for Cabral include:

  • Journal of Controlled Release
  • ACS Nano
  • Preprints.org
  • Advanced Healthcare Materials
  • Biomaterials

Among Cabral's recent papers are:

  • "Improving cancer immunotherapy using nanomedicines: progress, opportunities and challenges," 2020, Nature Reviews Clinical Oncology
  • "TGF-β inhibition combined with cytotoxic nanomedicine normalizes triple negative breast cancer microenvironment towards anti-tumor immunity," 2020, Theranostics
  • "Interplay of EMT and CSC in Cancer and the Potential Therapeutic Strategies," 2020, Frontiers in Pharmacology
  • "Controlling the biodistribution and clearance of nanomedicines," 2023, Nature Reviews Bioengineering
  • "Polymer-Based mRNA Delivery Strategies for Advanced Therapies," 2023, Advanced Healthcare Materials

Cabral frequently collaborates with several coauthors, including Kazunori Kataoka, Pengwen Chen, Sabina Quader, Taehun Hong, and Takuya Miyazaki. The breadth of these collaborations reflects a multidisciplinary approach to research in nanomedicine and drug delivery systems.

Their primary fields of study are divided as follows:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

The subfields in which Cabral has published extensively include:

  • Molecular Biology
  • Biomaterials
  • Biomedical Engineering
  • Immunology
  • Oncology

Main topics of Cabral's research work include:

  • RNA Interference and Gene Delivery
  • Nanoparticle-Based Drug Delivery
  • Advanced biosensing and bioanalysis techniques
  • Nanoplatforms for cancer theranostics
  • Cancer Cells and Metastasis
  • Immunotherapy and Immune Responses
  • Immune cells in cancer

Best Publications

  • Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size

    H. Cabral;Y. Matsumoto;K. Mizuno;Q. Chen

  • Block Copolymer Micelles in Nanomedicine Applications.

    Horacio Cabral;Kanjiro Miyata;Kensuke Osada;Kazunori Kataoka

  • Progress of drug-loaded polymeric micelles into clinical studies

    Horacio Cabral;Kazunori Kataoka

  • Novel Cisplatin-Incorporated Polymeric Micelles Can Eradicate Solid Tumors in Mice

    Nobuhiro Nishiyama;Souichiro Okazaki;Horacio Cabral;Masaki Miyamoto

  • Improving cancer immunotherapy using nanomedicines: progress, opportunities and challenges.

    John D. Martin;Horacio Cabral;Triantafyllos Stylianopoulos;Rakesh K. Jain

  • Highly cited research articles in Journal of Controlled Release: Commentaries and perspectives by authors

    Nicholas A. Peppas;Ruth Duncan;Gary E. Wnek;Allan S. Hoffman

  • A pH-activatable nanoparticle with signal-amplification capabilities for non-invasive imaging of tumour malignancy

    Peng Mi;Peng Mi;Daisuke Kokuryo;Horacio Cabral;Hailiang Wu

  • Cyclic RGD-linked polymeric micelles for targeted delivery of platinum anticancer drugs to glioblastoma through the blood-brain tumor barrier

    Yutaka Miura;Tomoya Takenaka;Kazuko Toh;Shourong Wu

  • Vascular bursts enhance permeability of tumour blood vessels and improve nanoparticle delivery.

    Yu Matsumoto;Joseph W. Nichols;Kazuko Toh;Takahiro Nomoto

  • Charge‐Conversional Polyionic Complex Micelles—Efficient Nanocarriers for Protein Delivery into Cytoplasm

    Yan Lee;Takehiko Ishii;Horacio Cabral;Hyun Jin Kim

  • Phenylboronic Acid-Installed Polymeric Micelles for Targeting Sialylated Epitopes in Solid Tumors

    Stephanie Deshayes;Horacio Cabral;Takehiko Ishii;Yutaka Miura

  • Supramolecular nanodevices: from design validation to theranostic nanomedicine.

    Horacio Cabral;Nobuhiro Nishiyama;Kazunori Kataoka

  • Ligand-Installed Nanocarriers toward Precision Therapy.

    Peng Mi;Horacio Cabral;Kazunori Kataoka

  • Improving Drug Potency and Efficacy by Nanocarrier-Mediated Subcellular Targeting

    Mami Murakami;Horacio Cabral;Yu Matsumoto;Shourong Wu

  • Preparation and biological properties of dichloro(1,2-diaminocyclohexane)platinum(II) (DACHPt)-loaded polymeric micelles

    Horacio Cabral;Nobuhiro Nishiyama;Soichiro Okazaki;Hiroyuki Koyama

  • Assessment of Tumor Metastasis by the Direct Determination of Cell‐Membrane Sialic Acid Expression

    Akira Matsumoto;Horacio Cabral;Naoko Sato;Kazunori Kataoka

  • Polyion Complex Vesicles for Photoinduced Intracellular Delivery of Amphiphilic Photosensitizer

    Huabing Chen;Ling Xiao;Yasutaka Anraku;Peng Mi

  • Optimization of (1,2 -diamino -cyclohexane )platinum (II ) -loaded polymeric micelles directed to improved tumor targeting and enhanced antitumor activity

    Horacio Cabral;Nobuhiro Nishiyama;Kazunori Kataoka

  • Bundled assembly of helical nanostructures in polymeric micelles loaded with platinum drugs enhancing therapeutic efficiency against pancreatic tumor.

    Yuki Mochida;Horacio Cabral;Yutaka Miura;Francesco Albertini

  • Systemic Targeting of Lymph Node Metastasis through the Blood Vascular System by Using Size-Controlled Nanocarriers.

    Horacio Cabral;Jun Makino;Yu Matsumoto;Peng Mi

  • Interplay of EMT and CSC in Cancer and the Potential Therapeutic Strategies.

    Shihori Tanabe;Sabina Quader;Horacio Cabral;Ryuichi Ono

  • Visible drug delivery by supramolecular nanocarriers directing to single-platformed diagnosis and therapy of pancreatic tumor model.

    Sachiko Kaida;Horacio Cabral;Michiaki Kumagai;Akihiro Kishimura

Frequent Co-Authors

Kazunori Kataoka
Kazunori Kataoka University of Tokyo
Nobuhiro Nishiyama
Nobuhiro Nishiyama Tokyo Institute of Technology
Kanjiro Miyata
Kanjiro Miyata University of Tokyo
Hiroshi Yokozaki
Hiroshi Yokozaki Kobe University
Kohei Miyazono
Kohei Miyazono University of Tokyo
Kouhei Tsumoto
Kouhei Tsumoto University of Tokyo
Hideyuki Saya
Hideyuki Saya Fujita Health University
Axel H. E. Müller
Axel H. E. Müller Johannes Gutenberg University of Mainz
You Han Bae
You Han Bae University of Utah
Kazuhiko Ishihara
Kazuhiko Ishihara University of Tokyo

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