World's Best Scientists 2026 revealed!
Kouhei Tsumoto

Kouhei Tsumoto

D-Index & Metrics

Biology and Biochemistry

D-Index
70
Citations
19170
World Ranking
6948
National Ranking
465

Chemistry

D-Index
69
Citations
18621
World Ranking
6137
National Ranking
387

Kouhei Tsumoto publication distribution in Chemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Chemistry in 2026. The highlighted bar marks where Kouhei Tsumoto sits on this spectrum.

61–80 publications: 66 scientists 81–100 publications: 302 scientists 101–120 publications: 623 scientists 121–140 publications: 918 scientists 141–160 publications: 1,218 scientists 161–180 publications: 1,350 scientists 181–200 publications: 1,344 scientists 201–220 publications: 1,281 scientists 221–240 publications: 1,216 scientists 241–260 publications: 1,100 scientists 261–280 publications: 979 scientists 281–300 publications: 939 scientists 301–320 publications: 764 scientists 321–340 publications: 643 scientists 341–360 publications: 628 scientists 361–380 publications: 522 scientists 381–400 publications: 459 scientists 401–420 publications: 397 scientists 421–440 publications: 327 scientists 441–460 publications: 270 scientists 461–480 publications: 265 scientists 481–500 publications: 252 scientists 501–520 publications: 201 scientists 521–540 publications: 185 scientists 541–560 publications: 148 scientists 561–580 publications: 148 scientists 581–600 publications: 132 scientists 601–620 publications: 114 scientists 621–640 publications: 104 scientists 641–660 publications: 91 scientists 661–680 publications: 92 scientists 681–700 publications: 73 scientists 701–720 publications: 57 scientists 721–740 publications: 54 scientists 741–760 publications: 67 scientists 761–780 publications: 45 scientists 781–800 publications: 46 scientists 801–820 publications: 39 scientists 821–840 publications: 32 scientists 841–860 publications: 36 scientists 861–880 publications: 29 scientists 881–900 publications: 26 scientists 901–920 publications: 24 scientists 921–940 publications: 14 scientists 941–960 publications: 23 scientists 961–980 publications: 28 scientists 981–1,000 publications: 15 scientists 1,001–1,020 publications: 29 scientists 1,021–1,040 publications: 12 scientists 1,041–1,060 publications: 19 scientists 1,061–1,080 publications: 12 scientists 1,081–1,100 publications: 6 scientists 1,101–1,120 publications: 8 scientists 1,121–1,140 publications: 12 scientists 1,141–1,160 publications: 5 scientists 1,161–1,180 publications: 6 scientists 1,181–1,200 publications: 14 scientists 1,201–1,220 publications: 7 scientists 1,221–1,240 publications: 2 scientists 1,241–1,260 publications: 6 scientists 1,261–1,280 publications: 4 scientists 1,281–1,294 publications: 6 scientists 1,295+ publications: 100 scientists
61 publications 1,295+

This scientist: 609 publications — 93rd percentile

93% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,295 publications or more.

Kouhei Tsumoto D-index placement in Chemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Chemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Kouhei Tsumoto sits on this spectrum.

40–41 D-Index: 289 scientists 42–43 D-Index: 612 scientists 44–45 D-Index: 808 scientists 46–47 D-Index: 776 scientists 48–49 D-Index: 835 scientists 50–51 D-Index: 861 scientists 52–53 D-Index: 872 scientists 54–55 D-Index: 933 scientists 56–57 D-Index: 1,051 scientists 58–59 D-Index: 930 scientists 60–61 D-Index: 882 scientists 62–63 D-Index: 834 scientists 64–65 D-Index: 731 scientists 66–67 D-Index: 775 scientists 68–69 D-Index: 683 scientists 70–71 D-Index: 646 scientists 72–73 D-Index: 561 scientists 74–75 D-Index: 501 scientists 76–77 D-Index: 437 scientists 78–79 D-Index: 388 scientists 80–81 D-Index: 354 scientists 82–83 D-Index: 292 scientists 84–85 D-Index: 275 scientists 86–87 D-Index: 254 scientists 88–89 D-Index: 235 scientists 90–91 D-Index: 185 scientists 92–93 D-Index: 192 scientists 94–95 D-Index: 155 scientists 96–97 D-Index: 163 scientists 98–99 D-Index: 125 scientists 100–101 D-Index: 105 scientists 102–103 D-Index: 105 scientists 104–105 D-Index: 112 scientists 106–107 D-Index: 88 scientists 108–109 D-Index: 68 scientists 110–111 D-Index: 69 scientists 112–113 D-Index: 65 scientists 114–115 D-Index: 79 scientists 116–117 D-Index: 61 scientists 118–119 D-Index: 44 scientists 120–121 D-Index: 37 scientists 122–123 D-Index: 40 scientists 124–125 D-Index: 33 scientists 126–127 D-Index: 26 scientists 128–129 D-Index: 34 scientists 130–131 D-Index: 35 scientists 132–133 D-Index: 25 scientists 134–135 D-Index: 27 scientists 136–137 D-Index: 17 scientists 138–139 D-Index: 16 scientists 140–141 D-Index: 20 scientists 142–143 D-Index: 20 scientists 144–145 D-Index: 15 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 9 scientists 150–151 D-Index: 16 scientists 152–153 D-Index: 11 scientists 154–155 D-Index: 9 scientists 156–157 D-Index: 3 scientists 158 D-Index: 3 scientists 159+ D-Index: 98 scientists
40 D-Index 159+

This scientist: 69 D-Index — 66th percentile

66% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 159 D-Index or more.

Overview

Kouhei Tsumoto is affiliated with the University of Tokyo in Japan and has made contributions primarily within the fields of Biochemistry, Genetics, and Molecular Biology, alongside Medicine. Their work extensively covers subfields including Molecular Biology, Radiology, Nuclear Medicine and Imaging, Immunology, Cell Biology, and Materials Chemistry.

Tsumoto's research topics are focused on Monoclonal and Polyclonal Antibodies Research, Protein purification and stability, Glycosylation and Glycoproteins Research, Protein Structure and Dynamics, Chemical Synthesis and Analysis, Click Chemistry and Applications, and RNA and protein synthesis mechanisms.

They have published numerous papers in various scientific journals. Some recent papers include:

  • "Dual-Sensitive Nanomicelles Enhancing Systemic Delivery of Therapeutically Active Antibodies Specifically into the Brain" (2020), ACS Nano
  • "Current advances in biopharmaceutical informatics: guidelines, impact and challenges in the computational developability assessment of antibody therapeutics" (2022), mAbs
  • "GPC1 specific CAR-T cells eradicate established solid tumor without adverse effects and synergize with anti-PD-1 Ab" (2020), eLife
  • "Histone H3 lysine 27 crotonylation mediates gene transcriptional repression in chromatin" (2023), Molecular Cell
  • "Engineering Stability, Viscosity, and Immunogenicity of Antibodies by Computational Design" (2020), Journal of Pharmaceutical Sciences

Frequent co-authors working alongside Tsumoto include Satoru Nagatoishi, Makoto Nakakido, Daisuke Kuroda, José M. M. Caaveiro, and Hiroki Akiba.

Common venues where Tsumoto publishes include Scientific Reports, bioRxiv (Cold Spring Harbor Laboratory), Journal of Biological Chemistry, Biochemical and Biophysical Research Communications, and Protein Science.

Best Publications

  • Suppression of protein interactions by arginine: a proposed mechanism of the arginine effects.

    Tsutomu Arakawa;Daisuke Ejima;Kouhei Tsumoto;Noriyuki Obeyama

  • Human inhibitory receptors Ig-like transcript 2 (ILT2) and ILT4 compete with CD8 for MHC class I binding and bind preferentially to HLA-G

    Mitsunori Shiroishi;Kouhei Tsumoto;Kimie Amano;Yasuo Shirakihara

  • Fucose Depletion from Human IgG1 Oligosaccharide Enhances Binding Enthalpy and Association Rate Between IgG1 and FcγRIIIa

    Akira Okazaki;Emi Shoji-Hosaka;Kazuyasu Nakamura;Masako Wakitani

  • Role of Arginine in Protein Refolding, Solubilization, and Purification

    Kouhei Tsumoto;Mitsuo Umetsu;Izumi Kumagai;Daisuke Ejima

  • Practical considerations in refolding proteins from inclusion bodies

    Kouhei Tsumoto;Daisuke Ejima;Izumi Kumagai;Tsutomu Arakawa

  • The effects of arginine on refolding of aggregated proteins: not facilitate refolding, but suppress aggregation.

    Tsutomu Arakawa;Kouhei Tsumoto

  • Structural basis for recognition of the nonclassical MHC molecule HLA-G by the leukocyte Ig-like receptor B2 (LILRB2/LIR2/ILT4/CD85d)

    Mitsunori Shiroishi;Kimiko Kuroki;Linda Rasubala;Kouhei Tsumoto

  • Biotechnology applications of amino acids in protein purification and formulations.

    T. Arakawa;K. Tsumoto;Y. Kita;B. Chang

  • Highly efficient recovery of functional single-chain Fv fragments from inclusion bodies overexpressed in Escherichia coli by controlled introduction of oxidizing reagent--application to a human single-chain Fv fragment.

    Kouhei Tsumoto;Katsutoshi Shinoki;Hidemasa Kondo;Makoto Uchikawa

  • Bioassisted Room‐Temperature Immobilization and Mineralization of Zinc Oxide—The Structural Ordering of ZnO Nanoparticles into a Flower‐Type Morphology

    Mitsuo Umetsu;Masamichi Mizuta;Kouhei Tsumoto;Satoshi Ohara

  • How additives influence the refolding of immunoglobulin-folded proteins in a stepwise dialysis system. Spectroscopic evidence for highly efficient refolding of a single-chain Fv fragment.

    Mitsuo Umetsu;Kouhei Tsumoto;Masaki Hara;Kumar Ashish

  • Efficient Leukocyte Ig-like Receptor Signaling and Crystal Structure of Disulfide-linked HLA-G Dimer

    Mitsunori Shiroishi;Kimiko Kuroki;Toyoyuki Ose;Linda Rasubala

  • Structural basis for self-assembly of a cytolytic pore lined by protein and lipid

    Koji Tanaka;Jose Manuel Martinez Caaveiro;Koldo Morante;Juan Manuel González-Manãs

  • Effects of acid exposure on the conformation, stability, and aggregation of monoclonal antibodies.

    Daisuke Ejima;Kouhei Tsumoto;Harumi Fukada;Ryosuke Yumioka

  • Next Generation Drying Technologies for Pharmaceutical Applications

    Robert H. Walters;Bakul Bhatnagar;Serguei Tchessalov;Ken-Ichi Izutsu

  • Elution of antibodies from a Protein-A column by aqueous arginine solutions.

    Tsutomu Arakawa;John S Philo;Kouhei Tsumoto;Ryosuke Yumioka

  • Arginine as an effective additive in gel permeation chromatography.

    Daisuke Ejima;Ryosuke Yumioka;Tsutomu Arakawa;Kouhei Tsumoto

  • Solubilization of active green fluorescent protein from insoluble particles by guanidine and arginine.

    Kouhei Tsumoto;Mitsuo Umetsu;Izumi Kumagai;Daisuke Ejima

  • Small molecule pharmacological chaperones: From thermodynamic stabilization to pharmaceutical drugs.

    Tsutomu Arakawa;Daisuke Ejima;Yoshiko Kita;Kouhei Tsumoto

  • Open sandwich ELISA: a novel immunoassay based on the interchain interaction of antibody variable region

    Hiroshi Ueda;Kouhei Tsumoto;Kazuishi Kubota;Eiji Suzuki

  • Effective elution of antibodies by arginine and arginine derivatives in affinity column chromatography.

    Daisuke Ejima;Ryosuke Yumioka;Kouhei Tsumoto;Tsutomu Arakawa

Frequent Co-Authors

Izumi Kumagai
Izumi Kumagai Tokyo University of Agriculture and Technology
Yoshikazu Tanaka
Yoshikazu Tanaka Tohoku University
Takao Hamakubo
Takao Hamakubo Nippon Medical School
Teruyuki Nagamune
Teruyuki Nagamune University of Tokyo
Kentaro Shimizu
Kentaro Shimizu University of Zurich
Isao Tanaka
Isao Tanaka Hokkaido University
Min Yao
Min Yao Hokkaido University
Katsumi Maenaka
Katsumi Maenaka Hokkaido University
Makoto Kuroda
Makoto Kuroda National Institutes of Health
Tadafumi Adschiri
Tadafumi Adschiri Tohoku University

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