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Kouhei Tsumoto

Kouhei Tsumoto

University of Tokyo
Japan

D-Index & Metrics

Discipline name D-Index World Ranking Current World Ranking National Ranking Current National Ranking Publications Citations
Chemistry 69 6137 5568 387 363 609 18621
Biology and Biochemistry 70 6947 6408 464 434 628 19170

Kouhei Tsumoto publications per year

The chart shows the history of publications by Kouhei Tsumoto between 1992 and 2025, highlighting the no. of papers published in each year and offering an overview of the publication velocity of this scholar. Kouhei Tsumoto published across 34 years, from 1992 to 2025, averaging 21.3 papers a year. Output peaked at 46 publications in 2015. 50 of the 725 publications appeared in the last two years.

No. of publications
10 20 30 40
Bar chart. Horizontal axis: year, 1992 to 2025. Vertical axis: number of publications, 0 to 46. Peak 46 publications in 2015. 1992: 1 publication 1993: 0 publications 1994: 3 publications 1995: 2 publications 1996: 3 publications 1997: 3 publications 1998: 4 publications 1999: 13 publications 2000: 13 publications 2001: 19 publications 2002: 15 publications 2003: 21 publications 2004: 27 publications 2005: 17 publications 2006: 18 publications 2007: 35 publications 2008: 29 publications 2009: 17 publications 2010: 22 publications 2011: 19 publications 2012: 16 publications 2013: 27 publications 2014: 30 publications 2015: 46 publications 2016: 33 publications 2017: 30 publications 2018: 35 publications 2019: 30 publications 2020: 32 publications 2021: 42 publications 2022: 33 publications 2023: 40 publications 2024: 28 publications 2025: 22 publications
1992 2025

725 publications in total across all disciplines

View publications per year as a table
Kouhei Tsumoto: publications per year, 1992 to 2025
Year Publications
1992 1
1993 0
1994 3
1995 2
1996 3
1997 3
1998 4
1999 13
2000 13
2001 19
2002 15
2003 21
2004 27
2005 17
2006 18
2007 35
2008 29
2009 17
2010 22
2011 19
2012 16
2013 27
2014 30
2015 46
2016 33
2017 30
2018 35
2019 30
2020 32
2021 42
2022 33
2023 40
2024 28
2025 22
Total 725
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Kouhei Tsumoto publication distribution in Chemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Chemistry in 2026. The highlighted bar marks where Kouhei Tsumoto sits on this spectrum.

No. of scientists
250 500 750 1,000 1,250
Bar chart with 63 bars. Horizontal axis: publications, 61–80 to 1,295+. Vertical axis: number of scientists, 0 to 1,350. Most scientists, 1,350, have 161–180 publications. The last bar groups every scientist with 1,295 publications or more. The highlighted bar, 601–620 publications, is where this scientist sits. 61–80 publications: 66 scientists 81–100 publications: 302 scientists 101–120 publications: 623 scientists 121–140 publications: 918 scientists 141–160 publications: 1,218 scientists 161–180 publications: 1,350 scientists 181–200 publications: 1,344 scientists 201–220 publications: 1,281 scientists 221–240 publications: 1,216 scientists 241–260 publications: 1,100 scientists 261–280 publications: 979 scientists 281–300 publications: 939 scientists 301–320 publications: 764 scientists 321–340 publications: 643 scientists 341–360 publications: 628 scientists 361–380 publications: 522 scientists 381–400 publications: 459 scientists 401–420 publications: 397 scientists 421–440 publications: 327 scientists 441–460 publications: 270 scientists 461–480 publications: 265 scientists 481–500 publications: 252 scientists 501–520 publications: 201 scientists 521–540 publications: 185 scientists 541–560 publications: 148 scientists 561–580 publications: 148 scientists 581–600 publications: 132 scientists 601–620 publications: 114 scientists 621–640 publications: 104 scientists 641–660 publications: 91 scientists 661–680 publications: 92 scientists 681–700 publications: 73 scientists 701–720 publications: 57 scientists 721–740 publications: 54 scientists 741–760 publications: 67 scientists 761–780 publications: 45 scientists 781–800 publications: 46 scientists 801–820 publications: 39 scientists 821–840 publications: 32 scientists 841–860 publications: 36 scientists 861–880 publications: 29 scientists 881–900 publications: 26 scientists 901–920 publications: 24 scientists 921–940 publications: 14 scientists 941–960 publications: 23 scientists 961–980 publications: 28 scientists 981–1,000 publications: 15 scientists 1,001–1,020 publications: 29 scientists 1,021–1,040 publications: 12 scientists 1,041–1,060 publications: 19 scientists 1,061–1,080 publications: 12 scientists 1,081–1,100 publications: 6 scientists 1,101–1,120 publications: 8 scientists 1,121–1,140 publications: 12 scientists 1,141–1,160 publications: 5 scientists 1,161–1,180 publications: 6 scientists 1,181–1,200 publications: 14 scientists 1,201–1,220 publications: 7 scientists 1,221–1,240 publications: 2 scientists 1,241–1,260 publications: 6 scientists 1,261–1,280 publications: 4 scientists 1,281–1,294 publications: 6 scientists 1,295+ publications: 100 scientists
61–80 publications 1,295+

This scientist: 609 publications — 93rd percentile

93% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,295 publications or more.

View publications distribution as a table
Number of Chemistry scientists by publication count, Research.com 2026 ranking edition. Based on 17,934 ranked scientists.
Publications Scientists This scientist
61–80 66
81–100 302
101–120 623
121–140 918
141–160 1,218
161–180 1,350
181–200 1,344
201–220 1,281
221–240 1,216
241–260 1,100
261–280 979
281–300 939
301–320 764
321–340 643
341–360 628
361–380 522
381–400 459
401–420 397
421–440 327
441–460 270
461–480 265
481–500 252
501–520 201
521–540 185
541–560 148
561–580 148
581–600 132
601–620 114 609
621–640 104
641–660 91
661–680 92
681–700 73
701–720 57
721–740 54
741–760 67
761–780 45
781–800 46
801–820 39
821–840 32
841–860 36
861–880 29
881–900 26
901–920 24
921–940 14
941–960 23
961–980 28
981–1,000 15
1,001–1,020 29
1,021–1,040 12
1,041–1,060 19
1,061–1,080 12
1,081–1,100 6
1,101–1,120 8
1,121–1,140 12
1,141–1,160 5
1,161–1,180 6
1,181–1,200 14
1,201–1,220 7
1,221–1,240 2
1,241–1,260 6
1,261–1,280 4
1,281–1,294 6
1,295+ 100
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Kouhei Tsumoto D-index placement in Chemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Chemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Kouhei Tsumoto sits on this spectrum.

No. of scientists
250 500 750 1,000
Bar chart with 61 bars. Horizontal axis: D-Index, 40–41 to 159+. Vertical axis: number of scientists, 0 to 1,051. Most scientists, 1,051, have 56–57 D-Index. The last bar groups every scientist with 159 D-Index or more. The highlighted bar, 68–69 D-Index, is where this scientist sits. 40–41 D-Index: 289 scientists 42–43 D-Index: 612 scientists 44–45 D-Index: 808 scientists 46–47 D-Index: 776 scientists 48–49 D-Index: 835 scientists 50–51 D-Index: 861 scientists 52–53 D-Index: 872 scientists 54–55 D-Index: 933 scientists 56–57 D-Index: 1,051 scientists 58–59 D-Index: 930 scientists 60–61 D-Index: 882 scientists 62–63 D-Index: 834 scientists 64–65 D-Index: 731 scientists 66–67 D-Index: 775 scientists 68–69 D-Index: 683 scientists 70–71 D-Index: 646 scientists 72–73 D-Index: 561 scientists 74–75 D-Index: 501 scientists 76–77 D-Index: 437 scientists 78–79 D-Index: 388 scientists 80–81 D-Index: 354 scientists 82–83 D-Index: 292 scientists 84–85 D-Index: 275 scientists 86–87 D-Index: 254 scientists 88–89 D-Index: 235 scientists 90–91 D-Index: 185 scientists 92–93 D-Index: 192 scientists 94–95 D-Index: 155 scientists 96–97 D-Index: 163 scientists 98–99 D-Index: 125 scientists 100–101 D-Index: 105 scientists 102–103 D-Index: 105 scientists 104–105 D-Index: 112 scientists 106–107 D-Index: 88 scientists 108–109 D-Index: 68 scientists 110–111 D-Index: 69 scientists 112–113 D-Index: 65 scientists 114–115 D-Index: 79 scientists 116–117 D-Index: 61 scientists 118–119 D-Index: 44 scientists 120–121 D-Index: 37 scientists 122–123 D-Index: 40 scientists 124–125 D-Index: 33 scientists 126–127 D-Index: 26 scientists 128–129 D-Index: 34 scientists 130–131 D-Index: 35 scientists 132–133 D-Index: 25 scientists 134–135 D-Index: 27 scientists 136–137 D-Index: 17 scientists 138–139 D-Index: 16 scientists 140–141 D-Index: 20 scientists 142–143 D-Index: 20 scientists 144–145 D-Index: 15 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 9 scientists 150–151 D-Index: 16 scientists 152–153 D-Index: 11 scientists 154–155 D-Index: 9 scientists 156–157 D-Index: 3 scientists 158 D-Index: 3 scientists 159+ D-Index: 98 scientists
40–41 D-Index 159+

This scientist: 69 D-Index — 66th percentile

66% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 159 D-Index or more.

View D-Index distribution as a table
Number of Chemistry scientists by D-index, Research.com 2026 ranking edition. Based on 17,934 ranked scientists.
D-Index Scientists This scientist
40–41 289
42–43 612
44–45 808
46–47 776
48–49 835
50–51 861
52–53 872
54–55 933
56–57 1,051
58–59 930
60–61 882
62–63 834
64–65 731
66–67 775
68–69 683 69
70–71 646
72–73 561
74–75 501
76–77 437
78–79 388
80–81 354
82–83 292
84–85 275
86–87 254
88–89 235
90–91 185
92–93 192
94–95 155
96–97 163
98–99 125
100–101 105
102–103 105
104–105 112
106–107 88
108–109 68
110–111 69
112–113 65
114–115 79
116–117 61
118–119 44
120–121 37
122–123 40
124–125 33
126–127 26
128–129 34
130–131 35
132–133 25
134–135 27
136–137 17
138–139 16
140–141 20
142–143 20
144–145 15
146–147 9
148–149 9
150–151 16
152–153 11
154–155 9
156–157 3
158 3
159+ 98
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Overview

Kouhei Tsumoto is affiliated with the University of Tokyo in Japan and has made contributions primarily within the fields of Biochemistry, Genetics, and Molecular Biology, alongside Medicine. Their work extensively covers subfields including Molecular Biology, Radiology, Nuclear Medicine and Imaging, Immunology, Cell Biology, and Materials Chemistry.

Tsumoto's research topics are focused on Monoclonal and Polyclonal Antibodies Research, Protein purification and stability, Glycosylation and Glycoproteins Research, Protein Structure and Dynamics, Chemical Synthesis and Analysis, Click Chemistry and Applications, and RNA and protein synthesis mechanisms.

They have published numerous papers in various scientific journals. Some recent papers include:

  • "Dual-Sensitive Nanomicelles Enhancing Systemic Delivery of Therapeutically Active Antibodies Specifically into the Brain" (2020), ACS Nano
  • "Current advances in biopharmaceutical informatics: guidelines, impact and challenges in the computational developability assessment of antibody therapeutics" (2022), mAbs
  • "GPC1 specific CAR-T cells eradicate established solid tumor without adverse effects and synergize with anti-PD-1 Ab" (2020), eLife
  • "Histone H3 lysine 27 crotonylation mediates gene transcriptional repression in chromatin" (2023), Molecular Cell
  • "Engineering Stability, Viscosity, and Immunogenicity of Antibodies by Computational Design" (2020), Journal of Pharmaceutical Sciences

Frequent co-authors working alongside Tsumoto include Satoru Nagatoishi, Makoto Nakakido, Daisuke Kuroda, José M. M. Caaveiro, and Hiroki Akiba.

Common venues where Tsumoto publishes include Scientific Reports, bioRxiv (Cold Spring Harbor Laboratory), Journal of Biological Chemistry, Biochemical and Biophysical Research Communications, and Protein Science.

Best Publications

  • Suppression of protein interactions by arginine: a proposed mechanism of the arginine effects.

    Tsutomu Arakawa;Daisuke Ejima;Kouhei Tsumoto;Noriyuki Obeyama

  • Human inhibitory receptors Ig-like transcript 2 (ILT2) and ILT4 compete with CD8 for MHC class I binding and bind preferentially to HLA-G

    Mitsunori Shiroishi;Kouhei Tsumoto;Kimie Amano;Yasuo Shirakihara

  • Fucose Depletion from Human IgG1 Oligosaccharide Enhances Binding Enthalpy and Association Rate Between IgG1 and FcγRIIIa

    Akira Okazaki;Emi Shoji-Hosaka;Kazuyasu Nakamura;Masako Wakitani

  • Role of Arginine in Protein Refolding, Solubilization, and Purification

    Kouhei Tsumoto;Mitsuo Umetsu;Izumi Kumagai;Daisuke Ejima

  • Practical considerations in refolding proteins from inclusion bodies

    Kouhei Tsumoto;Daisuke Ejima;Izumi Kumagai;Tsutomu Arakawa

  • The effects of arginine on refolding of aggregated proteins: not facilitate refolding, but suppress aggregation.

    Tsutomu Arakawa;Kouhei Tsumoto

  • Structural basis for recognition of the nonclassical MHC molecule HLA-G by the leukocyte Ig-like receptor B2 (LILRB2/LIR2/ILT4/CD85d)

    Mitsunori Shiroishi;Kimiko Kuroki;Linda Rasubala;Kouhei Tsumoto

  • Biotechnology applications of amino acids in protein purification and formulations.

    T. Arakawa;K. Tsumoto;Y. Kita;B. Chang

  • Highly efficient recovery of functional single-chain Fv fragments from inclusion bodies overexpressed in Escherichia coli by controlled introduction of oxidizing reagent--application to a human single-chain Fv fragment.

    Kouhei Tsumoto;Katsutoshi Shinoki;Hidemasa Kondo;Makoto Uchikawa

  • Bioassisted Room‐Temperature Immobilization and Mineralization of Zinc Oxide—The Structural Ordering of ZnO Nanoparticles into a Flower‐Type Morphology

    Mitsuo Umetsu;Masamichi Mizuta;Kouhei Tsumoto;Satoshi Ohara

  • How additives influence the refolding of immunoglobulin-folded proteins in a stepwise dialysis system. Spectroscopic evidence for highly efficient refolding of a single-chain Fv fragment.

    Mitsuo Umetsu;Kouhei Tsumoto;Masaki Hara;Kumar Ashish

  • Efficient Leukocyte Ig-like Receptor Signaling and Crystal Structure of Disulfide-linked HLA-G Dimer

    Mitsunori Shiroishi;Kimiko Kuroki;Toyoyuki Ose;Linda Rasubala

  • Structural basis for self-assembly of a cytolytic pore lined by protein and lipid

    Koji Tanaka;Jose Manuel Martinez Caaveiro;Koldo Morante;Juan Manuel González-Manãs

  • Effects of acid exposure on the conformation, stability, and aggregation of monoclonal antibodies.

    Daisuke Ejima;Kouhei Tsumoto;Harumi Fukada;Ryosuke Yumioka

  • Next Generation Drying Technologies for Pharmaceutical Applications

    Robert H. Walters;Bakul Bhatnagar;Serguei Tchessalov;Ken-Ichi Izutsu

  • Elution of antibodies from a Protein-A column by aqueous arginine solutions.

    Tsutomu Arakawa;John S Philo;Kouhei Tsumoto;Ryosuke Yumioka

  • Arginine as an effective additive in gel permeation chromatography.

    Daisuke Ejima;Ryosuke Yumioka;Tsutomu Arakawa;Kouhei Tsumoto

  • Solubilization of active green fluorescent protein from insoluble particles by guanidine and arginine.

    Kouhei Tsumoto;Mitsuo Umetsu;Izumi Kumagai;Daisuke Ejima

  • Small molecule pharmacological chaperones: From thermodynamic stabilization to pharmaceutical drugs.

    Tsutomu Arakawa;Daisuke Ejima;Yoshiko Kita;Kouhei Tsumoto

  • Open sandwich ELISA: a novel immunoassay based on the interchain interaction of antibody variable region

    Hiroshi Ueda;Kouhei Tsumoto;Kazuishi Kubota;Eiji Suzuki

  • Effective elution of antibodies by arginine and arginine derivatives in affinity column chromatography.

    Daisuke Ejima;Ryosuke Yumioka;Kouhei Tsumoto;Tsutomu Arakawa

Frequent Co-Authors

Izumi Kumagai
Izumi Kumagai Tokyo University of Agriculture and Technology
Yoshikazu Tanaka
Yoshikazu Tanaka Tohoku University
Takao Hamakubo
Takao Hamakubo Nippon Medical School
Teruyuki Nagamune
Teruyuki Nagamune University of Tokyo
Kentaro Shimizu
Kentaro Shimizu University of Zurich
Isao Tanaka
Isao Tanaka Hokkaido University
Min Yao
Min Yao Hokkaido University
Katsumi Maenaka
Katsumi Maenaka Hokkaido University
Makoto Kuroda
Makoto Kuroda National Institutes of Health
Tadafumi Adschiri
Tadafumi Adschiri Tohoku University

External Links

Personal website of Kouhei Tsumoto

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Best Scientists Citing Kouhei Tsumoto

Izumi Kumagai

Izumi Kumagai

Tokyo University of Agriculture and Technology

Publications: 65

Teruyuki Nagamune

Teruyuki Nagamune

University of Tokyo

Publications: 38

Susumu Uchiyama

Susumu Uchiyama

Osaka University

Publications: 35

Katsumi Maenaka

Katsumi Maenaka

Hokkaido University

Publications: 34

Nathalie Rouas-Freiss

Nathalie Rouas-Freiss

French Alternative Energies and Atomic Energy Commission (CEA)

Publications: 28

Joel LeMaoult

Joel LeMaoult

Université Paris Cité

Publications: 28

Edgardo D. Carosella

Edgardo D. Carosella

Université Paris Cité

Publications: 25

Koichi Kato

Koichi Kato

National Institutes of Natural Sciences

Publications: 23

Mitsuo Satoh

Mitsuo Satoh

Kyowa Kirin (Japan)

Publications: 22

Kunihiro Kuwajima

Kunihiro Kuwajima

Tokyo University of Science

Publications: 20

Kenya Shitara

Kenya Shitara

Kyowa Kirin (Japan)

Publications: 17

Takuzo Aida

Takuzo Aida

University of Tokyo

Publications: 16

Chandra S. Verma

Chandra S. Verma

Agency for Science, Technology and Research

Publications: 15

Vera Rebmann

Vera Rebmann

Essen University Hospital

Publications: 15

Hisashi Arase

Hisashi Arase

Osaka University

Publications: 15

Robert T. Clubb

Robert T. Clubb

University of California, Los Angeles

Publications: 15

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