D-Index & Metrics Best Publications
Chemistry
Japan
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Chemistry D-index 91 Citations 26,858 254 World Ranking 1120 National Ranking 60

Research.com Recognitions

Awards & Achievements

2023 - Research.com Chemistry in Japan Leader Award

Overview

What is he best known for?

The fields of study Nobuhiro Nishiyama is best known for:

  • Enzyme
  • Gene
  • Cancer

With his scientific publications, his incorporates both Biochemistry and Cell biology. In his works, he performs multidisciplinary study on Cell biology and Biochemistry. He incorporates Organic chemistry and Combinatorial chemistry in his research. Nobuhiro Nishiyama merges Combinatorial chemistry with Organic chemistry in his study. He undertakes multidisciplinary investigations into Biophysics and Nanotechnology in his work. While working on this project, he studies both Nanotechnology and Biophysics. Nobuhiro Nishiyama merges Micelle with Copolymer in his study. Nobuhiro Nishiyama integrates several fields in his works, including Copolymer and Micelle. His research combines Physical chemistry and Aqueous solution.

His most cited work include:

  • Preparation and Biological Characterization of Polymeric Micelle Drug Carriers with Intracellular pH-Triggered Drug Release Property: Tumor Permeability, Controlled Subcellular Drug Distribution, and Enhanced in Vivo Antitumor Efficacy (667 citations)
  • Lactosylated Poly(ethylene glycol)-siRNA Conjugate through Acid-Labile β-Thiopropionate Linkage to Construct pH-Sensitive Polyion Complex Micelles Achieving Enhanced Gene Silencing in Hepatoma Cells (440 citations)
  • Multifunctional polymeric micelles with folate-mediated cancer cell targeting and pH-triggered drug releasing properties for active intracellular drug delivery (399 citations)

What are the main themes of his work throughout his whole career to date

His work in Organic chemistry is not limited to one particular discipline; it also encompasses Ethylene glycol. His research brings together the fields of Organic chemistry and Ethylene glycol. In his works, he conducts interdisciplinary research on Biochemistry and Cell biology. In his articles, Nobuhiro Nishiyama combines various disciplines, including Cell biology and Biochemistry. Nobuhiro Nishiyama combines Biophysics and Nanotechnology in his research. He conducts interdisciplinary study in the fields of Nanotechnology and Biophysics through his research. His Aqueous solution study frequently draws connections to adjacent fields such as Micelle. In most of his Micelle studies, his work intersects topics such as Aqueous solution. Nobuhiro Nishiyama merges Gene with Small interfering RNA in his research.

Nobuhiro Nishiyama most often published in these fields:

  • Organic chemistry (57.46%)
  • Biochemistry (53.95%)
  • Biophysics (40.79%)

What were the highlights of his more recent work (between 2018-2021)?

  • Organic chemistry (75.00%)
  • Biochemistry (56.25%)
  • Polymer (43.75%)

In recent works Nobuhiro Nishiyama was focusing on the following fields of study:

Nobuhiro Nishiyama integrates many fields, such as Internal medicine and engineering, in his works. He undertakes multidisciplinary investigations into Pathology and Internal medicine in his work. Cancer research and Pancreatic cancer are fields of study that intersect with his Cancer study. Nobuhiro Nishiyama combines Cancer research and Cancer in his research. His Gene study falls within the topics of Small interfering RNA and Transfection. His research ties Moiety and Organic chemistry together. Nobuhiro Nishiyama integrates Biochemistry with Biophysics in his study. Nobuhiro Nishiyama performs integrative Polymer and Lower critical solution temperature research in his work. Nobuhiro Nishiyama undertakes interdisciplinary study in the fields of Combinatorial chemistry and Organic chemistry through his research.

Between 2018 and 2021, his most popular works were:

  • Poly(vinyl alcohol) boosting therapeutic potential of p -boronophenylalanine in neutron capture therapy by modulating metabolism (53 citations)
  • In vivo rendezvous of small nucleic acid drugs with charge-matched block catiomers to target cancers (40 citations)
  • Sonodynamic Therapy With Anticancer Micelles and High-Intensity Focused Ultrasound in Treatment of Canine Cancer (31 citations)

In his most recent research, the most cited works focused on:

  • DNA
  • Luciferase
  • Luciferin

The research on Prostate cancer and Pancreatic cancer is part of his Cancer project. In his works, Nobuhiro Nishiyama conducts interdisciplinary research on Biochemistry and Pharmacology. He undertakes multidisciplinary investigations into Pharmacology and Biochemistry in his work. His Internal medicine study frequently intersects with other fields, such as Adverse effect. He merges Adverse effect with Cancer in his research. While working on this project, Nobuhiro Nishiyama studies both Organic chemistry and Alcohol. Nobuhiro Nishiyama performs multidisciplinary study in the fields of Alcohol and Organic chemistry via his papers. In his works, he performs multidisciplinary study on Gene and In vivo. He combines In vivo and Gene in his research.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size

H. Cabral;Y. Matsumoto;K. Mizuno;Q. Chen.
Nature Nanotechnology (2011)

2138 Citations

Current state, achievements, and future prospects of polymeric micelles as nanocarriers for drug and gene delivery.

Nobuhiro Nishiyama;Kazunori Kataoka.
Pharmacology & Therapeutics (2006)

1192 Citations

Novel Cisplatin-Incorporated Polymeric Micelles Can Eradicate Solid Tumors in Mice

Nobuhiro Nishiyama;Souichiro Okazaki;Horacio Cabral;Masaki Miyamoto.
Cancer Research (2003)

728 Citations

Lactosylated poly(ethylene glycol)-sIRNA conjugate through acid-labile β-thiopropionate linkage to construct pH-sensitive polyion complex micelles achieving enhanced gene silencing in hepatoma cells

Motoi Oishi;Yukio Nagasaki;Keiji Itaka;Nobuhiro Nishiyama.
Journal of the American Chemical Society (2005)

680 Citations

Preparation and biological characterization of polymeric micelle drug carriers with intracellular pH-triggered drug release property: tumor permeability, controlled subcellular drug distribution, and enhanced in vivo antitumor efficacy.

Younsoo Bae;Nobuhiro Nishiyama;Shigeto Fukushima;Hiroyuki Koyama.
Bioconjugate Chemistry (2005)

648 Citations

Multifunctional polymeric micelles with folate-mediated cancer cell targeting and pH-triggered drug releasing properties for active intracellular drug delivery

Younsoo Bae;Woo Dong Jang;Nobuhiro Nishiyama;Shigeto Fukushima.
Molecular BioSystems (2005)

524 Citations

Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-β signaling

Mitsunobu R. Kano;Younsoo Bae;Caname Iwata;Yasuyuki Morishita.
Proceedings of the National Academy of Sciences of the United States of America (2007)

458 Citations

Block catiomer polyplexes with regulated densities of charge and disulfide cross-linking directed to enhance gene expression.

Kanjiro Miyata;Yoshinori Kakizawa;Nobuhiro Nishiyama;Atsushi Harada.
Journal of the American Chemical Society (2004)

457 Citations

Rational design of smart supramolecular assemblies for gene delivery: Chemical challenges in the creation of artificial viruses

Kanjiro Miyata;Nobuhiro Nishiyama;Kazunori Kataoka.
Chemical Society Reviews (2012)

456 Citations

Cisplatin-incorporating polymeric micelles (NC-6004) can reduce nephrotoxicity and neurotoxicity of cisplatin in rats

H Uchino;Y Matsumura;T Negishi;F Koizumi.
British Journal of Cancer (2005)

448 Citations

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