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Immunology

D-Index
61
Citations
13449
World Ranking
3234
National Ranking
1510

Overview

Tibor Keler is affiliated with Bristol-Myers Squibb in the United States. Their research primarily focuses on medicine, with significant contributions to immunology and microbiology. Keler's work is especially concentrated on oncology and immunology as subfields, with additional involvement in radiology, nuclear medicine, imaging, pulmonary and respiratory medicine, and molecular biology.

Throughout Keler's career, their research topics have included:

  • Cancer Immunotherapy and Biomarkers
  • Immunotherapy and Immune Responses
  • CAR-T Cell Therapy Research
  • Monoclonal and Polyclonal Antibodies Research
  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • Mast Cells and Histamine

Keler has published in various scientific venues, with frequent publications appearing in:

  • Regular and Young Investigator Award Abstracts
  • Cancer Research
  • Allergy
  • Journal of Clinical Oncology
  • Clinical Cancer Research

Notable recent papers include:

  • "Rindopepimut with Bevacizumab for Patients with Relapsed EGFRvIII-Expressing Glioblastoma (ReACT): Results of a Double-Blind Randomized Phase II Trial," published in Clinical Cancer Research (2020)
  • "Overcoming primary and acquired resistance to anti-PD-L1 therapy by induction and activation of tumor-residing cDC1s," published in Nature Communications (2020)
  • "Flt3 ligand augments immune responses to anti-DEC-205-NY-ESO-1 vaccine through expansion of dendritic cell subsets," published in Nature Cancer (2020)
  • "Safety and activity of varlilumab, a novel and first-in-class agonist anti-CD27 antibody, for hematologic malignancies," published in Blood Advances (2020)
  • "Anti-KIT monoclonal antibody CDX-0159 induces profound and durable mast cell suppression in a healthy volunteer study," published in Allergy (2022)

Frequent coauthors collaborating with Keler include:

  • Michael Yellin
  • Laura Vitale
  • Diego Alvarado
  • Lawrence J. Thomas
  • Henry C. Marsh

Best Publications

  • Viraemia suppressed in HIV-1-infected humans by broadly neutralizing antibody 3BNC117

    Marina Caskey;Florian Klein;Julio C. C. Lorenzi;Michael S. Seaman

  • Autoimmunity in a Phase I Trial of a Fully Human Anti-Cytotoxic T-Lymphocyte Antigen-4 Monoclonal Antibody With Multiple Melanoma Peptides and Montanide ISA 51 for Patients With Resected Stages III and IV Melanoma

    Kristin Sanderson;Ronald Scotland;Peter Lee;Dongxin Liu

  • HIV-1 antibody 3BNC117 suppresses viral rebound in humans during treatment interruption

    Johannes F. Scheid;Johannes F. Scheid;Joshua A. Horwitz;Yotam Bar-On;Edward F. Kreider

  • Antibody 10-1074 suppresses viremia in HIV-1-infected individuals

    Marina Caskey;Till Schoofs;Henning Gruell;Allison Settler

  • A phase II, multicenter trial of rindopepimut (CDX-110) in newly diagnosed glioblastoma: the ACT III study

    James Schuster;Rose K. Lai;Rose K. Lai;Lawrence D. Recht;David A. Reardon;David A. Reardon

  • Induction of Antigen-Specific Immunity with a Vaccine Targeting NY-ESO-1 to the Dendritic Cell Receptor DEC-205

    Madhav V. Dhodapkar;Mario Sznol;Biwei Zhao;Ding Wang

  • Phase I/II Study of an Anti-CD30 Monoclonal Antibody (MDX-060) in Hodgkin's Lymphoma and Anaplastic Large-Cell Lymphoma

    Stephen M. Ansell;Steven M. Horwitz;Andreas Engert;Khuda Dad Khan

  • High-Dimensional Phenotypic Mapping of Human Dendritic Cells Reveals Interindividual Variation and Tissue Specialization.

    Marcela Alcántara-Hernández;Rebecca Leylek;Lisa E. Wagar;Edgar G. Engleman

  • Internalization and endosomal degradation of receptor-bound antigens regulate the efficiency of cross presentation by human dendritic cells.

    Bithi Chatterjee;Bithi Chatterjee;Anna Smed-Sörensen;Anna Smed-Sörensen;Lillian Cohn;Cécile Chalouni

  • Mannose receptor-targeted vaccines

    Tibor Keler;Venky Ramakrishna;Michael W Fanger

  • Human monoclonal antibodies to her2/neu

    Tibor Keler;Yashwant Deo

  • Circulating precursors of human CD1c+ and CD141+ dendritic cells

    Gaëlle Breton;Jaeyop Lee;Yu Jerry Zhou;Joseph J. Schreiber

  • Antigen delivery to early endosomes eliminates the superiority of human blood BDCA3+ dendritic cells at cross presentation

    Lillian Cohn;Bithi Chatterjee;Filipp Esselborn;Anna Smed-Sörensen;Anna Smed-Sörensen

  • Dendritic cell‐targeted protein vaccines: a novel approach to induce T‐cell immunity

    C. Trumpfheller;M. P. Longhi;M. Caskey;J. Idoyaga

  • Activity and Safety of CTLA-4 Blockade Combined with Vaccines in Cynomolgus Macaques

    Tibor Keler;Ed Halk;Laura Vitale;Tom O’Neill

  • Antigenic targeting of the human mannose receptor induces tumor immunity.

    Li-Zhen He;Andrea Crocker;Janine Lee;Jose Mendoza-Ramirez

  • Poly(I:C) is an effective adjuvant for antibody and multi-functional CD4+ T cell responses to Plasmodium falciparum circumsporozoite protein (CSP) and αDEC-CSP in non human primates

    Kavita Tewari;Barbara J. Flynn;Silvia B. Boscardin;Kathrin Kastenmueller

  • Improved cellular and humoral immune responses in vivo following targeting of HIV Gag to dendritic cells within human anti–human DEC205 monoclonal antibody

    Cheolho Cheong;Jae Hoon Choi;Laura Vitale;Li Zhen He

  • Mannose Receptor Targeting of Tumor Antigen pmel17 to Human Dendritic Cells Directs Anti-Melanoma T Cell Responses via Multiple HLA Molecules

    Venky Ramakrishna;John F. Treml;Laura Vitale;John E. Connolly

  • Phase I Study Utilizing a Novel Antigen-Presenting Cell–Targeted Vaccine with Toll-like Receptor Stimulation to Induce Immunity to Self-antigens in Cancer Patients

    Michael A. Morse;Robert Chapman;John Powderly;Kimberly Blackwell

  • Immunization with HIV Gag targeted to dendritic cells followed by recombinant New York vaccinia virus induces robust T-cell immunity in nonhuman primates

    Barbara J. Flynn;Kathrin Kastenmüller;Ulrike Wille-Reece;Georgia D. Tomaras

Frequent Co-Authors

Nina Bhardwaj
Nina Bhardwaj Icahn School of Medicine at Mount Sinai
Thomas P. Davis
Thomas P. Davis University of Arizona
Paul K. Wallace
Paul K. Wallace Roswell Park Cancer Institute
Marina Caskey
Marina Caskey Rockefeller University
David A. Reardon
David A. Reardon Harvard University
John H. Sampson
John H. Sampson Duke University
Jan G. J. van de Winkel
Jan G. J. van de Winkel Genmab (United States)
Ralph M. Steinman
Ralph M. Steinman Rockefeller University
Michel C. Nussenzweig
Michel C. Nussenzweig Rockefeller University

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