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Biology and Biochemistry

D-Index
57
Citations
11886
World Ranking
13825
National Ranking
5848

Overview

Duraisamy Kempuraj is a researcher affiliated with the University of Missouri in the United States. Their research spans multiple areas within medicine and neuroscience, with a primary focus on neuroinflammation, neurodegeneration, and related mechanisms. The research also covers traumatic brain injury, neurovascular disturbances, corneal surgery and treatments, as well as the long-term effects of COVID-19.

The main fields of study include:

  • Medicine
  • Neuroscience

Within these fields, their subfields consist of:

  • Neurology
  • Molecular Biology
  • Radiology, Nuclear Medicine and Imaging
  • Immunology
  • Physiology

Kempuraj's research addresses topics such as:

  • Neuroinflammation and Neurodegeneration Mechanisms
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Corneal Surgery and Treatments
  • Long-Term Effects of COVID-19
  • Mast cells and histamine
  • S100 Proteins and Annexins
  • Neurological Disease Mechanisms and Treatments

Some of the recent papers authored by Kempuraj include:

  • COVID-19, Mast Cells, Cytokine Storm, Psychological Stress, and Neuroinflammation (2020) published in The Neuroscientist
  • Neuroprotective effects of flavone luteolin in neuroinflammation and neurotrauma (2020) published in BioFactors

Frequent co-authors collaborating with Kempuraj are:

  • Sudhanshu P. Raikwar
  • Mohammad Ejaz Ahmed
  • Ramasamy Thangavel
  • Asgar Zaheer
  • Govindhasamy Pushpavathi Selvakumar

Kempuraj's work is often published in certain journals, including:

  • Experimental Eye Research
  • International Journal of Molecular Sciences
  • The Neuroscientist
  • Cells
  • Frontiers in Cellular Neuroscience

Best Publications

  • Neuroinflammation Induces Neurodegeneration.

    Kempuraj D;Thangavel R;Natteru Pa;Selvakumar Gp

  • Differential release of mast cell mediators and the pathogenesis of inflammation.

    Theoharis C. Theoharides;Duraisamy Kempuraj;Michael Tagen;Pio Conti

  • Flavonols inhibit proinflammatory mediator release, intracellular calcium ion levels and protein kinase C theta phosphorylation in human mast cells

    Duraisamy Kempuraj;Bhuvaneshwari Madhappan;Spyridon Christodoulou;William Boucher

  • Human mast cells express corticotropin-releasing hormone (CRH) receptors and CRH leads to selective secretion of vascular endothelial growth factor.

    Jing Cao;Nikoletta Papadopoulou;Duraisamy Kempuraj;William S. Boucher

  • IL-33 augments substance P–induced VEGF secretion from human mast cells and is increased in psoriatic skin

    Theoharis C. Theoharides;Bodi Zhang;Duraisamy Kempuraj;Michael Tagen

  • The mast cell in interstitial cystitis: role in pathophysiology and pathogenesis.

    Grannum R. Sant;Duraisamy Kempuraj;Duraisamy Kempuraj;James E. Marchand;James E. Marchand;Theoharis C. Theoharides;Theoharis C. Theoharides

  • Mast cells as targets of corticotropin-releasing factor and related peptides

    Theoharis C. Theoharides;Jill M. Donelan;Nikoletta Papadopoulou;Jing Cao

  • Mast cell involvement in interstitial cystitis: a review of human and experimental evidence

    Theoharis C Theoharides;Duraisamy Kempuraj;Grannum R Sant

  • IL-10, an inflammatory/inhibitory cytokine, but not always.

    Pio Conti;Duraisamy Kempuraj;Kristiana Kandere;Mario Di Gioacchino

  • Brain and Peripheral Atypical Inflammatory Mediators Potentiate Neuroinflammation and Neurodegeneration

    Duraisamy Kempuraj;Duraisamy Kempuraj;Ramasamy Thangavel;Ramasamy Thangavel;Govindhasamy P. Selvakumar;Govindhasamy P. Selvakumar;Smita Zaheer

  • IL-1 induces vesicular secretion of IL-6 without degranulation from human mast cells.

    Kristiana Kandere-Grzybowska;Richard Letourneau;Duraisamy Kempuraj;Jill Donelan

  • COVID-19, Mast Cells, Cytokine Storm, Psychological Stress, and Neuroinflammation.

    Duraisamy Kempuraj;Duraisamy Kempuraj;Govindhasamy Pushpavathi Selvakumar;Govindhasamy Pushpavathi Selvakumar;Mohammad Ejaz Ahmed;Mohammad Ejaz Ahmed;Sudhanshu P. Raikwar;Sudhanshu P. Raikwar

  • Corticotropin-releasing hormone and its structurally related urocortin are synthesized and secreted by human mast cells.

    Duraisamy Kempuraj;Nikoletta G. Papadopoulou;Michael Lytinas;Man Huang

  • Neuroprotective effects of flavone luteolin in neuroinflammation and neurotrauma.

    Duraisamy Kempuraj;Duraisamy Kempuraj;Ramasamy Thangavel;Ramasamy Thangavel;Deepak D. Kempuraj;Mohammad Ejaz Ahmed;Mohammad Ejaz Ahmed

  • Characterization of Mast Cell-Committed Progenitors Present in Human Umbilical Cord Blood

    Duraisamy Kempuraj;Hirohisa Saito;Azusa Kaneko;Kazumi Fukagawa

  • Regulation of IL‐1‐induced selective IL‐6 release from human mast cells and inhibition by quercetin

    Kristiana Kandere-Grzybowska;Duraisamy Kempuraj;Jing Cao;Curtis L Cetrulo

  • Progesterone inhibits mast cell secretion.

    M. Vasiadi;D. Kempuraj;W. Boucher;D. Kalogeromitros

  • IL-10 subfamily members: IL-19, IL-20, IL-22, IL-24 and IL-26.

    P. Conti;D. Kempuraj;S. Frydas;K. Kandere

  • Luteolin inhibits myelin basic protein-induced human mast cell activation and mast cell-dependent stimulation of Jurkat T cells.

    D Kempuraj;M Tagen;B P Iliopoulou;A Clemons

  • Anti-inflammatory actions of flavonoids and structural requirements for new design.

    T C Theoharides;M Alexandrakis;D Kempuraj;M Lytinas

Frequent Co-Authors

Theoharis C. Theoharides
Theoharis C. Theoharides Nova Southeastern University
Pio Conti
Pio Conti University of Chieti-Pescara
Hirohisa Saito
Hirohisa Saito Juntendo University
David K. Meyerholz
David K. Meyerholz University of Iowa
Ruby Pawankar
Ruby Pawankar Nippon Medical School
Shinji Takai
Shinji Takai Kitasato University
Elias Papadopoulos
Elias Papadopoulos Aristotle University of Thessaloniki
Kohichiro Tsuji
Kohichiro Tsuji University of Tokyo
Orian S. Shirihai
Orian S. Shirihai University of California, Los Angeles

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