His primary scientific interests are in Cell biology, Mitochondrion, Mitochondrial fission, Autophagy and mitochondrial fusion. His biological study focuses on Bioenergetics. His studies deal with areas such as Reactive oxygen species, Oxidative phosphorylation, Lipid bilayer fusion and Cell growth as well as Mitochondrion.
His Mitochondrial fission research incorporates themes from MFN2 and FIS1. His Autophagy research includes themes of mTORC1, PI3K/AKT/mTOR pathway, Cell cycle and Stem cell. His mitochondrial fusion research is multidisciplinary, incorporating elements of Cell signaling and Mitophagy.
Orian S. Shirihai focuses on Cell biology, Mitochondrion, Endocrinology, Internal medicine and mitochondrial fusion. His Cell biology research incorporates elements of Autophagy, Mitophagy and Biochemistry. His Autophagy study integrates concerns from other disciplines, such as Lysosome, Programmed cell death and Lipotoxicity.
His biological study spans a wide range of topics, including Oxidative phosphorylation, Brown adipose tissue and Membrane potential. His research in Brown adipose tissue intersects with topics in ATP synthase, Lipid droplet and Thermogenesis. His work on MFN2 and FIS1 as part of his general mitochondrial fusion study is frequently connected to Respiratory function and Fission, thereby bridging the divide between different branches of science.
Orian S. Shirihai spends much of his time researching Cell biology, Mitochondrion, Autophagy, Function and Membrane potential. His research in Cell biology is mostly concerned with Bioenergetics. His Mitochondrion study integrates concerns from other disciplines, such as Cell, mitochondrial fusion, FIS1, Lipid droplet and Mitophagy.
His Autophagy research incorporates themes from Lysosome, Directed differentiation and PLGA. His Function study deals with Respirometry intersecting with Cellular energy, Energy metabolism and Chromatography. The Membrane potential study combines topics in areas such as Preclinical imaging, In vivo and Membrane, Inner mitochondrial membrane.
The scientist’s investigation covers issues in Mitochondrion, Cell biology, Cell, Oxidative phosphorylation and Membrane potential. He is interested in Mitochondrial fission, which is a field of Mitochondrion. His Cell biology research incorporates elements of Cytosol, Apoptosis and Mitochondrial permeability transition pore.
His research integrates issues of Proteome, Beta oxidation, mitochondrial fusion, Motility and Lipid droplet in his study of Cell. Orian S. Shirihai has included themes like Preclinical imaging, Cancer, Cell growth and Membrane, Inner mitochondrial membrane in his Membrane potential study. Insulin is closely connected to Autophagy in his research, which is encompassed under the umbrella topic of Bioenergetics.
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Guidelines for the use and interpretation of assays for monitoring autophagy
Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham.
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin.
Fission and selective fusion govern mitochondrial segregation and elimination by autophagy
Gilad Twig;Alvaro Elorza;Anthony J A Molina;Anthony J A Molina;Hibo Mohamed.
The EMBO Journal (2008)
Pancreatic cancers require autophagy for tumor growth
Shenghong Yang;Xiaoxu Wang;Gianmarco Contino;Marc Liesa.
Genes & Development (2011)
Telomere dysfunction induces metabolic and mitochondrial compromise
Ergiin Sahin;Simona Colla;Marc Liesa;Javid Moslehi.
The Histone Deacetylase Sirt6 Regulates Glucose Homeostasis via Hif1α
Lei Zhong;Agustina D'Urso;Debra Toiber;Carlos Sebastian.
Mitochondrial Dynamics in the Regulation of Nutrient Utilization and Energy Expenditure
Marc Liesa;Orian S. Shirihai;Orian S. Shirihai.
Cell Metabolism (2013)
Mitochondrial fusion, fission and autophagy as a quality control axis: The bioenergetic view
Gilad Twig;Brigham Hyde;Brigham Hyde;Orian S. Shirihai;Orian S. Shirihai.
Biochimica et Biophysica Acta (2008)
The Interplay Between Mitochondrial Dynamics and Mitophagy
Gilad Twig;Orian S. Shirihai.
Antioxidants & Redox Signaling (2011)
Altered Mitochondrial Dynamics Contributes to Endothelial Dysfunction in Diabetes Mellitus
Sherene M. Shenouda;Michael E. Widlansky;Kai Chen;Guoquan Xu.
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