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Petter Höglund

Petter Höglund

D-Index & Metrics

Immunology

D-Index
47
Citations
9690
World Ranking
4500
National Ranking
103

Overview

Petter Höglund is affiliated with the Karolinska Institute in Sweden and has a substantial body of research in immunology, medicine, and related subfields. Their scientific work primarily focuses on immune cell function and interaction, blood disorders and treatments, immunodeficiency and autoimmune disorders, and T-cell and B-cell immunology. They have also contributed to research on CAR-T cell therapy, blood groups and transfusion, as well as IL-33, ST2, and ILC pathways.

Their recent publications include diverse topics within immunology and oncology. Notable papers are:

  • Platelet-Mediated Protection of Cancer Cells From Immune Surveillance - Possible Implications for Cancer Immunotherapy (2021) published in Frontiers in Immunology
  • The European Guidelines on Diagnosis and Management of Neutropenia in Adults and Children: A Consensus Between the European Hematology Association and the EuNet-INNOCHRON COST Action (2023) published in HemaSphere
  • Adaptive single-KIR+NKG2C+ NK cells expanded from select superdonors show potent missing-self reactivity and efficiently control HLA-mismatched acute myeloid leukemia (2022) published in Journal for ImmunoTherapy of Cancer
  • Frequent platelet donation is associated with lymphopenia and risk of infections: A nationwide cohort study (2020) published in Transfusion
  • SHP-1 localization to the activating immune synapse promotes NK cell tolerance in MHC class I deficiency (2023) published in Science Signaling

Petter Höglund's frequently collaborating coauthors include Stephan Meinke, Hans-Gustaf Ljunggren, Roland Jonsson, Laurent Schmied, and Nadir Kadri. These collaborations have contributed to a significant portion of their scientific output.

Their research is frequently published in several specialized journals with multiple contributions noted in the following venues:

  • Scandinavian Journal of Immunology (27 publications)
  • HemaSphere (4 publications)
  • Transfusion (4 publications)
  • Frontiers in Immunology (2 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (2 publications)

Petter Höglund's main fields of study include Immunology and Microbiology with 57 publications and Medicine with 50 publications. Within these fields, they have focused on subfields such as Immunology, Genetics, Oncology, Hematology, and Molecular Biology.

Their research topics show a broad engagement with areas including:

  • Immune Cell Function and Interaction
  • Blood disorders and treatments
  • Immunodeficiency and Autoimmune Disorders
  • T-cell and B-cell Immunology
  • CAR-T cell therapy research
  • Blood groups and transfusion
  • IL-33, ST2, and ILC Pathways

Best Publications

  • Empty MHC class I molecules come out in the cold

    H G Ljunggren;N J Stam;C Ohlén;J J Neefjes

  • Initiation of Autoimmune Diabetes by Developmentally Regulated Presentation of Islet Cell Antigens in the Pancreatic Lymph Nodes

    Petter Höglund;Justine Mintern;Caroline Waltzinger;William Heath

  • Cytotoxic T Lymphocyte–associated Antigen 4 (CTLA-4) Regulates the Unfolding of Autoimmune Diabetes

    Fred Lühder;Petter Höglund;James P. Allison;Christophe Benoist

  • NCRs and DNAM-1 mediate NK cell recognition and lysis of human and mouse melanoma cell lines in vitro and in vivo

    Tadepally Lakshmikanth;Shannon Burke;Talib Hassan Ali;Silvia Kimpfler

  • Recognition of beta 2-microglobulin-negative (beta 2m-) T-cell blasts by natural killer cells from normal but not from beta 2m- mice: nonresponsiveness controlled by beta 2m- bone marrow in chimeric mice

    Petter Hoglund;Claes Ohlen;Ennio Carbone;Lars Franksson

  • NK cell education: not an on-off switch but a tunable rheostat

    Petter Brodin;Klas Kärre;Petter Höglund

  • The strength of inhibitory input during education quantitatively tunes the functional responsiveness of individual natural killer cells

    Petter Brodin;Tadepally Lakshmikanth;Sofia Johansson;Klas Kärre

  • Current perspectives of natural killer cell education by MHC class I molecules

    Petter Höglund;Petter Brodin

  • Prevention of allogeneic bone marrow graft rejection by H-2 transgene in donor mice

    Claes Öhlén;Gunilla Kling;Petter Höglund;Mona Hansson

  • Allorecognition by NK cells: nonself or no self?

    Lorenzo Moretta;Ermanno Ciccone;Alessandro Moretta;Petter Höglund

  • Host MHC class I gene control of NK-cell specificity in the mouse.

    Petter Hoglund;Jonas Sundback;Mats Y. Olsson-Alheim;Maria Johansson

  • Natural killer cell education in mice with single or multiple major histocompatibility complex class I molecules

    Sofia Johansson;Maria Johansson;Eleftheria Rosmaraki;Gustaf Vahlne

  • Natural Killer Cell Tolerance in Mice with Mosaic Expression of Major Histocompatibility Complex Class I Transgene

    Maria H. Johansson;Charles Bieberich;Gilbert Jay;Klas Kärre

  • A Role for cis Interaction between the Inhibitory Ly49A Receptor and MHC Class I for Natural Killer Cell Education

    Anick Chalifour;Léonardo Scarpellino;Jonathan Back;Petter Brodin

  • NK cells: elusive players in autoimmunity.

    Sofia Johansson;Louise Berg;Håkan Hall;Petter Höglund

  • Natural resistance against lymphoma grafts conveyed by H-2Dd transgene to C57BL mice.

    P Höglund;H G Ljunggren;C Ohlén;L Ahrlund-Richter

  • The CD8+ T cell repertoire in beta 2-microglobulin-deficient mice is biased towards reactivity against self-major histocompatibility class I.

    R Glas;C Ohlén;P Höglund;K Kärre

  • Interferon gamma induces lung colonization by intravenously inoculated B16 melanoma cells in parallel with enhanced expression of class I major histocompatibility complex antigens

    K Taniguchi;M Petersson;P Höglund;R Kiessling

  • Acquisition of External Major Histocompatibility Complex Class I Molecules by Natural Killer Cells Expressing Inhibitory Ly49 Receptors

    Anna Sjöström;Mikael Eriksson;Cristina Cerboni;Maria H. Johansson

  • Natural killer cells in human autoimmunity.

    Malin Flodström-Tullberg;Yenan T Bryceson;Fu-Dong Shi;Petter Höglund

Frequent Co-Authors

Klas Kärre
Klas Kärre Karolinska Institute
Hans-Gustaf Ljunggren
Hans-Gustaf Ljunggren Karolinska Institute
Petter Brodin
Petter Brodin Karolinska Institute
Håkan Hall
Håkan Hall Karolinska Institute
George Klein
George Klein Karolinska Institute
Eric Vivier
Eric Vivier Aix-Marseille University
Elena Tomasello
Elena Tomasello Aix-Marseille University
Daniel M. Davis
Daniel M. Davis University of Manchester
Gilbert Jay
Gilbert Jay American Red Cross
Anders Österborg
Anders Österborg Karolinska Institute

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