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Biology and Biochemistry

D-Index
67
Citations
16826
World Ranking
8182
National Ranking
3699

Overview

Daniel W. McVicar is affiliated with the National Institutes of Health in the United States. Their research spans the fields of Medicine, Biochemistry, Genetics and Molecular Biology, and Immunology and Microbiology. Within these broader disciplines, their work focuses particularly on Immunology, Molecular Biology, Oncology, Cancer Research, and Pharmacology.

Their research topics include:

  • Immune cells in cancer
  • Cancer Immunotherapy and Biomarkers
  • Cancer, Hypoxia, and Metabolism
  • Inflammatory mediators and NSAID effects
  • Immunotherapy and Immune Responses
  • Cancer, Stress, Anesthesia, and Immune Response
  • Peroxisome Proliferator-Activated Receptors

McVicar has published extensively in venues such as bioRxiv (Cold Spring Harbor Laboratory), The Journal of Immunology, Cancer Research, Nature Communications, and Frontiers in Oncology.

Frequent co-authors include David A. Wink, Erika M. Palmieri, Lisa A. Ridnour, Stephen Lockett, and Sharon A. Glynn.

Selected recent papers authored or co-authored by McVicar include:

  • "Nitric oxide orchestrates metabolic rewiring in M1 macrophages by targeting aconitase 2 and pyruvate dehydrogenase," 2020, Nature Communications
  • "Nitric Oxide in Macrophage Immunometabolism: Hiding in Plain Sight," 2020, Metabolites
  • "Itaconic acid underpins hepatocyte lipid metabolism in non-alcoholic fatty liver disease in male mice," 2023, Nature Metabolism
  • "Mycobacterium tuberculosis Induces Irg1 in Murine Macrophages by a Pathway Involving Both TLR-2 and STING/IFNAR Signaling and Requiring Bacterial Phagocytosis," 2022, Frontiers in Cellular and Infection Microbiology
  • "Pyruvate dehydrogenase operates as an intramolecular nitroxyl generator during macrophage metabolic reprogramming," 2023, Nature Communications

Best Publications

  • Innate partnership of HLA-B and KIR3DL1 subtypes against HIV-1

    Maureen P. Martin;Ying Qi;Xiaojiang Gao;Eriko Yamada

  • Interaction of IL-2R beta and gamma c chains with Jak1 and Jak3 : implications for XSCID and XCID

    Sarah M. Russell;James A. Johnston;Masayuki Noguchi;Masaru Kawamura

  • Alterations in signal transduction molecules in T lymphocytes from tumor-bearing mice.

    Hiromoto Mizoguchi;John J. O'Shea;Dan L. Longo;Cynthia M. Loeffler

  • Phosphorylation and activation of the Jak-3 Janus kinase in response to interleukin-2

    James A. Johnston;Masaru Kawamura;Robert A. Kirken;Yi Qing Chen

  • NAFLD causes selective CD4 + T lymphocyte loss and promotes hepatocarcinogenesis

    Chi Ma;Aparna H. Kesarwala;Tobias Eggert;José Medina-Echeverz

  • TREM and TREM-like Receptors in Inflammation and Disease

    Jill W Ford;Daniel W McVicar

  • Requirement for Tec Kinases Rlk and Itk in T Cell Receptor Signaling and Immunity

    Edward M. Schaeffer;Jayanta Debnath;George Yap;Daniel McVicar

  • Interleukin 12 (IL-12) induces tyrosine phosphorylation of JAK2 and TYK2: differential use of Janus family tyrosine kinases by IL-2 and IL-12.

    Chris M. Bacon;Daniel W. McVicar;John R. Ortaldo;Robert C. Rees

  • Molecular cloning of L-JAK, a Janus family protein-tyrosine kinase expressed in natural killer cells and activated leukocytes

    M Kawamura;D W McVicar;J A Johnston;T B Blake

  • Tumour-elicited neutrophils engage mitochondrial metabolism to circumvent nutrient limitations and maintain immune suppression

    Christopher M. Rice;Luke C. Davies;Jeff J. Subleski;Nunziata Maio

  • Pathogen-specific loss of host resistance in mice lacking the IFN-γ-inducible gene IGTP

    Gregory A. Taylor;Carmen M. Collazo;George S. Yap;Khuong Nguyen

  • The Killer Immunoglobulin-Like Receptor Gene Cluster: Tuning the Genome for Defense*

    Arman A. Bashirova;Maureen P. Martin;Daniel W. McVicar;Mary Carrington

  • HLA-C cell surface expression and control of HIV/AIDS correlate with a variant upstream of HLA-C

    Rasmi Thomas;Richard Apps;Ying Qi;Xiaojiang Gao

  • Nitric oxide orchestrates metabolic rewiring in M1 macrophages by targeting aconitase 2 and pyruvate dehydrogenase.

    Erika M. Palmieri;Marieli Gonzalez-Cotto;Walter A. Baseler;Luke C. Davies

  • Lentiviral hematopoietic stem cell gene therapy for X-linked severe combined immunodeficiency

    Suk See De Ravin;Xiaolin Wu;Susan Moir;Lela Kardava

  • Pharmacologic or Genetic Targeting of Glutamine Synthetase Skews Macrophages toward an M1-like Phenotype and Inhibits Tumor Metastasis

    Erika M. Palmieri;Alessio Menga;Rosa Martín-Pérez;Annamaria Quinto

  • Cutting Edge: Allele-specific and peptide-dependent interactions between KIR3DL1 and HLA-A and HLA-B.

    Hathairat Thananchai;Geraldine Gillespie;Maureen P. Martin;Arman Bashirova

  • DAP12-mediated signal transduction in natural killer cells. A dominant role for the Syk protein-tyrosine kinase.

    Daniel W. McVicar;Lynn S. Taylor;Pierre Gosselin;Jami Willette-Brown

  • Myeloid specific human CD33 is an inhibitory receptor with differential ITIM function in recruiting the phosphatases SHP-1 and SHP-2

    Sujatha P. Paul;Lynn S. Taylor;Eryn K. Stansbury;Daniel W. McVicar

  • Activation of human peripheral blood T lymphocytes by pharmacological induction of protein-tyrosine phosphorylation

    John J. O'Shea;Daniel W. McVicar;Trevor L. Bailey;Chris Burns

Frequent Co-Authors

John R. Ortaldo
John R. Ortaldo National Institutes of Health
Stephen K. Anderson
Stephen K. Anderson National Institutes of Health
David A. Wink
David A. Wink National Institutes of Health
John J. O'Shea
John J. O'Shea National Institutes of Health
Mary Carrington
Mary Carrington Ragon Institute of MGH, MIT and Harvard
Jamie Rossjohn
Jamie Rossjohn Monash University
Dan L. Longo
Dan L. Longo Harvard University
Pamela L. Schwartzberg
Pamela L. Schwartzberg National Institutes of Health
Maureen P. Martin
Maureen P. Martin National Institutes of Health

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