D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Microbiology D-index 53 Citations 10,375 119 World Ranking 2964 National Ranking 1195

Research.com Recognitions

Awards & Achievements

2020 - Distinguished Fellows of the American Association of Immunologists (AAI)

2006 - AAI Distinguished Service Award, American Association of Immunologists For dedicated leadership as the Chair of the AAI Program Committee, 2003-2006

2001 - AAI-BD Biosciences Investigator Award, American Association of Immunologists

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Immune system
  • Cytokine

His scientific interests lie mostly in Cell biology, T-cell receptor, Tyrosine kinase, T cell and Signal transduction. His Cell biology research is multidisciplinary, incorporating perspectives in Interleukin 2 and B cell. His T-cell receptor research incorporates elements of Thymocyte, Cytokine, Biochemistry, Antigen and Molecular biology.

His Tyrosine kinase study combines topics from a wide range of disciplines, such as Tyrosine, Cancer research and Kinase, Proto-oncogene tyrosine-protein kinase Src, Kinase activity. His T cell research includes elements of Cytotoxic T cell, T lymphocyte and Transcription factor. His research in Signal transduction intersects with topics in Receptor and Immunology.

His most cited work include:

  • Defects in B Lymphocyte Maturation and T Lymphocyte Activation in Mice Lacking Jak3 (511 citations)
  • T-Cell Signaling Regulated by the Tec Family Kinase, Itk (460 citations)
  • A TCR Binds to Antagonist Ligands with Lower Affinities and Faster Dissociation Rates Than to Agonists (406 citations)

What are the main themes of his work throughout his whole career to date?

Cell biology, T cell, T-cell receptor, Cytotoxic T cell and Immunology are his primary areas of study. His Cell biology research includes themes of CD28 and Receptor. The study incorporates disciplines such as Cancer research, T lymphocyte, Cytokine, Cellular differentiation and CD8 in addition to T cell.

His work carried out in the field of T-cell receptor brings together such families of science as Transgene, Molecular biology and Major histocompatibility complex, Antigen. His Tyrosine kinase research is multidisciplinary, relying on both Tyrosine and Proto-oncogene tyrosine-protein kinase Src, Phosphorylation, Kinase activity. His work on Tyrosine phosphorylation as part of general Signal transduction study is frequently connected to Protein kinase domain, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them.

He most often published in these fields:

  • Cell biology (64.08%)
  • T cell (47.18%)
  • T-cell receptor (41.55%)

What were the highlights of his more recent work (between 2013-2021)?

  • T cell (47.18%)
  • Cell biology (64.08%)
  • CD8 (23.24%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are T cell, Cell biology, CD8, Cytotoxic T cell and T-cell receptor. Leslie J. Berg interconnects IRF4, Virus, Cancer research and Cytokine in the investigation of issues within T cell. His research links Receptor with Cell biology.

His work carried out in the field of CD8 brings together such families of science as Flow cytometry and Major histocompatibility complex. The Cytotoxic T cell study combines topics in areas such as Innate lymphoid cell and Immunology. His work deals with themes such as Gene expression, Cellular differentiation, Tyrosine kinase, Transcription factor and Memory T cell, which intersect with T-cell receptor.

Between 2013 and 2021, his most popular works were:

  • Suppression of systemic autoimmunity by the innate immune adaptor STING (93 citations)
  • TCF1 Is Required for the T Follicular Helper Cell Response to Viral Infection (87 citations)
  • Graded Levels of IRF4 Regulate CD8+ T Cell Differentiation and Expansion, but Not Attrition, in Response to Acute Virus Infection (68 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Immune system
  • Cytokine

Leslie J. Berg spends much of his time researching Cell biology, Immunology, T-cell receptor, T cell and Cytotoxic T cell. His primary area of study in Cell biology is in the field of Signal transduction. In general Immunology, his work in Stimulator of interferon genes, Systemic inflammation, Innate immune system and Proinflammatory cytokine is often linked to Sting linking many areas of study.

Leslie J. Berg has included themes like Tyrosine kinase, Gene expression, Kinase and Cellular differentiation in his T-cell receptor study. As part of the same scientific family, Leslie J. Berg usually focuses on T cell, concentrating on Cancer research and intersecting with IL-2 receptor and Eomesodermin. His Cytotoxic T cell research includes elements of Influenza A virus and Effector.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Defects in B Lymphocyte Maturation and T Lymphocyte Activation in Mice Lacking Jak3

Daniel C. Thomis;Christine B. Gurniak;Elizabeth Tivol;Arlene H. Sharpe.
Science (1995)

609 Citations

A TCR Binds to Antagonist Ligands with Lower Affinities and Faster Dissociation Rates Than to Agonists

Daniel S. Lyons;Stephanie A. Lieberman;Johannes Hampl;J. Jay Boniface.
Immunity (1996)

519 Citations

T-Cell Signaling Regulated by the Tec Family Kinase, Itk

Amy H. Andreotti;Pamela L. Schwartzberg;Raji E. Joseph;Leslie J. Berg.
Cold Spring Harbor Perspectives in Biology (2010)

515 Citations

Antigen/MHC-specific T cells are preferentially exported from the thymus in the presence of their MHC ligand.

Leslie J. Berg;Ann M. Pullen;Barbara Fazekas de St. Groth;Diane Mathis;Diane Mathis.
Cell (1989)

480 Citations

Regulation of the polarization of T cells toward antigen-presenting cells by Ras-related GTPase CDC42

Lisa Stowers;Deborah Yelon;Leslie J. Berg;John Chant.
Proceedings of the National Academy of Sciences of the United States of America (1995)

463 Citations

T Cell Receptor–initiated Calcium Release Is Uncoupled from Capacitative Calcium Entry in Itk-deficient T Cells

Karen-Qianye Liu;Stephen C. Bunnell;Christine B. Gurniak;Leslie J. Berg.
Journal of Experimental Medicine (1998)

415 Citations

TEC FAMILY KINASES IN T LYMPHOCYTE DEVELOPMENT AND FUNCTION

Leslie J. Berg;Lisa D. Finkelstein;Julie Ann Lucas;Pamela L. Schwartzberg.
Annual Review of Immunology (2005)

397 Citations

Biochemical interactions integrating Itk with the T cell receptor-initiated signaling cascade.

Stephen C. Bunnell;Maximilian Diehn;Michael B. Yaffe;Paul R. Findell.
Journal of Biological Chemistry (2000)

330 Citations

Regulatory intramolecular association in a tyrosine kinase of the Tec family.

Amy Hamilton Andreotti;Stephen C. Bunnell;Sibo Feng;Leslie J. Berg.
Nature (1997)

329 Citations

p56Lck and p59Fyn regulate CD28 binding to phosphatidylinositol 3-kinase, growth factor receptor-bound protein GRB-2, and T cell-specific protein-tyrosine kinase ITK: implications for T-cell costimulation

Monika Raab;Yun-Cai Cai;Stephen C. Bunnell;Stephanie D. Heyeck.
Proceedings of the National Academy of Sciences of the United States of America (1995)

234 Citations

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