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Immunology

D-Index
57
Citations
12100
World Ranking
3623
National Ranking
1673

Research.com Recognitions

  • 2020 - Distinguished Fellows of the American Association of Immunologists (AAI)
  • 2006 - AAI Distinguished Service Award, American Association of Immunologists For dedicated leadership as the Chair of the AAI Program Committee, 2003-2006
  • 2001 - AAI-BD Biosciences Investigator Award, American Association of Immunologists

Overview

Leslie J. Berg is affiliated with the University of Colorado Anschutz Medical Campus in the United States. Their research primarily spans the fields of Medicine and Immunology and Microbiology, with a focus on Immunology, Oncology, Cellular and Molecular Neuroscience, Epidemiology, and Pathology and Forensic Medicine as significant subfields of study.

Their work extensively addresses several main topics including Immune Cell Function and Interaction, T-cell and B-cell Immunology, CAR-T cell therapy research, Nuclear Receptors and Signaling, Cytokine Signaling Pathways and Interactions, Cytomegalovirus and herpesvirus research, and Viral-associated cancers and disorders.

Recent papers authored by Leslie J. Berg include:

  • Activation of the Tec Kinase ITK Controls Graded IRF4 Expression in Response to Variations in TCR Signal Strength, 2020, The Journal of Immunology
  • VAV1 as a putative therapeutic target in autoimmune and chronic inflammatory diseases, 2024, Trends in Immunology
  • CD8+ T Cells Require ITK-Mediated TCR Signaling for Migration to the Intestine, 2020, ImmunoHorizons
  • Optimized Detection of Acute MHV68 Infection With a Reporter System Identifies Large Peritoneal Macrophages as a Dominant Target of Primary Infection, 2021, Frontiers in Microbiology
  • Interplay between IL-10, IFN-γ, IL-17A and PD-1 Expressing EBNA1-Specific CD4+ and CD8+ T Cell Responses in the Etiologic Pathway to Endemic Burkitt Lymphoma, 2021, Cancers

Frequent co-authors collaborating with Leslie J. Berg include Loni Perrenoud, Andrea Reboldi, Josh Hunkins, James Conley, and J. David Beckham.

Publications by Leslie J. Berg are frequently found in several venues, primarily:

  • The Journal of Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Investigative Dermatology
  • Trends in Immunology
  • ImmunoHorizons

Over the course of their career, Leslie J. Berg has received several awards including the Distinguished Fellows of the American Association of Immunologists (AAI) in 2020, the AAI Distinguished Service Award in 2006 for leadership as Chair of the AAI Program Committee from 2003 to 2006, and the AAI-BD Biosciences Investigator Award in 2001.

Best Publications

  • Defects in B Lymphocyte Maturation and T Lymphocyte Activation in Mice Lacking Jak3

    Daniel C. Thomis;Christine B. Gurniak;Elizabeth Tivol;Arlene H. Sharpe

  • T-Cell Signaling Regulated by the Tec Family Kinase, Itk

    Amy H. Andreotti;Pamela L. Schwartzberg;Raji E. Joseph;Leslie J. Berg

  • A TCR Binds to Antagonist Ligands with Lower Affinities and Faster Dissociation Rates Than to Agonists

    Daniel S. Lyons;Stephanie A. Lieberman;Johannes Hampl;J. Jay Boniface

  • Antigen/MHC-specific T cells are preferentially exported from the thymus in the presence of their MHC ligand.

    Leslie J. Berg;Ann M. Pullen;Barbara Fazekas de St. Groth;Diane Mathis;Diane Mathis

  • Regulation of the polarization of T cells toward antigen-presenting cells by Ras-related GTPase CDC42

    Lisa Stowers;Deborah Yelon;Leslie J. Berg;John Chant

  • TEC FAMILY KINASES IN T LYMPHOCYTE DEVELOPMENT AND FUNCTION

    Leslie J. Berg;Lisa D. Finkelstein;Julie Ann Lucas;Pamela L. Schwartzberg

  • T Cell Receptor–initiated Calcium Release Is Uncoupled from Capacitative Calcium Entry in Itk-deficient T Cells

    Karen-Qianye Liu;Stephen C. Bunnell;Christine B. Gurniak;Leslie J. Berg

  • Biochemical interactions integrating Itk with the T cell receptor-initiated signaling cascade.

    Stephen C. Bunnell;Maximilian Diehn;Michael B. Yaffe;Paul R. Findell

  • Regulatory intramolecular association in a tyrosine kinase of the Tec family.

    Amy Hamilton Andreotti;Stephen C. Bunnell;Sibo Feng;Leslie J. Berg

  • Asymmetric Proteasome Segregation as a Mechanism for Unequal Partitioning of the Transcription Factor T-bet during T Lymphocyte Division

    John T. Chang;Maria L. Ciocca;Ichiko Kinjyo;Vikram R. Palanivel

  • p56Lck and p59Fyn regulate CD28 binding to phosphatidylinositol 3-kinase, growth factor receptor-bound protein GRB-2, and T cell-specific protein-tyrosine kinase ITK: implications for T-cell costimulation

    Monika Raab;Yun-Cai Cai;Stephen C. Bunnell;Stephanie D. Heyeck

  • Intrathymic programming of effector fates in three molecularly distinct γδ T cell subtypes

    Kavitha Narayan;Katelyn E. Sylvia;Nidhi Malhotra;Catherine C. Yin

  • The Tec Family Tyrosine Kinases Itk and Rlk Regulate the Development of Conventional CD8+ T Cells

    Luana O. Atherly;Julie Ann Lucas;Martin Felices;Catherine C. Yin

  • Identification of Itk/Tsk Src homology 3 domain ligands.

    Stephen C. Bunnell;Pamela A. Henry;Rikki Kolluri;Tomas Kirchhausen

  • Lck Phosphorylates the Activation Loop Tyrosine of the Itk Kinase Domain and Activates Itk Kinase Activity

    Stephanie D. Heyeck;Heather M. Wilcox;Stephen C. Bunnell;Leslie J. Berg

  • Signaling through Itk promotes T helper 2 differentiation via negative regulation of T-bet

    Andrew Todd Miller;Heather M. Wilcox;Zhongbin Lai;Leslie J. Berg

  • A Network of High-Mobility Group Box Transcription Factors Programs Innate interleukin-17 Production

    Nidhi Malhotra;Kavitha Narayan;Ok Hyun Cho;Katelyn E. Sylvia

  • Developmental regulation of a murine T-cell-specific tyrosine kinase gene, Tsk.

    Stephanie D. Heyeck;Leslie J. Berg

  • TCF1 Is Required for the T Follicular Helper Cell Response to Viral Infection

    Tuoqi Wu;Hyun Mu Shin;E. Ashley Moseman;Yun Ji

  • Signalling through TEC kinases regulates conventional versus innate CD8+ T-cell development

    Leslie J. Berg

  • Interleukin 7 Receptor Control of T Cell Receptor γ Gene Rearrangement: Role of Receptor-associated Chains and Locus Accessibility

    Scott K. Durum;Serge Candèias;Hiroshi Nakajima;Warren J. Leonard

  • Janus-kinase-3-dependent signals induce chromatin remodeling at the Ifng locus during T helper 1 cell differentiation.

    Min Shi;Tsung H. Lin;Kenneth C. Appell;Leslie J. Berg

Frequent Co-Authors

Mark M. Davis
Mark M. Davis Stanford University
Raymond M. Welsh
Raymond M. Welsh University of Massachusetts Chan Medical School
Michael A. Brehm
Michael A. Brehm University of Massachusetts Chan Medical School
Pamela L. Schwartzberg
Pamela L. Schwartzberg National Institutes of Health
Deborah Yelon
Deborah Yelon University of California, San Diego
Susan L. Swain
Susan L. Swain University of Massachusetts Chan Medical School
Craig J. Thomas
Craig J. Thomas National Institutes of Health
Katherine A. Fitzgerald
Katherine A. Fitzgerald University of Massachusetts Chan Medical School
Anjana Rao
Anjana Rao La Jolla Institute For Allergy & Immunology
Diane Mathis
Diane Mathis Harvard University

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