D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 56 Citations 15,090 172 World Ranking 2709 National Ranking 1287

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Immune system
  • Cancer

Michael A. Brehm mostly deals with Immunology, Immune system, CD8, Virology and T cell. Michael A. Brehm specializes in Immunology, namely Immunity. His research integrates issues of Cancer research and Stem cell in his study of Immune system.

Michael A. Brehm combines subjects such as Cytotoxic T cell and CD40 with his study of CD8. His Virology research incorporates elements of Heterologous and Immune tolerance. His studies in T cell integrate themes in fields like Chromatin, Cell culture and Molecular biology.

His most cited work include:

  • Repair of Infarcted Myocardium by Autologous Intracoronary Mononuclear Bone Marrow Cell Transplantation in Humans (2032 citations)
  • Humanized mice for immune system investigation: progress, promise and challenges. (640 citations)
  • Regeneration of Human Infarcted Heart Muscle by Intracoronary Autologous Bone Marrow Cell Transplantation in Chronic Coronary Artery Disease: The IACT Study (366 citations)

What are the main themes of his work throughout his whole career to date?

Michael A. Brehm mainly focuses on Immunology, Immune system, T cell, Transplantation and Cytotoxic T cell. His biological study spans a wide range of topics, including Nod and Virology. His Immune system research is multidisciplinary, incorporating perspectives in Cancer research and Stem cell.

Michael A. Brehm studied T cell and Major histocompatibility complex that intersect with Graft-versus-host disease. His Transplantation study incorporates themes from Bone marrow and Myocardial infarction, Cardiology. His Cytotoxic T cell study combines topics from a wide range of disciplines, such as Apoptosis and T-cell receptor.

He most often published in these fields:

  • Immunology (51.40%)
  • Immune system (32.96%)
  • T cell (22.35%)

What were the highlights of his more recent work (between 2018-2021)?

  • Immune system (32.96%)
  • Cancer research (15.08%)
  • Humanized mouse (12.85%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Immune system, Cancer research, Humanized mouse, Cytokine and Immunology. The various areas that he examines in his Immune system study include Nod and Monoclonal antibody. His Cancer research study combines topics in areas such as Haematopoiesis, Stem cell and Immune checkpoint inhibitors.

His Humanized mouse study integrates concerns from other disciplines, such as Regenerative medicine, Antibody-dependent cell-mediated cytotoxicity, Transplantation and Immunotherapy. His Immunology study frequently involves adjacent topics like Receptor. His T cell study incorporates themes from MHC class I, CD8, Blood cell, Peripheral blood mononuclear cell and Graft-versus-host disease.

Between 2018 and 2021, his most popular works were:

  • Humanized immune system mouse models: progress, challenges and opportunities. (46 citations)
  • Lack of acute xenogeneic graft- versus-host disease, but retention of T-cell function following engraftment of human peripheral blood mononuclear cells in NSG mice deficient in MHC class I and II expression. (41 citations)
  • Humanized mouse models of immunological diseases and precision medicine (31 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Immune system
  • Cancer

His main research concerns Immune system, Humanized mouse, Cancer research, Antibody and Immunology. The concepts of his Immune system study are interwoven with issues in Flow cytometry, In vitro, Stem cell and Human type. His research in Humanized mouse intersects with topics in Precision medicine, Regenerative medicine and Computational biology.

His Cancer research research includes elements of Haematopoiesis, Nod, T cell subset, Immunity and Human cancer. His work deals with themes such as MHC class I, CD8, Major histocompatibility complex, Peripheral blood mononuclear cell and Graft-versus-host disease, which intersect with Antibody. Immunology is often connected to Ex vivo in his work.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Repair of Infarcted Myocardium by Autologous Intracoronary Mononuclear Bone Marrow Cell Transplantation in Humans

Bodo E. Strauer;Michael Brehm;Tobias Zeus;Matthias Köstering.
Circulation (2002)

3300 Citations

Humanized mice for immune system investigation: progress, promise and challenges.

Leonard D. Shultz;Michael A. Brehm;J. Victor Garcia-Martinez;Dale L. Greiner.
Nature Reviews Immunology (2012)

1117 Citations

Regeneration of Human Infarcted Heart Muscle by Intracoronary Autologous Bone Marrow Cell Transplantation in Chronic Coronary Artery Disease: The IACT Study

Bodo E. Strauer;Michael Brehm;Tobias Zeus;Thomas Bartsch.
Journal of the American College of Cardiology (2005)

570 Citations

Humanized Mouse Models of Clinical Disease.

Nicole C. Walsh;Laurie L. Kenney;Sonal Jangalwe;Ken-Edwin Aryee.
Annual Review of Pathology-mechanisms of Disease (2017)

469 Citations

Human peripheral blood leucocyte non-obese diabetic-severe combined immunodeficiency interleukin-2 receptor gamma chain gene mouse model of xenogeneic graft-versus-host-like disease and the role of host major histocompatibility complex.

M A King;L Covassin;M A Brehm;W Racki.
Clinical and Experimental Immunology (2009)

396 Citations

The BALANCE Study: clinical benefit and long-term outcome after intracoronary autologous bone marrow cell transplantation in patients with acute myocardial infarction.

Muhammad Yousef;Christiana Mira Schannwell;Mathias Köstering;Tobias Zeus.
Journal of the American College of Cardiology (2009)

332 Citations

An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia.

Birgit Knoechel;Justine E Roderick;Kaylyn E Williamson;Jiang Zhu.
Nature Genetics (2014)

330 Citations

Parameters for establishing humanized mouse models to study human immunity: analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rgamma(null) mutation.

Michael A. Brehm;Amy Cuthbert;Chaoxing Yang;David M. Miller.
Clinical Immunology (2010)

316 Citations

Repair of coronary arterioles after treatment with perindopril in hypertensive heart disease.

Bodo Schwartzkopff;Michael Brehm;Markus Mundhenke;Bodo E. Strauer.
Hypertension (2000)

315 Citations

Memory CD8+ T cells in heterologous antiviral immunity and immunopathology in the lung.

Hong D. Chen;Armando E. Fraire;Isabelle Joris;Michael A. Brehm.
Nature Immunology (2001)

305 Citations

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