World's Best Scientists 2026 revealed!

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Immunology

D-Index
127
Citations
79421
World Ranking
259
National Ranking
168

Medicine

D-Index
127
Citations
83080
World Ranking
2781
National Ranking
1550

Overview

Stephan R. Targan is affiliated with Cedars-Sinai Medical Center in the United States. Their research primarily focuses on Medicine and Biochemistry, Genetics and Molecular Biology, with extensive contributions in Genetics, Epidemiology, Immunology, Surgery, and Infectious Diseases.

The core topics of their work include:

  • Inflammatory Bowel Disease
  • Microscopic Colitis
  • Immunodeficiency and Autoimmune Disorders
  • Cancer Cells and Metastasis
  • IL-33, ST2, and ILC Pathways
  • Digestive system and related health
  • Hidradenitis Suppurativa and Treatments

Targan has authored numerous research papers, with recent publications including:

  • "Five-Year Efficacy and Safety of Ustekinumab Treatment in Crohn's Disease: The IM-UNITI Trial", 2021, Clinical Gastroenterology and Hepatology
  • "Altered Intestinal ACE2 Levels Are Associated With Inflammation, Severe Disease, and Response to Anti-Cytokine Therapy in Inflammatory Bowel Disease", 2020, Gastroenterology
  • "Ustekinumab is effective and safe for ulcerative colitis through 2 years of maintenance therapy", 2020, Alimentary Pharmacology & Therapeutics
  • "Higher Intra-Abdominal Visceral Adipose Tissue Mass Is Associated With Lower Rates of Clinical and Endoscopic Remission in Patients With Inflammatory Bowel Diseases Initiating Biologic Therapy: Results of the Constellation Study", 2023, Gastroenterology
  • "Effect and Mechanism of TL1A Expression on Epithelial-Mesenchymal Transition during Chronic Colitis-Related Intestinal Fibrosis", 2021, Mediators of Inflammation

Their frequent collaborators include Dermot McGovern, Gil Melmed, Shervin Rabizadeh, Dalin Li, and Talin Haritunians.

Stephan R. Targan's work has appeared primarily in the following publication venues:

  • Gastroenterology
  • Inflammatory Bowel Diseases
  • The American Journal of Gastroenterology
  • Clinical Gastroenterology and Hepatology
  • International Journal of Molecular Sciences

Best Publications

  • Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

    Luke Jostins;Stephan Ripke;Rinse K Weersma;Richard H Duerr

  • A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease. Crohn's Disease cA2 Study Group.

    S. R. Targan;S. B. Hanauer;S. J. H. Van Deventer;L. Mayer

  • Toward an Integrated Clinical, Molecular and Serological Classification of Inflammatory Bowel Disease: Report of a Working Party of the 2005 Montreal World Congress of Gastroenterology

    Mark S. Silverberg;Jack Satsangi;Tariq Ahmad;Ian D. R. Arnott

  • A Genome-Wide Association Study Identifies IL23R as an Inflammatory Bowel Disease Gene

    Richard H. Duerr;Kent D. Taylor;Steven R. Brant;Steven R. Brant;John D. Rioux;John D. Rioux

  • Infliximab for the treatment of fistulas in patients with Crohn's disease.

    D.H. Present;P.J. Rutgeerts;S.R. Targan;S.B. Hanauer

  • Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

    Jeffrey C. Barrett;Sarah Hansoul;Dan L. Nicolae;Judy H. Cho

  • Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

    Andre Franke;Dermot P B McGovern;Jeffrey C. Barrett;Kai Wang

  • Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis

    John D. Rioux;John D. Rioux;Ramnik J. Xavier;Kent D. Taylor;Mark S. Silverberg

  • Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47.

    Carl A. Anderson;Gabrielle Boucher;Charlie W. Lees;Andre Franke

  • Efficacy and safety of retreatment with anti-tumor necrosis factor antibody (infliximab) to maintain remission in Crohn's disease.

    Paul Rutgeerts;G D'Haens;S Targan;E Vasiliauskas

  • Ustekinumab Induction and Maintenance Therapy in Refractory Crohn's Disease

    William J. Sandborn;Christopher Gasink;Long Long Gao;Marion A. Blank

  • Pharmacogenomics and metabolite measurement for 6-mercaptopurine therapy in inflammatory bowel disease

    Marla C. Dubinsky;Stéphanie Lamothe;Hui Ying Yang;Stephan R. Targan

  • Natalizumab induction and maintenance therapy for Crohn's disease.

    William J. Sandborn;Jean Frédéric Colombel;Roberts Enns;Brian G. Feagan

  • Role of Cytokines in the Pathogenesis of Inflammatory Bowel Disease

    Konstantinos A. Papadakis;Stephan R. Targan

  • Bacterial flagellin is a dominant antigen in Crohn disease

    Michael J. Lodes;Yingzi Cong;Charles O. Elson;Raodoh Mohamath

  • Genome-wide association identifies multiple ulcerative colitis susceptibility loci

    Dermot P.B. McGovern;Agnès Gardet;Leif Törkvist;Philippe Goyette

  • Anti-Saccharomyces cerevisiae mannan antibodies combined with antineutrophil cytoplasmic autoantibodies in inflammatory bowel disease: prevalence and diagnostic role

    J F Quinton;B Sendid;D Reumaux;P Duthilleul

  • Natalizumab for the Treatment of Active Crohn’s Disease: Results of the ENCORE Trial

    Stephan R. Targan;Brian G. Feagan;Richard N. Fedorak;Bret A. Lashner

  • A distinct subset of antineutrophil cytoplasmic antibodies is associated with inflammatory bowel disease

    Andrew Saxon;Fergus Shanahan;Carol Landers;Tomas Ganz

  • Gene-microbiota interactions contribute to the pathogenesis of inflammatory bowel disease.

    Hiutung Chu;Arya Khosravi;Indah P. Kusumawardhani;Alice H.K. Kwon

  • Association of antibody responses to microbial antigens and complications of small bowel Crohn's disease

    William S. Mow;Eric A. Vasiliauskas;Ying Chao Lin;Phillip R. Fleshner

Frequent Co-Authors

Dermot P.B. McGovern
Dermot P.B. McGovern Cedars-Sinai Medical Center
Marla Dubinsky
Marla Dubinsky Icahn School of Medicine at Mount Sinai
Jerome I. Rotter
Jerome I. Rotter UCLA Medical Center
Carol J. Landers
Carol J. Landers Cedars-Sinai Medical Center
Kent D. Taylor
Kent D. Taylor David Geffen School of Medicine at UCLA
Talin Haritunians
Talin Haritunians Cedars-Sinai Medical Center
Jonathan Braun
Jonathan Braun Cedars-Sinai Medical Center
William J. Sandborn
William J. Sandborn University of California, San Diego
Fergus Shanahan
Fergus Shanahan National University of Ireland
Maria T. Abreu
Maria T. Abreu University of Miami

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