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Overview

Marla Dubinsky is affiliated with the Icahn School of Medicine at Mount Sinai in the United States. Their research focuses extensively on inflammatory bowel diseases, combining expertise in medicine, biochemistry, genetics, and molecular biology.

Their work spans multiple subfields including genetics, epidemiology, surgery, immunology, and infectious diseases. Central topics of study encompass inflammatory bowel disease, microscopic colitis, eosinophilic esophagitis, immunodeficiency and autoimmune disorders, pregnancy and medication impact, Helicobacter pylori-related gastroenterology studies, and other autoimmune and inflammatory disorders.

Dubinsky has contributed to research published predominantly in the following venues:

  • Gastroenterology
  • The American Journal of Gastroenterology
  • Journal of Crohn's and Colitis
  • Inflammatory Bowel Diseases
  • Crohn's & Colitis 360

Frequent collaborators include:

  • Remo Panaccione
  • Bruce E. Sands
  • Séverine Vermeire
  • Ryan C. Ungaro
  • Jean-Frédéric Colombel

Significant recent papers by Dubinsky include:

  • "Risankizumab as induction therapy for Crohn's disease: results from the phase 3 ADVANCE and MOTIVATE induction trials," 2022, The Lancet
  • "Etrasimod as induction and maintenance therapy for ulcerative colitis (ELEVATE): two randomised, double-blind, placebo-controlled, phase 3 studies," 2023, The Lancet
  • "Pregnancy and Neonatal Outcomes After Fetal Exposure to Biologics and Thiopurines Among Women With Inflammatory Bowel Disease," 2020, Gastroenterology
  • "Risankizumab as maintenance therapy for moderately to severely active Crohn's disease: results from the multicentre, randomised, double-blind, placebo-controlled, withdrawal phase 3 FORTIFY maintenance trial," 2022, The Lancet
  • "Mirikizumab as Induction and Maintenance Therapy for Ulcerative Colitis," 2023, New England Journal of Medicine

Best Publications

  • Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

    Luke Jostins;Stephan Ripke;Rinse K Weersma;Richard H Duerr

  • Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

    Andre Franke;Dermot P B McGovern;Jeffrey C. Barrett;Kai Wang

  • Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE): Determining Therapeutic Goals for Treat-to-Target.

    L. Peyrin-Biroulet;W. Sandborn;B. E. Sands;W. Reinisch;W. Reinisch

  • Pediatric modification of the Montreal classification for inflammatory bowel disease: the Paris classification.

    Arie Levine;Anne Griffiths;James Markowitz;David C Wilson

  • Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47.

    Carl A. Anderson;Gabrielle Boucher;Charlie W. Lees;Andre Franke

  • Pharmacogenomics and metabolite measurement for 6-mercaptopurine therapy in inflammatory bowel disease

    Marla C. Dubinsky;Stéphanie Lamothe;Hui Ying Yang;Stephan R. Targan

  • Interactions Between Commensal Fungi and the C-Type Lectin Receptor Dectin-1 Influence Colitis

    Iliyan D. Iliev;Vincent A. Funari;Vincent A. Funari;Kent D. Taylor;Quoclinh Nguyen

  • Single-Cell Analysis of Crohn's Disease Lesions Identifies a Pathogenic Cellular Module Associated with Resistance to Anti-TNF Therapy.

    Jerome C. Martin;Christie Chang;Gilles Boschetti;Ryan Ungaro

  • Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease.

    Manuel A. Rivas;Manuel A. Rivas;Manuel A. Rivas;Mélissa Beaudoin;Agnes Gardet;Christine Stevens

  • Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study

    Isabelle Cleynen;Isabelle Cleynen;Gabrielle Boucher;Luke Jostins;Luke Jostins;Luke Jostins;L Philip Schumm

  • Genome-wide association identifies multiple ulcerative colitis susceptibility loci

    Dermot P.B. McGovern;Agnès Gardet;Leif Törkvist;Philippe Goyette

  • Prediction of complicated disease course for children newly diagnosed with Crohn's disease: a multicentre inception cohort study

    Subra Kugathasan;Lee A. Denson;Thomas D. Walters;Mi Ok Kim

  • Differentiating ulcerative colitis from Crohn disease in children and young adults: report of a working group of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the Crohn's and Colitis Foundation of America.

    Athos Bousvaros

  • Common variants at five new loci associated with early-onset inflammatory bowel disease.

    Marcin Imielinski;Robert N. Baldassano;Anne Griffiths;Richard K. Russell

  • Placental transfer of anti-tumor necrosis factor agents in pregnant patients with inflammatory bowel disease.

    Uma Mahadevan;Douglas C. Wolf;Marla Dubinsky;Antoine Cortot

  • 6-MP metabolite profiles provide a biochemical explanation for 6-MP resistance in patients with inflammatory bowel disease.

    Marla C. Dubinsky;Huiying Yang;Philip V. Hassard;Ernest G. Seidman

  • A common missense variant in NUDT15 confers susceptibility to thiopurine-induced leukopenia

    Suk-Kyun Yang;Myunghee Hong;Jiwon Baek;Hyunchul Choi

  • Diagnostic accuracy of serological assays in pediatric inflammatory bowel disease

    Frank M. Ruemmele;Stephan R. Targan;Galith Levy;Maria Dubinsky

  • Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease

    Dermot P.B. McGovern;Michelle R. Jones;Kent D. Taylor;Kristin Marciante

  • Effect of medication dosing frequency on adherence in chronic diseases.

    Sameer D Saini;Philip Schoenfeld;Kellee Kaulback;Marla C Dubinsky

Frequent Co-Authors

Stephan R. Targan
Stephan R. Targan Cedars-Sinai Medical Center
Dermot P.B. McGovern
Dermot P.B. McGovern Cedars-Sinai Medical Center
Jeffrey S. Hyams
Jeffrey S. Hyams University of Connecticut
Subra Kugathasan
Subra Kugathasan Emory University
Jean-Frederic Colombel
Jean-Frederic Colombel Icahn School of Medicine at Mount Sinai
Jerome I. Rotter
Jerome I. Rotter UCLA Medical Center
Anne M. Griffiths
Anne M. Griffiths University of Toronto
Robert N. Baldassano
Robert N. Baldassano Children's Hospital of Philadelphia
Kent D. Taylor
Kent D. Taylor David Geffen School of Medicine at UCLA
Lee A. Denson
Lee A. Denson Cincinnati Children's Hospital Medical Center

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