World's Best Scientists 2026 revealed!
Andre Franke

Andre Franke

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Genetics
Germany
2026
Award Badge
Medicine
Germany
2026

D-Index & Metrics

Genetics

D-Index
155
Citations
91847
World Ranking
116
National Ranking
9

Medicine

D-Index
155
Citations
94177
World Ranking
961
National Ranking
46

Research.com Recognitions

  • 2026 - Research.com Genetics in Germany Leader Award
  • 2026 - Research.com Medicine in Germany Leader Award
  • 2025 - Research.com Genetics in Germany Leader Award
  • 2024 - Research.com Genetics in Germany Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in Germany Leader Award
  • 2023 - Research.com Genetics in Germany Leader Award

Overview

Andre Franke is affiliated with Kiel University in Germany and has contributed extensively to the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans a variety of subfields, including Molecular Biology, Genetics, Immunology, Physiology, and Infectious Diseases.

The scientist's research topics include:

  • Gut microbiota and health
  • Inflammatory Bowel Disease
  • Diet and metabolism studies
  • Liver Diseases and Immunity
  • Epigenetics and DNA Methylation
  • COVID-19 Clinical Research Studies
  • T-cell and B-cell Immunology

Andre Franke has a notable presence in several publication venues, frequently contributing to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Crohn's and Colitis
  • Scientific Reports
  • Nature Communications
  • Gut

Among their recent papers are:

  • The mutational constraint spectrum quantified from variation in 141,456 humans (2020, Nature)
  • Large-scale association analyses identify host factors influencing human gut microbiome composition (2021, Nature Genetics)
  • A genomic mutational constraint map using variation in 76,156 human genomes (2023, Nature)
  • Dense sampling of bird diversity increases power of comparative genomics (2020, Nature)
  • Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology (2021, Nature Genetics)

Frequent co-authors include:

  • Corinna Bang
  • Wolfgang Lieb
  • Stefan Schreiber
  • Malte Rühlemann
  • Matthias Laudes

Best Publications

  • Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

    Luke Jostins;Stephan Ripke;Rinse K Weersma;Richard H Duerr

  • Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

    Andre Franke;Dermot P B McGovern;Jeffrey C. Barrett;Kai Wang

  • Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

    Stephen Sawcer;Garrett Hellenthal;Matti Pirinen;Chris C. A. Spencer

  • A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1

    Jochen Hampe;Andre Franke;Philip Rosenstiel;Philip Rosenstiel;Andreas Till

  • Microbial Exposure During Early Life Has Persistent Effects on Natural Killer T Cell Function

    Torsten Olszak;Dingding An;Sebastian Zeissig;Miguel Pinilla Vera

  • Genomewide Association Study of Severe Covid-19 with Respiratory Failure.

    David Ellinghaus;Frauke Degenhardt;Luis Bujanda;Maria Buti

  • Large-scale association analyses identify host factors influencing human gut microbiome composition

    Alexander Kurilshikov;Carolina Medina-Gomez;Rodrigo Bacigalupe;Djawad Radjabzadeh

  • Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47.

    Carl A. Anderson;Gabrielle Boucher;Charlie W. Lees;Andre Franke

  • XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease

    Arthur Kaser;Ann-Hwee Lee;Andre Franke;Jonathan N. Glickman

  • Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

    Ashley H. Beecham;Nikolaos A. Patsopoulos;Nikolaos A. Patsopoulos;Dionysia K. Xifara;Mary F. Davis

  • Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

    Lam C. Tsoi;Sarah L. Spain;Sarah L. Spain;Jo Knight;Eva Ellinghaus;Eva Ellinghaus

  • New loci associated with kidney function and chronic kidney disease

    Anna Köttgen;Anna Köttgen;Cristian Pattaro;Carsten A. Böger;Christian Fuchsberger

  • Autosomal dominant immune dysregulation syndrome in humans with CTLA4 mutations.

    Desireé Schubert;Desireé Schubert;Claudia Bode;Rupert Kenefeck;Tie Zheng Hou

  • Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease.

    Manuel A. Rivas;Manuel A. Rivas;Manuel A. Rivas;Mélissa Beaudoin;Agnes Gardet;Christine Stevens

  • The dynamic genome of Hydra

    Jarrod A. Chapman;Ewen F. Kirkness;Oleg Simakov;Oleg Simakov;Steven E. Hampson

  • Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci

    David Ellinghaus;Luke Jostins;Sarah L. Spain;Adrian Cortes

  • Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study

    Isabelle Cleynen;Isabelle Cleynen;Gabrielle Boucher;Luke Jostins;Luke Jostins;Luke Jostins;L Philip Schumm

  • Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility

    Andre Franke;Tobias Balschun;Tom H Karlsen;Jurgita Sventoraityte

  • Meta-analysis and imputation refines the association of 15q25 with smoking quantity

    Jason Z. Liu;Federica Tozzi;Dawn M. Waterworth;Sreekumar G. Pillai

  • 15q13.3 microdeletions increase risk of idiopathic generalized epilepsy

    Ingo Helbig;Heather C. Mefford;Andrew J. Sharp;Michel Guipponi

Frequent Co-Authors

Stefan Schreiber
Stefan Schreiber Kiel University
Wolfgang Lieb
Wolfgang Lieb Kiel University
David Ellinghaus
David Ellinghaus Kiel University
Tom H. Karlsen
Tom H. Karlsen Oslo University Hospital
Philip Rosenstiel
Philip Rosenstiel Kiel University
Christian Gieger
Christian Gieger Helmholtz Zentrum München
Tonu Esko
Tonu Esko University of Tartu
Stephan Weidinger
Stephan Weidinger Kiel University
James T. Elder
James T. Elder University of Michigan–Ann Arbor
Michael Krawczak
Michael Krawczak Kiel University

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