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David Ellinghaus

David Ellinghaus

D-Index & Metrics

Genetics

D-Index
62
Citations
35917
World Ranking
2934
National Ranking
205

Overview

David Ellinghaus is affiliated with Kiel University in Germany and has contributed extensively to research in the fields of medicine and biochemistry, genetics, and molecular biology. Their work primarily focuses on molecular biology, genetics, and immunology, with additional interests in surgery and epidemiology.

Ellinghaus's research covers a range of topics, including genetic associations and epidemiology, inflammatory bowel disease, IL-33, ST2, and ILC pathways, gut microbiota and health, RNA modifications and cancer, immune cell function and interaction, and Helicobacter pylori-related gastroenterology studies.

Notable recent publications by Ellinghaus include:

  • Genomewide Association Study of Severe Covid-19 with Respiratory Failure, 2020, New England Journal of Medicine
  • Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19, 2020, Immunity
  • Whole-genome sequencing of a sporadic primary immunodeficiency cohort, 2020, Nature
  • Detailed stratified GWAS analysis for severe COVID-19 in four European populations, 2022, Human Molecular Genetics
  • Host genetic factors related to innate immunity, environmental sensing and cellular functions are associated with human skin microbiota, 2022, Nature Communications

They frequently collaborate with other researchers, including André Franke, Lars Wienbrandt, Frauke Degenhardt, Eike Matthias Wacker, and Florian Uellendahl-Werth.

Ellinghaus's research has been published predominantly in venues such as bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Gut, Frontiers in Medicine, and Nature, reflecting a consistent emphasis on high-impact scientific outlets.

Best Publications

  • Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

    Luke Jostins;Stephan Ripke;Rinse K Weersma;Richard H Duerr

  • Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

    Andre Franke;Dermot P B McGovern;Jeffrey C. Barrett;Kai Wang

  • Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

    Stephen Sawcer;Garrett Hellenthal;Matti Pirinen;Chris C. A. Spencer

  • Genomewide Association Study of Severe Covid-19 with Respiratory Failure.

    David Ellinghaus;Frauke Degenhardt;Luis Bujanda;Maria Buti

  • LTRharvest , an efficient and flexible software for de novo detection of LTR retrotransposons

    David Ellinghaus;Stefan Kurtz;Ute Willhoeft

  • Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47.

    Carl A. Anderson;Gabrielle Boucher;Charlie W. Lees;Andre Franke

  • New loci associated with kidney function and chronic kidney disease

    Anna Köttgen;Anna Köttgen;Cristian Pattaro;Carsten A. Böger;Christian Fuchsberger

  • Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease.

    Manuel A. Rivas;Manuel A. Rivas;Manuel A. Rivas;Mélissa Beaudoin;Agnes Gardet;Christine Stevens

  • Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci

    David Ellinghaus;Luke Jostins;Sarah L. Spain;Adrian Cortes

  • Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility

    Andre Franke;Tobias Balschun;Tom H Karlsen;Jurgita Sventoraityte

  • Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota

    Jun Wang;Louise B Thingholm;Jurgita Skiecevičienė;Philipp Rausch;Philipp Rausch

  • A genome-wide association study confirms PNPLA3 and identifies TM6SF2 and MBOAT7 as risk loci for alcohol-related cirrhosis

    Stephan Buch;Felix Stickel;Eric Trépo;Michael Way

  • Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases A Mendelian Randomization Study

    Philip C Haycock;Stephen Burgess;Aayah Nounu

  • Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

    Cristian Pattaro;Alexander Teumer;Mathias Gorski;Audrey Y. Chu

  • New gene functions in megakaryopoiesis and platelet formation

    Christian Gieger;Aparna Radhakrishnan;Ana Cvejic;Weihong Tang

  • Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2

    Eva Ellinghaus;David Ellinghaus;Philip E Stuart;Rajan P Nair

  • Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

    Valérie Turcot;Yingchang Lu;Yingchang Lu;Heather M Highland;Heather M Highland;Claudia Schurmann

  • Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis

    Jimmy Z Liu;Johannes Roksund Hov;Trine Folseraas;Trine Folseraas;Eva Ellinghaus

  • Combined Analysis of Genome-wide Association Studies for Crohn Disease and Psoriasis Identifies Seven Shared Susceptibility Loci

    David Ellinghaus;Eva Ellinghaus;Rajan P. Nair;Philip E. Stuart

  • Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis.

    Lavinia Paternoster;Marie Standl;Chih-Mei Chen;Adaikalavan Ramasamy

Frequent Co-Authors

Andre Franke
Andre Franke Kiel University
Stefan Schreiber
Stefan Schreiber Kiel University
Christian Gieger
Christian Gieger Helmholtz Zentrum München
Tom H. Karlsen
Tom H. Karlsen Oslo University Hospital
Wolfgang Lieb
Wolfgang Lieb Kiel University
Tonu Esko
Tonu Esko University of Tartu
John D. Rioux
John D. Rioux University of Montreal
Philip Rosenstiel
Philip Rosenstiel Kiel University
Rinse K. Weersma
Rinse K. Weersma University Medical Center Groningen
André G. Uitterlinden
André G. Uitterlinden Erasmus University Rotterdam

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