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Gregory S. Hageman

Gregory S. Hageman

D-Index & Metrics

Medicine

D-Index
75
Citations
26095
World Ranking
19026
National Ranking
9487

Overview

Gregory S. Hageman is affiliated with the University of Utah in the United States and primarily works within the field of medicine. Their research has a significant focus on ophthalmology, with substantial contributions to subfields including radiology, nuclear medicine and imaging, molecular biology, neurology, and immunology.

The scientist's main areas of study cover a range of retinal and ocular topics such as retinal diseases and treatments, retinal imaging and analysis, retinal development and disorders, glaucoma and retinal disorders, corneal surgery and treatments, corneal surgery and disorders, and cerebrovascular and genetic disorders.

Gregory S. Hageman has published several recent papers, including:

  • Cell atlas of the human ocular anterior segment: Tissue-specific and shared cell types, 2022, Proceedings of the National Academy of Sciences
  • Chromosome 10q26-driven age-related macular degeneration is associated with reduced levels of HTRA1 in human retinal pigment epithelium, 2021, Proceedings of the National Academy of Sciences
  • Systems genomics in age-related macular degeneration, 2022, Experimental Eye Research
  • Transcriptomic analysis of the ocular posterior segment completes a cell atlas of the human eye, 2023, Proceedings of the National Academy of Sciences
  • Protective chromosome 1q32 haplotypes mitigate risk for age-related macular degeneration associated with the CFH-CFHR5 and ARMS2/HTRA1 loci, 2021, Human Genomics

Frequent publication venues for their work include:

  • Proceedings of the National Academy of Sciences
  • Experimental Eye Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Scientific Reports
  • Ophthalmology Science

The scientist collaborates regularly with several coauthors, with frequent partnerships including Moussa A. Zouache, Burt T. Richards, Christian Pappas, Chris Pappas, and Jill L. Hageman.

Best Publications

  • A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration

    Gregory S. Hageman;Don H. Anderson;Lincoln V. Johnson;Lisa S. Hancox

  • An Integrated Hypothesis That Considers Drusen as Biomarkers of Immune-Mediated Processes at the RPE-Bruch's Membrane Interface in Aging and Age-Related Macular Degeneration

    Gregory S. Hageman;Phil J. Luthert;N.H. Victor Chong;N.H. Victor Chong;Lincoln V. Johnson

  • A role for local inflammation in the formation of drusen in the aging eye.

    Don H Anderson;Robert F Mullins;Gregory S Hageman;Lincoln V Johnson

  • Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration

    Bert Gold;Joanna E Merriam;Jana Zernant;Lisa S Hancox

  • Drusen associated with aging and age-related macular degeneration contain proteins common to extracellular deposits associated with atherosclerosis, elastosis, amyloidosis, and dense deposit disease

    Robert F. Mullins;Stephen R. Russell;Don H. Anderson;Gregory S. Hageman

  • Seven new loci associated with age-related macular degeneration

    Lars G. Fritsche;Lars G. Fritsche;Wei Chen;Wei Chen;Matthew Schu;Brian L. Yaspan

  • Age-related macular degeneration--emerging pathogenetic and therapeutic concepts.

    Karen M. Gehrs;Don H. Anderson;Lincoln V. Johnson;Gregory S. Hageman

  • The pivotal role of the complement system in aging and age-related macular degeneration: hypothesis re-visited.

    Don H. Anderson;Monte J. Radeke;Natasha B. Gallo;Ethan A. Chapin

  • The Role of Inflammation in the Pathogenesis of Age-related Macular Degeneration

    Larry A. Donoso;David Kim;Arcilee Frost;Alston Callahan

  • Age-Related Macular Degeneration (AMD)

    Gregory S. Hageman;Karen Gehrs;Lincoln V. Johnson;Don Anderson

  • A single EFEMP1 mutation associated with both Malattia Leventinese and Doyne honeycomb retinal dystrophy.

    Edwin M. Stone;Andrew J. Lotery;Francis L. Munier;Elise Héon

  • Membranoproliferative Glomerulonephritis Type II (Dense Deposit Disease): An Update

    Gerald B. Appel;H. Terence Cook;Gregory Hageman;J. Charles Jennette

  • Characterization of beta amyloid assemblies in drusen: the deposits associated with aging and age-related macular degeneration

    Don H. Anderson;Kevin C. Talaga;Alexander J. Rivest;Ernesto Barron

  • Non-secretion of mutant proteins of the glaucoma gene myocilin in cultured trabecular meshwork cells and in aqueous humor

    Nasreen Jacobson;Michael Andrews;Allan R. Shepard;Darryl Nishimura

  • Local cellular sources of apolipoprotein E in the human retina and retinal pigmented epithelium: implications for the process of drusen formation.

    Don H Anderson;Shiro Ozaki;Matthew Nealon;Jay Neitz

  • Ophthalmic Drug Delivery Systems for the Treatment of Retinal Diseases: Basic Research to Clinical Applications

    Henry F. Edelhauser;Cheryl L. Rowe-Rendleman;Michael R. Robinson;Daniel G. Dawson

  • Variations in the complement regulatory genes factor H (CFH) and factor H related 5 (CFHR5) are associated with membranoproliferative glomerulonephritis type II (dense deposit disease)

    Maria Asuncion Abrera-Abeleda;Carla Nishimura;Jenna L.H. Smith;Sanjjev Sethi

  • Individuals homozygous for the age-related macular degeneration risk-conferring variant of complement factor H have elevated levels of CRP in the choroid

    P.T. Johnson;K.E. Betts;M.J. Radeke;G.S. Hageman

  • New Approaches to the Treatment of Dense Deposit Disease

    Richard J.H. Smith;Jessy Alexander;Paul N. Barlow;Marina Botto

  • PERSPECTIVE A Role for Local Inflammation in the Formation of Drusen in the Aging Eye

    Don H. Anderson;Robert F. Mullins;Gregory S. Hageman;Lincoln V. Johnson

Frequent Co-Authors

Robert F. Mullins
Robert F. Mullins University of Iowa
Robyn H. Guymer
Robyn H. Guymer University of Melbourne
Paul S. Bernstein
Paul S. Bernstein University of Utah
Edwin M. Stone
Edwin M. Stone University of Iowa
Richard J.H. Smith
Richard J.H. Smith University of Iowa
Rando Allikmets
Rando Allikmets Columbia University
Paul N. Baird
Paul N. Baird University of Melbourne
Debra A. Schaumberg
Debra A. Schaumberg University of Utah
Lindsay A. Farrer
Lindsay A. Farrer Boston University
Val C. Sheffield
Val C. Sheffield University of Iowa

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