A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration
Gregory S. Hageman;Don H. Anderson;Lincoln V. Johnson;Lisa S. Hancox.
Proceedings of the National Academy of Sciences of the United States of America (2005)
2239 Citations
An Integrated Hypothesis That Considers Drusen as Biomarkers of Immune-Mediated Processes at the RPE-Bruch's Membrane Interface in Aging and Age-Related Macular Degeneration
Gregory S. Hageman;Phil J. Luthert;N.H. Victor Chong;N.H. Victor Chong;Lincoln V. Johnson.
Progress in Retinal and Eye Research (2001)
1499 Citations
A role for local inflammation in the formation of drusen in the aging eye.
Don H Anderson;Robert F Mullins;Gregory S Hageman;Lincoln V Johnson.
American Journal of Ophthalmology (2002)
1288 Citations
Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration
Bert Gold;Joanna E Merriam;Jana Zernant;Lisa S Hancox.
Nature Genetics (2006)
1275 Citations
Drusen associated with aging and age-related macular degeneration contain proteins common to extracellular deposits associated with atherosclerosis, elastosis, amyloidosis, and dense deposit disease
Robert F. Mullins;Stephen R. Russell;Don H. Anderson;Gregory S. Hageman.
The FASEB Journal (2000)
820 Citations
Seven new loci associated with age-related macular degeneration
Lars G. Fritsche;Lars G. Fritsche;Wei Chen;Wei Chen;Matthew Schu;Brian L. Yaspan.
Nature Genetics (2013)
774 Citations
Age-related macular degeneration--emerging pathogenetic and therapeutic concepts.
Karen M. Gehrs;Don H. Anderson;Lincoln V. Johnson;Gregory S. Hageman.
Annals of Medicine (2006)
771 Citations
The pivotal role of the complement system in aging and age-related macular degeneration: hypothesis re-visited.
Don H. Anderson;Monte J. Radeke;Natasha B. Gallo;Ethan A. Chapin.
Progress in Retinal and Eye Research (2010)
740 Citations
The Role of Inflammation in the Pathogenesis of Age-related Macular Degeneration
Larry A. Donoso;David Kim;Arcilee Frost;Alston Callahan.
Survey of Ophthalmology (2006)
676 Citations
Age-Related Macular Degeneration (AMD)
Gregory S. Hageman;Karen Gehrs;Lincoln V. Johnson;Don Anderson.
(2008)
530 Citations
