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Neuroscience

D-Index
59
Citations
10276
World Ranking
4063
National Ranking
1848

Overview

Anthony S. Basile is affiliated with the National Institutes of Health in the United States. Their research primarily focuses on neuroscience and medicine, with significant contributions to molecular biology, cellular and molecular neuroscience, and radiology, nuclear medicine, and imaging. Additional work encompasses cognitive neuroscience and cardiology and cardiovascular medicine.

The scientist's research topics cover a range of areas including:

  • Neuroscience and Neuropharmacology Research
  • Receptor Mechanisms and Signaling
  • Advanced MRI Techniques and Applications
  • Phosphodiesterase function and regulation
  • Neural and Behavioral Psychology Studies
  • Cardiac electrophysiology and arrhythmias
  • Advanced NMR Techniques and Applications

Their publication record includes papers in frequently appearing venues such as Neurology, Science Translational Medicine, SSRN Electronic Journal, Alzheimer's & Dementia, and NMR in Biomedicine. Notable papers authored or coauthored by Basile include:

  • The PET tracer [ 11 C]MK-6884 quantifies M4 muscarinic receptor in rhesus monkeys and patients with Alzheimer's disease, 2022, Science Translational Medicine
  • Validation of a Suite of ERP and QEEG Biomarkers in a Pre-Competitive, Industry-Led Study in Subjects with Schizophrenia and Healthy Volunteers, 2022, SSRN Electronic Journal
  • [11C]MK-6884 PET Tracer for M4 Muscarinic Cholinergic Receptors in Alzheimer's Disease: Comparison with [18F]FDG PET (2640), 2020, Neurology
  • The novel M4 PAM PET tracer [11C] MK-6884: a novel biomarker for measuring target engagement of muscarinic M4 positive allosteric modulators (PAMs) as well as cholinergic tone in patients with Alzheimer's disease, 2022, Alzheimer's & Dementia
  • Reproducibility of the Determination of 13C-Labeling of Glutamate and Glutamine in the Human Brain Using selPOCE-MRS at 7 T Upon [U-13C]-Labeled Glucose Infusion, 2025, NMR in Biomedicine

Frequent collaborators in their work include:

  • Wenping Li
  • Joseph C. Masdeu
  • Eric D. Hostetler
  • Jason M. Uslaner
  • Inge De Lepeleire

Best Publications

  • Peripheral benzodiazepine receptors and mitochondrial function.

    Pierre Casellas;Sylvaine Galiegue;Anthony S Basile

  • Characterization of central inhibitory muscarinic autoreceptors by the use of muscarinic acetylcholine receptor knock-out mice

    Weilie Zhang;Anthony S. Basile;Jesus Gomeza;Laura A. Volpicelli

  • Early increases in TNF-α, IL-6 and IL-1β levels following transient cerebral ischemia in gerbil brain

    Kuniaki Saito;Kazuhiko Suyama;Keiji Nishida;Yoshitatsu Sei

  • Activation of microglia by secreted amyloid precursor protein evokes release of glutamate by cystine exchange and attenuates synaptic function.

    Steven W. Barger;Anthony S. Basile

  • Multiple muscarinic acetylcholine receptor subtypes modulate striatal dopamine release, as studied with M1-M5 muscarinic receptor knock-out mice.

    Weilie Zhang;Masahisa Yamada;Jesus Gomeza;Anthony S. Basile

  • M2 muscarinic acetylcholine receptor knock-out mice show deficits in behavioral flexibility, working memory, and hippocampal plasticity.

    Thomas Seeger;Irina Fedorova;Fang Zheng;Tsuyoshi Miyakawa

  • Deletion of the M5 muscarinic acetylcholine receptor attenuates morphine reinforcement and withdrawal but not morphine analgesia.

    Anthony S. Basile;Irina Fedorova;Agustin Zapata;Xiaoguang Liu

  • Induction of serine racemase expression and D -serine release from microglia by amyloid β-peptide

    Sheng-Zhou Wu;Angela M Bodles;Mandy M Porter;W Sue T Griffin

  • Elevated Brain Concentrations of 1, 4-Benzodiazepines in Fulminant Hepatic Failure

    A. S. Basile;R. D. Hughes;P. M. Harrison;Y. Murata

  • N-methyl-D-aspartate antagonists limit aminoglycoside antibiotic-induced hearing loss.

    Anthony S. Basile;Jer-Min Huang;Chen Xie;Douglas Webster

  • Evaluation of Muscarinic Agonist-Induced Analgesia in Muscarinic Acetylcholine Receptor Knockout Mice

    Alokesh Duttaroy;Jesus Gomeza;Jai-Wei Gan;Nasir Siddiqui

  • Subcellular Localization of “Peripheral-Type” Binding Sites for Benzodiazepines in Rat Brain

    Anthony S. Basile;Phil Skolnick

  • The pathogenesis and treatment of hepatic encephalopathy: evidence for the involvement of benzodiazepine receptor ligands.

    A S Basile;E A Jones;P Skolnick

  • Ammonia and GABA‐ergic neurotransmission: Interrelated factors in the pathogenesis of hepatic encephalopathy

    A S Basile;E A Jones

  • Reversal of the behavioral and electrophysiological abnormalities of an animal model of hepatic encephalopathy by benzodiazepine receptor ligands.

    Sergio H. Gammal;Anthony S. Basile;David Geller;Phil Skolnick

  • Role for M5 muscarinic acetylcholine receptors in cocaine addiction.

    Anders Fink-Jensen;Irina Fedorova;Gitta Wörtwein;David P. D. Woldbye

  • Behavioral characterization of mice lacking the A3 adenosine receptor: sensitivity to hypoxic neurodegeneration.

    Irina M. Fedorova;Marlene A. Jacobson;Anthony Basile;Kenneth A. Jacobson

  • Skeletal muscle type ryanodine receptor is involved in calcium signaling in human B lymphocytes.

    Yoshitatsu Sei;Kathleen L. Gallagher;Anthony S. Basile

  • Internucleosomal DNA fragmentation in gerbil hippocampus following forebrain ischemia

    Yoshitatsu Sei;Dag K.J.E. Von Lubitz;Anthony S. Basile;Markus M. Borner

  • Group II metabotropic glutamate receptor activation attenuates traumatic neuronal injury and improves neurological recovery after traumatic brain injury.

    Jason W. Allen;Svetlana A. Ivanova;Lei Fan;Michael G. Espey

Frequent Co-Authors

Jacqueline N. Crawley
Jacqueline N. Crawley University of California, Davis
Robert K. Heaton
Robert K. Heaton University of California, San Diego
David H. Farb
David H. Farb Boston University
Dwaine F. Emerich
Dwaine F. Emerich Alkermes (Ireland)
Michael A. Rogawski
Michael A. Rogawski University of California, Davis
Tsuyoshi Miyakawa
Tsuyoshi Miyakawa Fujita Health University
Christian Alzheimer
Christian Alzheimer University of Erlangen-Nuremberg
Gitta Wörtwein
Gitta Wörtwein University of Copenhagen
Nicholas M. Boulis
Nicholas M. Boulis Emory University

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