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Biology and Biochemistry

D-Index
90
Citations
24138
World Ranking
2477
National Ranking
1307

Overview

Pamela Maher is affiliated with the Salk Institute for Biological Studies in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with notable focus on subfields such as Molecular Biology, Physiology, Pulmonary and Respiratory Medicine, Materials Chemistry, and Pharmacology.

The research topics covered extensively in their work include:

  • Ferroptosis and cancer prognosis
  • Alzheimer's disease research and treatments
  • Mitochondrial Function and Pathology
  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Cancer-related molecular mechanisms research

Recent scientific papers authored or coauthored by Pamela Maher include:

  • CMS121, a fatty acid synthase inhibitor, protects against excess lipid peroxidation and inflammation and alleviates cognitive loss in a transgenic mouse model of Alzheimer's disease, 2020, published in Redox Biology
  • Intracellular amyloid toxicity induces oxytosis/ferroptosis regulated cell death, 2020, published in Cell Death and Disease
  • Using the Oxytosis/Ferroptosis Pathway to Understand and Treat Age-Associated Neurodegenerative Diseases, 2020, published in Cell Chemical Biology
  • Preventing and Treating Neurological Disorders with the Flavonol Fisetin, 2020, published in Brain Plasticity
  • Natural products targeting mitochondria: emerging therapeutics for age-associated neurological disorders, 2020, published in Pharmacology & Therapeutics

Frequent coauthors associated with Pamela Maher's work are:

  • António Currais
  • David Soriano-Castell
  • Zhibin Liang
  • David Schubert
  • Salvador Soriano

The venues in which Pamela Maher publishes frequently include:

  • Free Radical Biology and Medicine
  • Antioxidants
  • The Cambridge Structural Database
  • Redox Biology
  • International Journal of Molecular Sciences

Best Publications

  • The Regulation of Reactive Oxygen Species Production during Programmed Cell Death

    Shirlee Tan;Yutaka Sagara;Yuanbin Liu;Pamela Maher

  • The cystine/glutamate antiporter system xc- in health and disease: From molecular mechanisms to novel therapeutic opportunities

    Jan Lewerenz;Sandra J. Hewett;Ying Huang;Maria Lambros

  • Chronic Glutamate Toxicity in Neurodegenerative Diseases—What is the Evidence?

    Jan Lewerenz;Pamela Maher

  • A Role for 12-lipoxygenase in Nerve Cell Death Caused by Glutathione Depletion

    Yonghong Li;Pamela Maher;David Schubert

  • Oxytosis: A novel form of programmed cell death.

    Shirlee Tan;David Schubert;Pamela Maher

  • Protein kinase C activation inhibits glutamate-induced cytotoxicity in a neuronal cell line

    John B. Davis;Pamela Maher

  • Oxidative stress induces a form of programmed cell death with characteristics of both apoptosis and necrosis in neuronal cells.

    Shirlee Tan;Malcolm Wood;Pamela Maher

  • The Role of Monoamine Metabolism in Oxidative Glutamate Toxicity

    Pamela Maher;John B. Davis

  • Flavonoid fisetin promotes ERK-dependent long-term potentiation and enhances memory.

    Pamela Maher;Tatsuhiro Akaishi;Kazuho Abe

  • Flavonoids protect human retinal pigment epithelial cells from oxidative-stress-induced death.

    Anne Hanneken;Fen Fen Lin;Jennifer Johnson;Pamela Maher

  • A comprehensive analysis of the distribution of FGF-2 and FGFR1 in the rat brain.

    Ana Maria Gonzalez;Martin Berry;Pamela A. Maher;Ann Logan

  • Nuclear Translocation of fibroblast growth factor (FGF) receptors in response to FGF-2.

    Pamela A. Maher

  • How Protein Kinase C Activation Protects Nerve Cells from Oxidative Stress-Induced Cell Death

    Pamela Maher

  • The regulation of glucose metabolism by HIF-1 mediates a neuroprotective response to amyloid beta peptide.

    Thomas Soucek;Robert Cumming;Richard Dargusch;Pamela Maher

  • Phosphotyrosine-containing proteins are concentrated in focal adhesions and intercellular junctions in normal cells

    Pamela A. Maher;Elena B. Pasquale;Jean Y. J. Wang;S. J. Singer

  • Importin beta-mediated nuclear import of fibroblast growth factor receptor: role in cell proliferation.

    John F. Reilly;Pamela A. Maher

  • ERK activation by the polyphenols fisetin and resveratrol provides neuroprotection in multiple models of Huntington's disease

    Pamela Maher;Richard Dargusch;Laszlo Bodai;Paul E. Gerard

  • Signaling by reactive oxygen species in the nervous system.

    P. Maher;D. Schubert

  • Effects of dimethyl fumarate on neuroprotection and immunomodulation

    Philipp Albrecht;Imane Bouchachia;Norbert Goebels;Nadine Henke

  • Cellular Mechanisms of Resistance to Chronic Oxidative Stress

    Yutaka Sagara;Richard Dargusch;David Chambers;John Davis

Frequent Co-Authors

David Schubert
David Schubert Salk Institute for Biological Studies
Wolfgang H. Fischer
Wolfgang H. Fischer Salk Institute for Biological Studies
Michal K. Stachowiak
Michal K. Stachowiak University at Buffalo, State University of New York
Andrew Baird
Andrew Baird University of California, San Diego
Paul A. Lapchak
Paul A. Lapchak Cedars-Sinai Medical Center
John B. Davis
John B. Davis University of Oxford
Oswald Quehenberger
Oswald Quehenberger University of California, San Diego
Ilse Smolders
Ilse Smolders Vrije Universiteit Brussel
Kazuho Abe
Kazuho Abe Musashino University
Elena B. Pasquale
Elena B. Pasquale Discovery Institute

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