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Biology and Biochemistry

D-Index
85
Citations
56621
World Ranking
3052
National Ranking
229

Overview

Christian Behl is affiliated with Johannes Gutenberg University of Mainz in Germany. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Within these broad fields, their work focuses significantly on Molecular Biology, Epidemiology, Cell Biology, Physiology, and Neurology.

Behl's main research topics include:

  • Autophagy in Disease and Therapy
  • Endoplasmic Reticulum Stress and Disease
  • Heat shock proteins research
  • Parkinson's Disease Mechanisms and Treatments
  • Alzheimer's disease research and treatments
  • Calcium signaling and nucleotide metabolism
  • Sirtuins and Resveratrol in Medicine

Among recent papers authored with Behl's collaboration or contribution are:

  • At the Crossroads of Apoptosis and Autophagy: Multiple Roles of the Co-Chaperone BAG3 in Stress and Therapy Resistance of Cancer, 2020, published in Cells
  • Novel Insights into the Cellular Localization and Regulation of the Autophagosomal Proteins LC3A, LC3B and LC3C, 2020, published in Cells
  • Lipid and protein content profiling of isolated native autophagic vesicles, 2022, published in EMBO Reports
  • The Sigma-1 Receptor at the Crossroad of Proteostasis, Neurodegeneration, and Autophagy, 2020, published in Trends in Neurosciences
  • The selective degradation of sirtuins via macroautophagy in the MPP+ model of Parkinson's disease is promoted by conserved oxidation sites, 2021, published in Cell Death Discovery

Frequent co-authors collaborating with Behl include:

  • Hagen Körschgen
  • Marius W. Baeken
  • Andreas Kern
  • Albrecht M. Clement
  • Daniel Schmitt

Their work has been commonly published in several key venues such as:

  • Journal of Cellular Biochemistry
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cells
  • Trends in Neurosciences
  • Journal of Biological Chemistry

Christian Behl's research encompasses extensive investigation into cellular stress responses, particularly focusing on autophagy and mechanisms linked to neurodegenerative diseases like Parkinson's and Alzheimer's. The intersection of proteostasis, molecular chaperones, and disease pathways appears as a recurrent theme in their publications.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Hydrogen peroxide mediates amyloid beta protein toxicity.

    C. Behl;J.B. Davis;R. Lesley;D. Schubert

  • CB1 cannabinoid receptors and on-demand defense against excitotoxicity.

    Giovanni Marsicano;Sharon Goodenough;Sharon Goodenough;Krisztina Monory;Heike Hermann

  • Neuroprotection against Oxidative Stress by Estrogens: Structure-Activity Relationship

    Christian Behl;Thomas Skutella;Frank Lezoualc’H;Anke Post

  • 17-β Estradiol Protects Neurons from Oxidative Stress-Induced Cell Death in Vitro

    C. Behl;M. Widmann;T. Trapp;F. Holsboer

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Vitamin E protects nerve cells from amyloid βprotein toxicity

    Christian Behl;John Davis;Greg M. Cole;David Schubert

  • Ubiquitin-Dependent And Independent Signals In Selective Autophagy.

    Aliaksandr Khaminets;Christian Behl;Ivan Dikic

  • Oestrogen as a neuroprotective hormone

    Christian Behl

  • ALZHEIMER'S DISEASE AND OXIDATIVE STRESS : IMPLICATIONS FOR NOVEL THERAPEUTIC APPROACHES

    Christian Behl

  • Protein quality control during aging involves recruitment of the macroautophagy pathway by BAG3

    Martin Gamerdinger;Parvana Hajieva;A Murat Kaya;Uwe Wolfrum

  • The antioxidant neuroprotective effects of estrogens and phenolic compounds are independent from their estrogenic properties.

    Bernd Moosmann;Christian Behl

  • Amyloid peptides are toxic via a common oxidative mechanism

    D Schubert;C Behl;R Lesley;A Brack

  • Antioxidant neuroprotection in Alzheimer’s disease as preventive and therapeutic approach

    Christian Behl;Bernd Moosmann

  • Neuroprotective properties of cannabinoids against oxidative stress: role of the cannabinoid receptor CB1.

    Giovanni Marsicano;Bernd Moosmann;Heike Hermann;Beat Lutz

  • BAG3 mediates chaperone‐based aggresome‐targeting and selective autophagy of misfolded proteins

    Martin Gamerdinger;A Murat Kaya;Uwe Wolfrum;Albrecht M Clement

  • The Human DIMINUTO/DWARF1 Homolog Seladin-1 Confers Resistance to Alzheimer's Disease-Associated Neurodegeneration and Oxidative Stress

    Isabell Greeve;Irm Hermans-Borgmeyer;Claire Brellinger;Dagmar Kasper

  • Ubiquitin-independent function of optineurin in autophagic clearance of protein aggregates.

    Jelena Korac;Veronique Schaeffer;Igor Kovacevic;Albrecht M. Clement

Frequent Co-Authors

Florian Holsboer
Florian Holsboer Max Planck Institute of Psychiatry
Ulrich Bogdahn
Ulrich Bogdahn University of Regensburg
Sergio Lavandero
Sergio Lavandero University of Chile
Ivan Dikic
Ivan Dikic Goethe University Frankfurt
David Schubert
David Schubert Salk Institute for Biological Studies
Boris Zhivotovsky
Boris Zhivotovsky Karolinska Institute
Jochen Walter
Jochen Walter University of Bonn
Evelina Gatti
Evelina Gatti Aix-Marseille University
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center
Andrea Ballabio
Andrea Ballabio Baylor College of Medicine

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