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53
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11059
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16092
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1273

Overview

Willem van Schaik is affiliated with the University of Birmingham in the United Kingdom. Their research spans multiple areas within Biochemistry, Genetics and Molecular Biology, with a significant focus on Medicine. They have produced 115 publications within Biochemistry, Genetics and Molecular Biology and 53 within Medicine.

The scientist's subfields of study include Molecular Medicine, Molecular Biology, Endocrinology, Infectious Diseases, and Epidemiology. Their main research topics cover a variety of areas related to microbial and antibiotic resistance, such as Antibiotic Resistance in Bacteria, Gut Microbiota and Health, Bacterial Biofilms and Quorum Sensing, Antimicrobial Resistance in Staphylococcus, Antibiotics Pharmacokinetics and Efficacy, Pharmaceutical and Antibiotic Environmental Impacts, and Bacterial Identification and Susceptibility Testing.

Willem van Schaik has frequently published in venues such as bioRxiv (Cold Spring Harbor Laboratory), Microbial Genomics, Nature Communications, Microbiology Spectrum, and the Journal of Antimicrobial Chemotherapy. These reflect the scientist's concentration on microbiology and antimicrobial resistance fields.

Notable recent papers include:

  • Horizontal transfer of antibiotic resistance genes in the human gut microbiome, 2020, Current Opinion in Microbiology
  • Effects of early-life antibiotics on the developing infant gut microbiome and resistome: a randomized trial, 2022, Nature Communications
  • Plasmids Shaped the Recent Emergence of the Major Nosocomial Pathogen Enterococcus faecium, 2020, mBio
  • A Pilot Integrative Analysis of Colonic Gene Expression, Gut Microbiota, and Immune Infiltration in Primary Sclerosing Cholangitis-Inflammatory Bowel Disease: Association of Disease With Bile Acid Pathways, 2020, Journal of Crohn's and Colitis
  • Antibiotic resistance in the commensal human gut microbiota, 2022, Current Opinion in Microbiology

Collaborations constitute a significant part of van Schaik's work, with frequent coauthors including Robert A. Moran, Alan McNally, Xiaoting Hua, Yunsong Yu, and Ross S. McInnes. These collaborative efforts span dozens of joint publications, underscoring a networked approach to addressing challenging questions in microbial genomics and antimicrobial resistance.

Best Publications

  • Emergence of Epidemic Multidrug-Resistant Enterococcus faecium from Animal and Commensal Strains

    François Lebreton;François Lebreton;Willem van Schaik;Willem van Schaik;Willem van Schaik;Abigail Manson McGuire Manson McGuire;Paul Godfrey

  • Whole-Genome Sequencing of Bacterial Pathogens: the Future of Nosocomial Outbreak Analysis

    Scott Quainoo;Jordy P. M. Coolen;Sacha A. F. T. van Hijum;Martijn A. Huynen

  • Global Emergence and Dissemination of Enterococci as Nosocomial Pathogens : Attack of the Clones?

    Ana M. Guzman Prieto;Willem van Schaik;Malbert R. C. Rogers;Teresa M. Coque

  • Dissemination of Cephalosporin Resistance Genes between Escherichia coli Strains from Farm Animals and Humans by Specific Plasmid Lineages

    Mark de Been;Val F. Lanza;María de Toro;Jelle Scharringa

  • The human gut resistome

    Willem van Schaik

  • Core Genome Multilocus Sequence Typing Scheme for High-Resolution Typing of Enterococcus faecium

    Mark de Been;Mette Pinholt;Mette Pinholt;Janetta Top;Stefan Bletz

  • Genomic transition of enterococci from gut commensals to leading causes of multidrug-resistant hospital infection in the antibiotic era.

    Michael S. Gilmore;Francois Herve Lebreton;Willem van Schaik;Willem van Schaik

  • Horizontal transfer of antibiotic resistance genes in the human gut microbiome.

    Ross S McInnes;Gregory E McCallum;Lisa E Lamberte;Willem van Schaik

  • Pyrosequencing-based comparative genome analysis of the nosocomial pathogen Enterococcus faecium and identification of a large transferable pathogenicity island

    Willem van Schaik;Janetta Top;David R Riley;Jos Boekhorst

  • The role of sigmaB in the stress response of Gram-positive bacteria -- targets for food preservation and safety.

    Willem van Schaik;Tjakko Abee

  • On the (im)possibility of reconstructing plasmids from whole-genome short-read sequencing data.

    Sergio Arredondo-Alonso;Rob J. Willems;Willem van Schaik;Willem van Schaik;Anita C. Schürch

  • Restricted Gene Flow among Hospital Subpopulations of Enterococcus faecium

    Rob J L Willems;Janetta Top;Willem van Schaik;Helen Leavis

  • Antibiotic resistant enterococci-tales of a drug resistance gene trafficker.

    Guido Werner;Teresa M. Coque;Charles M.A.P. Franz;Elisabeth Grohmann

  • Transition of Enterococcus faecium from commensal organism to nosocomial pathogen.

    Rob Jl Willems;Willem van Schaik

  • Prediction of the intestinal resistome by a three-dimensional structure-based method.

    Etienne Ruppé;Etienne Ruppé;Amine Ghozlane;Amine Ghozlane;Julien Tap;Nicolas Pons

  • Identification of proteins involved in the heat stress response of Bacillus cereus ATCC 14579

    Paula M. Periago;Willem van Schaik;Tjakko Abee;Jeroen A. Wouters

  • Acid-adapted Listeria monocytogenes displays enhanced tolerance against the lantibiotics nisin and lacticin 3147.

    Willem van Schaik;Cormac G. M. Gahan;Colin Hill

  • LPxTG surface proteins of enterococci

    Antoni P.A. Hendrickx;Rob J.L. Willems;Marc J.M. Bonten;Willem van Schaik

  • In-depth resistome analysis by targeted metagenomics

    Val F. Lanza;Fernando Baquero;José Luís Martínez;Ricardo Ramos-Ruíz

  • Complement resistance mechanisms of Klebsiella pneumoniae

    Dennis J. Doorduijn;Suzan H.M. Rooijakkers;Willem van Schaik;Bart W. Bardoel

Frequent Co-Authors

Rob J. L. Willems
Rob J. L. Willems Utrecht University
Marc J. M. Bonten
Marc J. M. Bonten Utrecht University
Tjakko Abee
Tjakko Abee Wageningen University & Research
Teresa M. Coque
Teresa M. Coque Instituto Ramón y Cajal de Investigación Sanitaria
Janetta Top
Janetta Top Utrecht University
Willem M. de Vos
Willem M. de Vos Wageningen University & Research
Michael S. Gilmore
Michael S. Gilmore Harvard Medical School
Fernando Baquero
Fernando Baquero Instituto Ramón y Cajal de Investigación Sanitaria
Jukka Corander
Jukka Corander University of Oslo
Antoine Andremont
Antoine Andremont Université Paris Cité

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