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Biology and Biochemistry

D-Index
57
Citations
8411
World Ranking
14105
National Ranking
5949

Overview

Rosalia C. M. Simmen is affiliated with the University of Arkansas for Medical Sciences in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a notable emphasis on Molecular Biology as a subfield.

The scientist has contributed extensively to topics such as Metabolism, Diabetes, and Cancer, Kruppel-like factors research, Endometriosis Research and Treatment, Reproductive System and Pregnancy, Genomics, Phytochemicals, and Oxidative Stress, Endometrial and Cervical Cancer Treatments, and Growth Hormone and Insulin-like Growth Factors.

Frequent coauthors in their work include Iad Alhallak, Frank A. Simmen, Maria Theresa E. Montales, Charles M. Quick, and John Mark P. Pabona.

Rosalia Simmen's research has been published in several journals, with multiple contributions in the following venues:

  • Journal of Molecular Endocrinology
  • Cancers
  • Reproductive Sciences
  • Journal of the Endocrine Society
  • Endocrine Connections

Some of their recent published papers include:

  • Malic enzyme 1 (ME1) in the biology of cancer: it is not just intermediary metabolism, 2020, Journal of Molecular Endocrinology
  • Metformin Promotes Anti-tumor Biomarkers in Human Endometrial Cancer Cells, 2020, Reproductive Sciences
  • Malic Enzyme 1 (ME1) Promotes Adiposity and Hepatic Steatosis and Induces Circulating Insulin and Leptin in Obese Female Mice, 2023, International Journal of Molecular Sciences
  • Krüppel-like Factor 9 (KLF9) Suppresses Hepatocellular Carcinoma (HCC)-Promoting Oxidative Stress and Inflammation in Mice Fed High-Fat Diet, 2022, Cancers
  • Krüppel-like Factor-9 and Krüppel-like Factor-13: Highly Related, Multi-Functional, Transcriptional Repressors and Activators of Oncogenesis, 2023, Cancers

Best Publications

  • Association of a genetic marker with blood serum insulin-like growth factor-I concentration and growth traits in Angus cattle.

    W. Ge;M. E. Davis;H. C. Hines;K. M. Irvin

  • Porcine insulin-like growth factor-I (pIGF-I): complementary deoxyribonucleic acid cloning and uterine expression of messenger ribonucleic acid encoding evolutionarily conserved IGF-I peptides.

    Amir Tavakkol;Frank A. Simmen;Rosalia C. M. Simmen

  • Expression of messenger RNAs encoding insulin-like growth factor-I, -II, and insulin-like growth factor binding protein-2 in bovine endometrium during the estrous cycle and early pregnancy.

    Rodney D. Geisert;Chul-Young Lee;Frank A. Simmen;Michael T. Zavy

  • Association of single nucleotide polymorphisms in the growth hormone and growth hormone receptor genes with blood serum insulin-like growth factor I concentration and growth traits in Angus cattle.

    W. Ge;M. E. Davis;H. C. Hines;K. M. Irvin

  • Hormonal Regulation of Insulin-Like Growth Factor Gene Expression in Pig Uterus*

    Rosalia C. M. Simmen;Frank A. Simmen;Andrea Hofig;Steven J. Farmer

  • Repression of mammosphere formation of human breast cancer cells by soy isoflavone genistein and blueberry polyphenolic acids suggests diet-mediated targeting of cancer stem-like/progenitor cells

    Maria Theresa E. Montales;Omar M. Rahal;Jie Kang;Theodore J. Rogers

  • Differential expression, during the estrous cycle and pre- and postimplantation conceptus development, of messenger ribonucleic acids encoding components of the pig uterine insulin-like growth factor system.

    F A Simmen;R C Simmen;R D Geisert;F Martinat-Botte

  • Insulin-like growth factors in sheep uterine fluids: concentrations and relationship to ovine trophoblast protein-1 production during early pregnancy.

    Y. Ko;C. Y. Lee;T. L. Ott;M. A. Davis

  • Maternal and neonatal somatomedin C/insulin-like growth factor-I (IGF-I) and IGF binding proteins during early lactation in the pig.

    Frank A. Simmen;Rosalia C.M. Simmen;Gregory Reinhart

  • Selective Interactions of Krüppel-like Factor 9/Basic Transcription Element-binding Protein with Progesterone Receptor Isoforms A and B Determine Transcriptional Activity of Progesterone-responsive Genes in Endometrial Epithelial Cells

    Xue-Lian Zhang;Daying Zhang;Frank J. Michel;Jason L. Blum

  • Krüppel-Like Factor 9 and Progesterone Receptor Coregulation of Decidualizing Endometrial Stromal Cells: Implications for the Pathogenesis of Endometriosis

    John Mark P. Pabona;Frank A. Simmen;Mikhail A. Nikiforov;DaZhong Zhuang

  • Molecular cloning of the type 5, iron-containing, tartrate-resistant acid phosphatase from human placenta.

    C M Ketcham;R M Roberts;R C M Simmen;H S Nick

  • Genetic parameter estimates for serum insulin-like growth factor-I concentration and carcass traits in Angus beef cattle.

    M. E. Davis;R. C. M. Simmen

  • Soy protein isolate and protection against cancer.

    Thomas M Badger;Martin J J Ronis;Rosalia C M Simmen;Frank A Simmen

  • The soy isoflavone genistein promotes apoptosis in mammary epithelial cells by inducing the tumor suppressor PTEN

    Bhuvanesh Dave;Renea R. Eason;S.Renée Till;Yan Geng

  • Soy isoflavone genistein upregulates epithelial adhesion molecule E-cadherin expression and attenuates β-catenin signaling in mammary epithelial cells

    Ying Su;Rosalia C.M. Simmen

  • Insulin-like growth factor-I expression during early conceptus development in the pig.

    Roxanne Letcher;Rosalia C. M. Simmen;Fuller W. Bazer;Frank A. Simmen

  • Secretory Leukocyte Protease Inhibitor Mediates Proliferation of Human Endometrial Epithelial Cells by Positive and Negative Regulation of Growth-associated Genes

    Daying Zhang;Rosalia C.M. Simmen;Frank J. Michel;Ge Zhao

  • Subfertility, uterine hypoplasia, and partial progesterone resistance in mice lacking the Krüppel-like factor 9/basic transcription element-binding protein-1 (Bteb1) gene

    Rosalia C.M. Simmen;Renea R. Eason;Jennelle R. McQuown;Amanda L. Linz

  • Expression profiling of rat mammary epithelial cells reveals candidate signaling pathways in dietary protection from mammary tumors

    Ying Su;Frank A. Simmen;Rijin Xiao;Rosalia C. M. Simmen

Frequent Co-Authors

Michael E. Davis
Michael E. Davis The Ohio State University
Fuller W. Bazer
Fuller W. Bazer Texas A&M University
Thomas M. Badger
Thomas M. Badger University of Arkansas for Medical Sciences
K. Shankar
K. Shankar Saveetha University
Xianli Wu
Xianli Wu Agricultural Research Service
Anthony R. Means
Anthony R. Means Baylor College of Medicine
Ronald L. Prior
Ronald L. Prior United States Department of Agriculture
Stepan Melnyk
Stepan Melnyk University of Arkansas for Medical Sciences
Linda C. Giudice
Linda C. Giudice University of California, San Francisco
D. C. Mahan
D. C. Mahan The Ohio State University

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