Jinyi Xu

Overview

Best Publications

• The structural modification of natural products for novel drug discovery.

  Hong Yao;Junkai Liu;Shengtao Xu;Zheying Zhu

  268
  Citations

• Multi-target design strategies for the improved treatment of Alzheimer's disease

  Pengfei Zhang;Shengtao Xu;Zheying Zhu;Jinyi Xu

  224
  Citations

• Efficient Iron-Catalyzed N-Arylation of Aryl Halides with Amines

  Diliang Guo;He Huang;Jinyi Xu;Hualiang Jiang

  174
  Citations

• Insights into drug discovery from natural products through structural modification.

  Jichao Chen;Wenlong Li;Hequan Yao;Jinyi Xu

  164
  Citations

• Efficient Construction of Fused Indolines with a 2-Quaternary Center via an Intramolecular Heck Reaction with a Low Catalyst Loading

  Lei Zhao;Ziyuan Li;Lin Chang;Jinyi Xu

  163
  Citations

• Synthesis of spiro[2.5]octa-4,7-dien-6-one with consecutive quaternary centers via 1,6-conjugate addition induced dearomatization of para-quinone methides

  Kuo Gai;Xinxin Fang;Xuanyi Li;Jinyi Xu

  160
  Citations

• Tubulin inhibitors targeting the colchicine binding site: a perspective of privileged structures

  Wenlong Li;Honghao Sun;Shengtao Xu;Zheying Zhu

  150
  Citations

• A pharmacological probe identifies cystathionine β-synthase as a new negative regulator for ferroptosis.

  Li Wang;Hao Cai;Youtian Hu;Fan Liu

  137
  Citations

• Development of Inhibitors of the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Signaling Pathway.

  Tianyu Wang;Xiaoxing Wu;Changying Guo;Kuojun Zhang

  126
  Citations

• Discovery of Novel Quinoline–Chalcone Derivatives as Potent Antitumor Agents with Microtubule Polymerization Inhibitory Activity

  Wenlong Li;Feijie Xu;Wen Shuai;Honghao Sun

  123
  Citations

• Solvent-Controlled Switchable C–H Alkenylation of 4-Aryl-1H-pyrrole-3-carboxylates: Application to the Total Synthesis of (±)-Rhazinilam

  Youla Su;Haipin Zhou;Jiaxuan Chen;Jinyi Xu

  122
  Citations

• A Novel Potent Anticancer Compound Optimized from a Natural Oridonin Scaffold Induces Apoptosis and Cell Cycle Arrest through the Mitochondrial Pathway

  Shengtao Xu;Hong Yao;Shanshan Luo;Yun-Kai Zhang

  108
  Citations

• Multiple Roles of the Pyrimidyl Group in the Rhodium-Catalyzed Regioselective Synthesis and Functionalization of Indole-3-carboxylic Acid Esters

  Hui Jiang;Shang Gao;Jinyi Xu;Xiaoming Wu

  106
  Citations

• Ligand-free iron/copper cocatalyzed N-arylations of aryl halides with amines under microwave irradiation

  Diliang Guo;Diliang Guo;He Huang;Yu Zhou;Jinyi Xu

  98
  Citations

• Pd(II)-catalyzed direct C5-arylation of azole-4-carboxylates through double C–H bond cleavage

  Ziyuan Li;Ling Ma;Jinyi Xu;Lingyi Kong

  96
  Citations

• The conversion of oridonin to spirolactone-type or enmein-type diterpenoid: synthesis and biological evaluation of ent-6,7-seco-oridonin derivatives as novel potential anticancer agents.

  Lei Wang;Dahong Li;Shengtao Xu;Hao Cai

  88
  Citations

• Copper-catalyzed C5-selective thio/selenocyanation of 8-aminoquinolines

  Jichao Chen;Tianyu Wang;Tong Wang;Tong Wang;Aijun Lin

  86
  Citations

• A Mannich/cyclization cascade process for the asymmetric synthesis of spirocyclic thioimidazolidineoxindoles

  Hao Cai;Hao Cai;Yu Zhou;Dong Zhang;Dong Zhang;Jinyi Xu

  84
  Citations

• Cell-Permeable Iminocoumarine-Based Fluorescent Dyes for Mitochondria

  Diliang Guo;Tao Chen;Deju Ye;Jinyi Xu

  82
  Citations

• Design, synthesis and biological evaluation of quinoline-indole derivatives as anti-tubulin agents targeting the colchicine binding site.

  Wenlong Li;Wen Shuai;Honghao Sun;Feijie Xu

  80
  Citations

• Synthesis and biological evaluation of novel 1-O- and 14-O-derivatives of oridonin as potential anticancer drug candidates.

  Jinyi Xu;JingYi Yang;Qian Ran;Lei Wang

  74
  Citations