World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
73
Citations
16033
World Ranking
6049
National Ranking
190

Overview

Qinglong Guo is affiliated with China Pharmaceutical University in China and focuses on research primarily in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans multiple subfields including Molecular Biology, Epidemiology, Cell Biology, Pharmacology, and Immunology.

The scientist's research explores various topics such as:

  • Autophagy in Disease and Therapy
  • Flavonoids in Medical Research
  • Aldose Reductase and Taurine
  • Histone Deacetylase Inhibitors Research
  • Tuberculosis Research and Epidemiology
  • Ubiquitin and proteasome pathways
  • Calcium signaling and nucleotide metabolism

Qinglong Guo has contributed to multiple frequent publication venues, including:

  • Blood
  • Journal of Medicinal Chemistry
  • Acta Pharmacologica Sinica
  • Research Square
  • Oncogene

Recent notable papers featuring Qinglong Guo's research include:

  • CDK9 inhibition blocks the initiation of PINK1-PRKN-mediated mitophagy by regulating the SIRT1-FOXO3-BNIP3 axis and enhances the therapeutic effects involving mitochondrial dysfunction in hepatocellular carcinoma, published in 2021 in Autophagy
  • Overview of AKR1C3: Inhibitor Achievements and Disease Insights, published in 2020 in Journal of Medicinal Chemistry
  • Oroxylin A reverses hypoxia-induced cisplatin resistance through inhibiting HIF-1α mediated XPC transcription, published in 2020 in Oncogene
  • Wogonin induces cellular senescence in breast cancer via suppressing TXNRD2 expression, published in 2020 in Archives of Toxicology
  • FV-429 induces autophagy blockage and lysosome-dependent cell death of T-cell malignancies via lysosomal dysregulation, published in 2021 in Cell Death and Disease

Among frequent co-authors, Qinglong Guo has collaborated most extensively with Hui Hui (17 publications), Li Zhao (13 publications), Libin Wei (10 publications), Po Hu (10 publications), and Hui Li (10 publications).

Best Publications

  • HIF-1α is critical for hypoxia-mediated maintenance of glioblastoma stem cells by activating Notch signaling pathway

    Qiang L;Wu T;Zhang Hw;Lu N

  • Endostar, a novel recombinant human endostatin, exerts antiangiogenic effect via blocking VEGF-induced tyrosine phosphorylation of KDR/Flk-1 of endothelial cells.

    Yun Ling;Yong Yang;Na Lu;Qi-dong You

  • ISOLATION AND CHARACTERIZATION OF CANCER STEM LIKE CELLS IN HUMAN GLIOBLASTOMA CELL LINES

    Lei Qiang;Yong Yang;Yan-Jun Ma;Fei-Hong Chen

  • Gambogic acid-induced G2/M phase cell-cycle arrest via disturbing CDK7-mediated phosphorylation of CDC2/p34 in human gastric carcinoma BGC-823 cells.

    Jun Yu;Qing-Long Guo;Qi-Dong You;Li Zhao

  • Gambogic acid inhibits proliferation of human lung carcinoma SPC-A1 cells in vivo and in vitro and represses telomerase activity and telomerase reverse transcriptase mRNA expression in the cells.

    Zhao-Qiu Wu;Qing-Long Guo;Qi-Dong You;Li Zhao

  • Anti-hepatitis B virus activity of wogonin in vitro and in vivo.

    Qinglong Guo;Li Zhao;Qidong You;Yong Yang

  • Flavonoid baicalein suppresses adhesion, migration and invasion of MDA-MB-231 human breast cancer cells

    Ling Wang;Yun Ling;Yan Chen;Cheng-Ling Li

  • Differential apoptotic induction of gambogic acid, a novel anticancer natural product, on hepatoma cells and normal hepatocytes.

    Yong Yang;Lan Yang;Qi-Dong You;Fei-Fei Nie

  • Oroxylin A induces dissociation of hexokinase II from the mitochondria and inhibits glycolysis by SIRT3-mediated deacetylation of cyclophilin D in breast carcinoma

    Wei L;Zhou Y;Dai Q;Qiao C

  • Inhibition of human telomerase reverse transcriptase gene expression by gambogic acid in human hepatoma SMMC-7721 cells

    Qing-Long Guo;Sen-Sen Lin;Qi-Dong You;Hong-Yan Gu

  • Curcumol induces RIPK1/RIPK3 complex-dependent necroptosis via JNK1/2-ROS signaling in hepatic stellate cells.

    Yan Jia;Feixia Wang;Qin Guo;Mengmeng Li

  • Wogonoside protects against dextran sulfate sodium-induced experimental colitis in mice by inhibiting NF-κB and NLRP3 inflammasome activation

    Yang Sun;Yue Zhao;Jing Yao;Li Zhao

  • Inhibitory Effects of Baicalein on the Influenza Virus in Vivo Is Determined by Baicalin in the Serum

    Ge Xu;Jie Dou;Lei Zhang;Qinglong Guo

  • Gambogic acid inhibits angiogenesis through suppressing vascular endothelial growth factor-induced tyrosine phosphorylation of KDR/Flk-1.

    Na Lu;Yong Yang;Qi-Dong You;Yun Ling

  • Drug resistance associates with activation of Nrf2 in MCF-7/DOX cells, and wogonin reverses it by down-regulating Nrf2-mediated cellular defense response.

    Yan Zhong;Fengyi Zhang;Zhongying Sun;Wei Zhou

  • Apoptosis induction of oroxylin A in human cervical cancer HeLa cell line in vitro and in vivo

    Hua-Nan Li;Fei-Fei Nie;Wei Liu;Qin-Sheng Dai

  • NF-κB and Nrf2 signaling pathways contribute to wogonin-mediated inhibition of inflammation-associated colorectal carcinogenesis

    Yao J;Zhao L;Zhao Q;Zhao Y

  • Wogonoside induces cell cycle arrest and differentiation by affecting expression and subcellular localization of PLSCR1 in AML cells.

    Yan Chen;Hui Hui;Hao Yang;Kai Zhao

  • Wogonin induced G1 cell cycle arrest by regulating Wnt/β-catenin signaling pathway and inactivating CDK8 in human colorectal cancer carcinoma cells.

    Licheng He;Na Lu;Qinsheng Dai;Yue Zhao

  • Wogonin reverses hypoxia resistance of human colon cancer HCT116 cells via downregulation of HIF-1α and glycolysis, by inhibiting PI3K/Akt signaling pathway.

    Hu Wang;Li Zhao;Li-Tao Zhu;Yu Wang

Frequent Co-Authors

Na Lu
Na Lu China Pharmaceutical University
Qidong You
Qidong You China Pharmaceutical University
Ling-Yi Kong
Ling-Yi Kong China Pharmaceutical University
Yang Sun
Yang Sun Nanjing University
Stephen J. Weiss
Stephen J. Weiss University of Michigan–Ann Arbor
Ronald M. Evans
Ronald M. Evans Salk Institute for Biological Studies
Hequan Yao
Hequan Yao China Pharmaceutical University
Jinyi Xu
Jinyi Xu China Pharmaceutical University
Bernd Schnabl
Bernd Schnabl University of California, San Diego
Feng Wang
Feng Wang Nanjing Agricultural University

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