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Biology and Biochemistry

D-Index
95
Citations
41758
World Ranking
1877
National Ranking
1032

Overview

Stephen J. Weiss is affiliated with the University of Michigan-Ann Arbor in the United States. Their research spans several aspects of biochemistry, genetics, molecular biology, and medicine, contributing to a comprehensive body of work across these fields.

The scientist's primary areas of study include molecular biology, oncology, cell biology, cancer research, and hematology. These subfields support their focus on specific scientific topics such as protease and inhibitor mechanisms, bone health and treatments, multiple myeloma research and treatments, bone metabolism and diseases, cellular mechanics and interactions, heterotopic ossification and related conditions, and bone and dental protein studies.

They have published research in multiple journals, with frequent contributions to the following publication venues:

  • Blood
  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • Journal of Clinical Investigation
  • Nature Communications
  • The Journal of Cell Biology

Recent papers authored or co-authored by Stephen J. Weiss include:

  • Osteoclast-mediated bone resorption is controlled by a compensatory network of secreted and membrane-tethered metalloproteinases, 2020, Science Translational Medicine
  • Immobilization after injury alters extracellular matrix and stem cell fate, 2020, Journal of Clinical Investigation
  • Inactivation of endothelial ZEB1 impedes tumor progression and sensitizes tumors to conventional therapies, 2020, Journal of Clinical Investigation
  • Divergent regulation of basement membrane trafficking by human macrophages and cancer cells, 2022, Nature Communications
  • SLIT3 deficiency attenuates pressure overload-induced cardiac fibrosis and remodeling, 2020, JCI Insight

Stephen J. Weiss has frequently collaborated with a group of co-authors, including:

  • Yi Tang
  • Lingxin Zhu
  • Jung-Sun Cho
  • Huihui Ma
  • Gabriel M. Pagnotti

Best Publications

  • Tissue Destruction by Neutrophils

    Stephen J. Weiss

  • EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells

    Celina G. Kleer;Qi Cao;Sooryanarayana Varambally;Ronglai Shen

  • Physical limits of cell migration: Control by ECM space and nuclear deformation and tuning by proteolysis and traction force

    Katarina Wolf;Mariska te Lindert;Marina Krause;Stephanie Alexander

  • Regulation of transendothelial neutrophil migration by endogenous interleukin-8

    Andreas R. Huber;Steven L. Kunkel;Robert F. Todd;Stephen J. Weiss

  • Chlorination of taurine by human neutrophils. Evidence for hypochlorous acid generation.

    Stephen J. Weiss;Roger Klein;Adam Slivka;Maria Wei

  • MATRIX METALLOPROTEINASES REGULATE NEOVASCULARIZATION BY ACTING AS PERICELLULAR FIBRINOLYSINS

    Nobuaki Hiraoka;Edward Allen;Ingrid J Apel;Margaret R Gyetko

  • Membrane type I matrix metalloproteinase usurps tumor growth control imposed by the three-dimensional extracellular matrix

    Kevin B Hotary;Edward D Allen;Peter C Brooks;Nabanita S Datta

  • Furin-dependent intracellular activation of the human stromelysin-3 zymogen

    Duanqing Pei;Stephen J. Weiss

  • Protease-dependent versus -independent cancer cell invasion programs: three-dimensional amoeboid movement revisited

    Farideh Sabeh;Ryoko Shimizu-Hirota;Stephen J. Weiss

  • Regulation of Cell Invasion and Morphogenesis in a Three-Dimensional Type I Collagen Matrix by Membrane-Type Matrix Metalloproteinases 1, 2, and 3

    Kevin Hotary;Edward Allen;Antonello Punturieri;Ikuo Yana

  • A Wnt-Axin2-GSK3beta cascade regulates Snail1 activity in breast cancer cells.

    Jong In Yook;Xiao Yan Li;Ichiro Ota;Casey Hu

  • Role of hydrogen peroxide in neutrophil-mediated destruction of cultured endothelial cells.

    Stephen J. Weiss;Judy Young;Albert F. Lobuglio;Adam Slivka

  • Snail1-induced partial epithelial-to-mesenchymal transition drives renal fibrosis in mice and can be targeted to reverse established disease

    M Teresa Grande;Berta Sánchez-Laorden;Cristina López-Blau;Cristina A De Frutos

  • Tumor Cell Traffic through the Extracellular Matrix Is Controlled by the Membrane-anchored Collagenase MT1-MMP

    Farideh Sabeh;Ichiro Ota;Kenn Holmbeck;Henning Birkedal-Hansen

  • Oxidative Autoactivation of Latent Collagenase by Human Neutrophils

    S. J. Weiss;G. Peppin;X. Ortiz;C. Ragsdale

  • Breaching the basement membrane: who, when and how?

    R. Grant Rowe;Stephen J. Weiss

  • Phagocyte-generated oxygen metabolites and cellular injury

    Weiss Sj;LoBuglio Af

  • Wnt-dependent Regulation of the E-cadherin Repressor Snail

    Jong In Yook;Xiao-Yan Li;Ichiro Ota;Eric R. Fearon

  • Long-lived oxidants generated by human neutrophils: characterization and bioactivity

    S. J. Weiss;M. B. Lampert;S. T. Test

  • Transmembrane-deletion Mutants of the Membrane-type Matrix Metalloproteinase-1 Process Progelatinase A and Express Intrinsic Matrix-degrading Activity

    Duanqing Pei;Stephen J. Weiss

Frequent Co-Authors

Henning Birkedal-Hansen
Henning Birkedal-Hansen National Institutes of Health
Albert F. LoBuglio
Albert F. LoBuglio University of Alabama at Birmingham
Thomas L. Saunders
Thomas L. Saunders University of Michigan–Ann Arbor
Eric R. Fearon
Eric R. Fearon University of Michigan–Ann Arbor
Duanqing Pei
Duanqing Pei Westlake University
Celina G. Kleer
Celina G. Kleer University of Michigan–Ann Arbor
James Varani
James Varani University of Michigan–Ann Arbor
Harold A. Chapman
Harold A. Chapman University of California, San Francisco
Gregg B. Fields
Gregg B. Fields Florida Atlantic University
Kent J. Johnson
Kent J. Johnson University of Michigan–Ann Arbor

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