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Biology and Biochemistry

D-Index
68
Citations
18279
World Ranking
7729
National Ranking
599

Overview

Yoshifumi Itoh is a researcher affiliated with the University of Oxford in the United Kingdom, focusing primarily on Medicine and Biochemistry, Genetics and Molecular Biology. Their scholarly contributions span several key areas including Cancer Research, Oncology, Molecular Biology, Cell Biology, and Immunology and Allergy.

Their main research topics include:

  • Protease and Inhibitor Mechanisms
  • Peptidase Inhibition and Analysis
  • Cell Adhesion Molecules Research
  • Bone Metabolism and Diseases
  • Proteoglycans and Glycosaminoglycans Research
  • Immune Response and Inflammation
  • Neurogenesis and Neuroplasticity Mechanisms

Yoshifumi Itoh has authored several recent papers, notable among them:

  • "Proteolytic modulation of tumor microenvironment signals during cancer progression" (2022), published in Frontiers in Oncology
  • "Roles of Toll-like Receptor Signaling in Inflammatory Bone Resorption" (2024), published in Biology
  • "Alpha-2-Macroglobulin in Inflammation, Immunity and Infections" (2021), published in Frontiers in Immunology
  • "Gram-positive bacteria cell wall-derived lipoteichoic acid induces inflammatory alveolar bone loss through prostaglandin E production in osteoblasts" (2021), published in Scientific Reports
  • "Autofluorescence Lifetime Reports Cartilage Damage in Osteoarthritis" (2020), published in Scientific Reports

Frequent co-authors in their body of work include:

  • Masaki Inada
  • Tsukasa Tominari
  • Michiko Hirata
  • Michael L. Dustin
  • Chiho Matsumoto

Yoshifumi Itoh commonly publishes in the following venues:

  • American Journal Of Pathology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Biochemical and Biophysical Research Communications
  • Scientific Reports
  • Matrix Biology

Best Publications

  • Membrane-Type 1 Matrix Metalloproteinase Cleaves Cd44 and Promotes Cell Migration

    Masahiro Kajita;Yoshifumi Itoh;Tadashige Chiba;Hidetoshi Mori

  • The membrane-anchored MMP inhibitor RECK is a key regulator of extracellular matrix integrity and angiogenesis.

    Junseo Oh;Rei Takahashi;Shunya Kondo;Akira Mizoguchi

  • Purification and cloning of aggrecanase-1: a member of the ADAMTS family of proteins.

    M. D. Tortorella;T. C. Burn;M. A. Pratta;I. Abbaszade

  • Cloning and characterization of ADAMTS11, an aggrecanase from the ADAMTS family.

    Ilgar Abbaszade;Rui-Qin Liu;Fude Yang;Stuart A. Rosenfeld

  • MT1-MMP: a potent modifier of pericellular microenvironment.

    Yoshifumi Itoh;Motoharu Seiki

  • Degradation of interleukin 1beta by matrix metalloproteinases.

    Akira Ito;Akihira Mukaiyama;Yoshifumi Itoh;Hideaki Nagase

  • Homophilic complex formation of MT1-MMP facilitates proMMP-2 activation on the cell surface and promotes tumor cell invasion.

    Yoshifumi Itoh;Akiko Takamura;Noriko Ito;Yoshiro Maru

  • Small, stable shuttle vectors based on the minimal pVS1 replicon for use in gram-negative, plant-associated bacteria.

    Stephan Heeb;Yoshifumi Itoh;Takayuki Nishijyo;Ursula Schnider

  • Membrane-type matrix metalloproteinases: Their functions and regulations.

    Yoshifumi Itoh

  • CD44 directs membrane‐type 1 matrix metalloproteinase to lamellipodia by associating with its hemopexin‐like domain

    Hidetoshi Mori;Taizo Tomari;Naohiko Koshikawa;Masahiro Kajita

  • Matrix metalloproteinases in cancer.

    Yoshifumi Itoh;Hideaki Nagase

  • Proteoglycans in health and disease: the multiple roles of syndecan shedding.

    Tina Manon‐Jensen;Yoshifumi Itoh;John R. Couchman

  • Characterization of the interface between normal and transformed epithelial cells.

    Catherine Hogan;Sophie Dupré-Crochet;Sophie Dupré-Crochet;Mark Norman;Mihoko Kajita

  • Cytoplasmic tail-dependent internalization of membrane-type 1 matrix metalloproteinase is important for its invasion-promoting activity.

    Takamasa Uekita;Yoshifumi Itoh;Ikuo Yana;Hiroshi Ohno

  • Matrix Metalloproteinase-2 Production and Its Binding to the Matrix Are Increased in Abdominal Aortic Aneurysms

    V Davis;R Persidskaia;L Baca-Regen;Y Itoh

  • Claudin Promotes Activation of Pro-matrix Metalloproteinase-2 Mediated by Membrane-type Matrix Metalloproteinases

    Hisashi Miyamori;Takahisa Takino;Yuko Kobayashi;Hideaki Tokai

  • The CbrA–CbrB two-component regulatory system controls the utilization of multiple carbon and nitrogen sources in Pseudomonas aeruginosa

    Takayuki Nishijyo;Dieter Haas;Yoshifumi Itoh

  • Steps Involved in Activation of the Pro-matrix Metalloproteinase 9 (Progelatinase B)-Tissue Inhibitor of Metalloproteinases-1 Complex by 4-Aminophenylmercuric Acetate and Proteinases

    Yutaka Ogata;Yoshifumi Itoh;Hideaki Nagase

  • Altered proteolytic activities of ADAMTS-4 expressed by C-terminal processing

    Masahide Kashiwagi;Jan J. Enghild;Christi Gendron;Clare Hughes

  • Preferential Inactivation of Tissue Inhibitor of Metalloproteinases-1 That Is Bound to the Precursor of Matrix Metalloproteinase 9 (Progelatinase B) by Human Neutrophil Elastase

    Yoshifumi Itoh;Hideaki Nagase

Frequent Co-Authors

Hideaki Nagase
Hideaki Nagase University of Oxford
Motoharu Seiki
Motoharu Seiki University of Tokyo
Jan J. Enghild
Jan J. Enghild Aarhus University
Gillian Murphy
Gillian Murphy University of Cambridge
Yasunori Okada
Yasunori Okada Juntendo University
Bruce Caterson
Bruce Caterson Cardiff University
Naohiko Koshikawa
Naohiko Koshikawa Tokyo Institute of Technology
John R. Couchman
John R. Couchman University of Copenhagen
Hiroshi Sato
Hiroshi Sato Kanazawa University
Clare Elizabeth Hughes
Clare Elizabeth Hughes Cardiff University

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