Hiroshi Sato mostly deals with Molecular biology, Matrix metalloproteinase, Gelatinase A, Cell biology and Biochemistry. Hiroshi Sato has researched Molecular biology in several fields, including Cell culture, Gene expression, Northern blot, C-terminus and Expression vector. The concepts of his Matrix metalloproteinase study are interwoven with issues in Cell, Zymogen, Membrane, Activator and Extracellular matrix.
His study in Gelatinase A is interdisciplinary in nature, drawing from both Concanavalin A, Messenger RNA, Gelatinase and Pathology. His Cell biology research includes themes of Transfection, Cell membrane, Metalloproteinase, Cytotoxic T cell and Lymphokine-activated killer cell. As a part of the same scientific study, Hiroshi Sato usually deals with the Biochemistry, concentrating on Type I collagen and frequently concerns with Bone remodeling, Bone resorption, Osteoclast and Matrix metalloproteinase inhibitor.
Hiroshi Sato mainly investigates Molecular biology, Matrix metalloproteinase, Internal medicine, Pathology and Cell culture. His Molecular biology research is multidisciplinary, incorporating elements of Gene expression, Transcription factor, Transfection, Northern blot and Gene. His Matrix metalloproteinase study incorporates themes from Cell and Extracellular matrix, Cell biology.
Hiroshi Sato has included themes like Gastroenterology and Endocrinology in his Internal medicine study. The concepts of his Pathology study are interwoven with issues in Metastasis and In situ hybridization. His Cell culture research includes elements of Virus, Virology and In vitro.
Internal medicine, Gastroenterology, Surgery, Cancer research and Pathology are his primary areas of study. His research investigates the link between Internal medicine and topics such as Endocrinology that cross with problems in Cell culture, Signal transduction, Zymography and Proinflammatory cytokine. His Pathology research integrates issues from Stenosis and Primary biliary cirrhosis.
Hiroshi Sato works mostly in the field of Cell growth, limiting it down to topics relating to Glioma and, in certain cases, Molecular biology. His Molecular biology study combines topics in areas such as HEK 293 cells, Akt/PKB signaling pathway and Transfection. His study looks at the intersection of Carcinoma and topics like Metastasis with Matrix metalloproteinase.
His primary areas of investigation include Cancer research, Internal medicine, Gastroenterology, MMP9 and Gene knockdown. His Cancer research study integrates concerns from other disciplines, such as Tumor necrosis factor alpha, Cell growth, Cytokine, Molecular biology and Gene silencing. He interconnects v-Src, Gene expression and Proto-oncogene tyrosine-protein kinase Src in the investigation of issues within Molecular biology.
His MMP9 study is associated with Biochemistry. His research in Transfection focuses on subjects like HT1080, which are connected to Cell biology and Receptor. Hiroshi Sato combines subjects such as microRNA and Matrix metalloproteinase with his study of Small interfering RNA.
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CD1d-restricted and TCR-mediated activation of valpha14 NKT cells by glycosylceramides.
Tetsu Kawano;Junqing Cui;Yasuhiko Koezuka;Isao Toura.
Science (1997)
A matrix metalloproteinase expressed on the surface of invasive tumour cells
Hiroshi Sato;Takahisa Takino;Yasunori Okada;Jian Cao.
Nature (1994)
Membrane Type 1 Matrix Metalloproteinase Digests Interstitial Collagens and Other Extracellular Matrix Macromolecules
Eiko Ohuchi;Kazushi Imai;Yutaka Fujii;Hiroshi Sato.
Journal of Biological Chemistry (1997)
Regulatory mechanism of 92 kDa type IV collagenase gene expression which is associated with invasiveness of tumor cells
H Sato;M Seiki.
Oncogene (1993)
Identification of the second membrane-type matrix metalloproteinase (MT-MMP-2) gene from a human placenta cDNA library. MT-MMPs form a unique membrane-type subclass in the MMP family.
Takahisa Takino;Hiroshi Sato;Akira Shinagawa;Motoharu Seiki.
Journal of Biological Chemistry (1995)
Natural killer-like nonspecific tumor cell lysis mediated by specific ligand-activated Vα14 NKT cells
Tetsu Kawano;Junqing Cui;Yasuhiko Koezuka;Isao Toura.
Proceedings of the National Academy of Sciences of the United States of America (1998)
Transmembrane/cytoplasmic domain-mediated membrane type 1-matrix metalloprotease docking to invadopodia is required for cell invasion
Hirokazu Nakahara;Linda Howard;Erik W. Thompson;Hiroshi Sato.
Proceedings of the National Academy of Sciences of the United States of America (1997)
Stimulation of 92-kDa gelatinase B promoter activity by ras is mitogen-activated protein kinase kinase 1-independent and requires multiple transcription factor binding sites including closely spaced PEA3/ets and AP-1 sequences.
Rebecca Gum;Ernst Lengyel;Jose Juarez;Ji Hshiung Chen.
Journal of Biological Chemistry (1996)
Homophilic complex formation of MT1-MMP facilitates proMMP-2 activation on the cell surface and promotes tumor cell invasion.
Yoshifumi Itoh;Akiko Takamura;Noriko Ito;Yoshiro Maru.
The EMBO Journal (2001)
Activation of a recombinant membrane type 1-matrix metalloproteinase (MT1-MMP) by furin and its interaction with tissue inhibitor of metalloproteinases (TIMP)-2
Hiroshi Sato;Takeshi Kinoshita;Takahisa Takino;Kazuo Nakayama.
FEBS Letters (1996)
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