Hiroshi Sato

Overview

Best Publications

• A matrix metalloproteinase expressed on the surface of invasive tumour cells

  Hiroshi Sato;Takahisa Takino;Yasunori Okada;Jian Cao

  3256
  Citations

• Membrane Type 1 Matrix Metalloproteinase Digests Interstitial Collagens and Other Extracellular Matrix Macromolecules

  Eiko Ohuchi;Kazushi Imai;Yutaka Fujii;Hiroshi Sato

  1173
  Citations

• Regulatory mechanism of 92 kDa type IV collagenase gene expression which is associated with invasiveness of tumor cells

  H Sato;M Seiki

  887
  Citations

• Natural killer-like nonspecific tumor cell lysis mediated by specific ligand-activated Vα14 NKT cells

  Tetsu Kawano;Junqing Cui;Yasuhiko Koezuka;Isao Toura

  726
  Citations

• Identification of the second membrane-type matrix metalloproteinase (MT-MMP-2) gene from a human placenta cDNA library. MT-MMPs form a unique membrane-type subclass in the MMP family.

  Takahisa Takino;Hiroshi Sato;Akira Shinagawa;Motoharu Seiki

  712
  Citations

• Transmembrane/cytoplasmic domain-mediated membrane type 1-matrix metalloprotease docking to invadopodia is required for cell invasion

  Hirokazu Nakahara;Linda Howard;Erik W. Thompson;Hiroshi Sato

  546
  Citations

• Stimulation of 92-kDa gelatinase B promoter activity by ras is mitogen-activated protein kinase kinase 1-independent and requires multiple transcription factor binding sites including closely spaced PEA3/ets and AP-1 sequences.

  Rebecca Gum;Ernst Lengyel;Jose Juarez;Ji Hshiung Chen

  531
  Citations

• Homophilic complex formation of MT1-MMP facilitates proMMP-2 activation on the cell surface and promotes tumor cell invasion.

  Yoshifumi Itoh;Akiko Takamura;Noriko Ito;Yoshiro Maru

  503
  Citations

• Activation of a recombinant membrane type 1-matrix metalloproteinase (MT1-MMP) by furin and its interaction with tissue inhibitor of metalloproteinases (TIMP)-2

  Hiroshi Sato;Takeshi Kinoshita;Takahisa Takino;Kazuo Nakayama

  467
  Citations

• Localization of matrix metalloproteinase 9 (92-kilodalton gelatinase/type IV collagenase = gelatinase B) in osteoclasts: implications for bone resorption.

  Y. Okada;K. Naka;K. Kawamura;T. Matsumoto

  429
  Citations

• Expression of Membrane-Type Matrix Metalloproteinase in Human Gastric Carcinomas

  Hidehiro Nomura;Hiroshi Sato;Motoharu Seiki;Masayoshi Mai

  423
  Citations

• v-Src activates the expression of 92-kDa type IV collagenase gene through the AP-1 site and the GT box homologous to retinoblastoma control elements. A mechanism regulating gene expression independent of that by inflammatory cytokines.

  H Sato;M Kita;M Seiki

  414
  Citations

• TIMP-2 PROMOTES ACTIVATION OF PROGELATINASE A BY MEMBRANE-TYPE 1 MATRIX METALLOPROTEINASE IMMOBILIZED ON AGAROSE BEADS

  Takeshi Kinoshita;Hiroshi Sato;Akiko Okada;Eiko Ohuchi

  399
  Citations

• The C-terminal Region of Membrane Type Matrix Metalloproteinase Is a Functional Transmembrane Domain Required for Pro-gelatinase A Activation

  Jian Cao;Hiroshi Sato;Takahisa Takino;Motoharu Seiki

  388
  Citations

• Activation of the precursor of gelatinase A/72 kda type IV collagenase/MMP-2 in lung carcinomas correlates with the expression of membrane-type matrix metalloproteinase (MT-MMP) and with lymph node metastasis

  Masato Tokuraku;Hiroshi Sato;Sinya Murakami;Yasunori Okada

  380
  Citations

• Differential Expression of Membrane-Type Matrix Metalloproteinase and Its Correlation with Gelatinase A Activation in Human Malignant Brain Tumors in Vivo and in Vitro

  Masaaki Yamamoto;Sanjeeva Mohanam;Raymond Sawaya;Gregory N. Fuller

  366
  Citations

• Intermolecular Autolytic Cleavage Can Contribute to the Activation of Progelatinase A by Cell Membranes

  Susan J. Atkinson;Thomas Crabbe;Susan Cowell;Robin V. Ward

  345
  Citations

• Membrane-Type Matrix Metalloproteinase 1 Is a Gelatinolytic Enzyme and Is Secreted in a Complex with Tissue Inhibitor of Metalloproteinases 2

  Kazushi Imai;Eiko Ohuchi;Takanori Aoki;Hidehiro Nomura

  330
  Citations

• The expression of matrix metalloproteinase 9 is enhanced by Epstein–Barr virus latent membrane protein 1

  Tomokazu Yoshizaki;Hiroshi Sato;Mitsuru Furukawa;Joseph S. Pagano

  329
  Citations

• Expression and Tissue Localization of Membrane-Type 1, 2, and 3 Matrix Metalloproteinases in Human Astrocytic Tumors

  Mitsutoshi Nakada;Hiroyuki Nakamura;Eiji Ikeda;Noboru Fujimoto

  326
  Citations