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Takashi Ito

Takashi Ito

D-Index & Metrics

Genetics

D-Index
71
Citations
23335
World Ranking
2165
National Ranking
83

Overview

Takashi Ito is a researcher affiliated with Kyushu University in Japan. Their work spans the fields of Biochemistry, Genetics, and Molecular Biology, with significant contributions in Medicine. Their subfields of study include Molecular Biology, Cancer Research, Immunology, Genetics, and Surgery.

Their research topics focus on areas such as:

  • Epigenetics and DNA Methylation
  • RNA modifications and cancer
  • Cancer-related gene regulation
  • CRISPR and Genetic Engineering
  • Cancer Genomics and Diagnostics
  • RNA and protein synthesis mechanisms
  • Cancer, Hypoxia, and Metabolism

Ito has published frequently in several venues, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nucleic Acids Research
  • Scientific Reports
  • Research Square (Research Square)
  • Nature Communications

Recent papers connected with Takashi Ito include:

  • "NSD1-deposited H3K36me2 directs de novo methylation in the mouse male germline and counteracts Polycomb-associated silencing," 2020, Nature Genetics
  • "Reconstitution of the oocyte transcriptional network with transcription factors," 2020, Nature
  • "Limited rejuvenation of aged hematopoietic stem cells in young bone marrow niche," 2020, The Journal of Experimental Medicine
  • "Tet2 and Tet3 in B cells are required to repress CD86 and prevent autoimmunity," 2020, Nature Immunology
  • "ATF7-Dependent Epigenetic Changes Are Required for the Intergenerational Effect of a Paternal Low-Protein Diet," 2020, Molecular Cell

Frequent collaborators include:

  • Fumihito Miura
  • Hiromitsu Araki
  • Laure Ferry
  • Pierre-Antoine Defossez
  • Satoshi Okada

Best Publications

  • A comprehensive two-hybrid analysis to explore the yeast protein interactome

    Takashi Ito;Tomoko Chiba;Ritsuko Ozawa;Mikio Yoshida

  • Toward a protein–protein interaction map of the budding yeast: A comprehensive system to examine two-hybrid interactions in all possible combinations between the yeast proteins

    Takashi Ito;Kosuke Tashiro;Shigeru Muta;Ritsuko Ozawa

  • Amplification-free whole-genome bisulfite sequencing by post-bisulfite adaptor tagging

    Fumihito Miura;Yusuke Enomoto;Ryo Dairiki;Takashi Ito

  • Mouse oocyte methylomes at base resolution reveal genome-wide accumulation of non-CpG methylation and role of DNA methyltransferases.

    Kenjiro Shirane;Hidehiro Toh;Hisato Kobayashi;Fumihito Miura

  • Mechanism for phosphorylation-induced activation of the phagocyte NADPH oxidase protein p47(phox). Triple replacement of serines 303, 304, and 328 with aspartates disrupts the SH3 domain-mediated intramolecular interaction in p47(phox), thereby activating the oxidase.

    Tetsuro Ago;Hiroyuki Nunoi;Takashi Ito;Hideki Sumimoto

  • Fluorescent differential display : Arbitrarily primed RT-PCR fingerprinting on an automated DNA sequencer

    Takashi Ito;Keiji Kito;Naoki Adati;Yuko Mitsui

  • High-resolution DNA methylome analysis of primordial germ cells identifies gender-specific reprogramming in mice

    Hisato Kobayashi;Takayuki Sakurai;Fumihito Miura;Misaki Imai

  • A large-scale full-length cDNA analysis to explore the budding yeast transcriptome

    Fumihito Miura;Noriko Kawaguchi;Jun Sese;Atsushi Toyoda

  • Phosphorylation of p47phox directs phox homology domain from SH3 domain toward phosphoinositides, leading to phagocyte NADPH oxidase activation.

    Tetsuro Ago;Futoshi Kuribayashi;Hidekazu Hiroaki;Ryu Takeya

  • Assembly and Activation of the Phagocyte NADPH Oxidase SPECIFIC INTERACTION OF THE N-TERMINAL Src HOMOLOGY 3 DOMAIN OF p47phox WITH p22phox IS REQUIRED FOR ACTIVATION OF THE NADPH OXIDASE

    Hideki Sumimoto;Kenichiro Hata;Kazuhito Mizuki;Takashi Ito

  • Novel modular domain PB1 recognizes PC motif to mediate functional protein–protein interactions

    Takashi Ito;Yasushi Matsui;Tetsuro Ago;Kazuhisa Ota

  • Sequence-specific DNA purification by triplex affinity capture.

    Takashi Ito;Cassandra L. Smith;Charles R. Cantor

  • In Vivo Characterization of Bone Marrow–Derived Fibroblasts Recruited into Fibrotic Lesions

    Genichiro Ishii;Takafumi Sangai;Kenji Sugiyama;Takashi Ito;Takashi Ito

  • Structure and function of the PB1 domain, a protein interaction module conserved in animals, fungi, amoebas, and plants.

    Hideki Sumimoto;Sachiko Kamakura;Takashi Ito

  • Solution structure of the PX domain, a target of the SH3 domain.

    Hidekazu Hiroaki;Tetsuro Ago;Takashi Ito;Hideki Sumimoto

  • The adaptor protein p40phox as a positive regulator of the superoxide-producing phagocyte oxidase

    Futoshi Kuribayashi;Hiroyuki Nunoi;Kaori Wakamatsu;Shohko Tsunawaki

  • Podoplanin-Positive Fibroblasts Enhance Lung Adenocarcinoma Tumor Formation: Podoplanin in Fibroblast Functions for Tumor Progression

    Ayuko Hoshino;Genichiro Ishii;Takashi Ito;Kazuhiko Aoyagi

  • A comprehensive analysis of allelic methylation status of CpG islands on human chromosome 21q.

    Yoichi Yamada;Hidemi Watanabe;Fumihito Miura;Fumihito Miura;Hidenobu Soejima

  • Human homologues of the Caenorhabditis elegans cell polarity protein PAR6 as an adaptor that links the small GTPases Rac and Cdc42 to atypical protein kinase C.

    Yukiko Noda;Ryu Takeya;Shigeo Ohno;Seiji Naito

  • Crystal Structure of Aminopeptidase N (Proteobacteria Alanyl Aminopeptidase) from Escherichia coli and Conformational Change of Methionine 260 Involved in Substrate Recognition

    Kiyoshi Ito;Yoshitaka Nakajima;Yuko Onohara;Masahide Takeo

Frequent Co-Authors

Yoshiyuki Sakaki
Yoshiyuki Sakaki Toyohashi University of Technology
Hideki Sumimoto
Hideki Sumimoto Kyushu University
Yoshiyuki Sakaki
Yoshiyuki Sakaki Toyohashi University of Technology
Atsushi Ochiai
Atsushi Ochiai University of Tokyo
Masahira Hattori
Masahira Hattori Waseda University
Hiroshi Kimura
Hiroshi Kimura Tokyo Institute of Technology
Katsuhiko Shirahige
Katsuhiko Shirahige University of Tokyo
Tatsuhiro Shibata
Tatsuhiro Shibata University of Tokyo
Shinya Tanaka
Shinya Tanaka Hokkaido University
Yutaka Suzuki
Yutaka Suzuki University of Tokyo

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