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Katsuhiko Shirahige

Katsuhiko Shirahige

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Genetics and Molecular Biology
Japan
2024

D-Index & Metrics

Genetics

D-Index
91
Citations
27843
World Ranking
1045
National Ranking
38

Molecular Biology

D-Index
91
Citations
27843
World Ranking
723
National Ranking
53

Research.com Recognitions

  • 2024 - Research.com Genetics and Molecular Biology in Japan Leader Award

Overview

Katsuhiko Shirahige is affiliated with the University of Tokyo in Japan and specializes in the field of Biochemistry, Genetics, and Molecular Biology. Their research output primarily focuses on Molecular Biology, which encompasses a significant portion of their scholarly contributions.

The scientist's main topics of research include:

  • Genomics and Chromatin Dynamics
  • RNA Research and Splicing
  • DNA Repair Mechanisms
  • Epigenetics and DNA Methylation
  • RNA modifications and cancer
  • Ubiquitin and proteasome pathways
  • Chromosomal and Genetic Variations

Notable recent publications include:

  • "Tet2 and Tet3 in B cells are required to repress CD86 and prevent autoimmunity" (2020), published in Nature Immunology
  • "ATF7-Dependent Epigenetic Changes Are Required for the Intergenerational Effect of a Paternal Low-Protein Diet" (2020), published in Molecular Cell
  • "Small extracellular vesicles derived from interferon-γ pre-conditioned mesenchymal stromal cells effectively treat liver fibrosis" (2021), published in npj Regenerative Medicine
  • "Combined Cohesin-RUNX1 Deficiency Synergistically Perturbs Chromatin Looping and Causes Myelodysplastic Syndromes" (2020), published in Cancer Discovery
  • "Transcription-dependent cohesin repositioning rewires chromatin loops in cellular senescence" (2020), published in Nature Communications

Frequent co-authors collaborating with Shirahige include:

  • Ryuichiro Nakato
  • Toyonori Sakata
  • Masashige Bando
  • Katsunori Fujiki
  • Jiankang Wang

The scientist's work has been often published in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Zenodo (CERN European Organization for Nuclear Research)
  • Nature Communications
  • Molecular Cell
  • Gene

Best Publications

  • Cohesin mediates transcriptional insulation by CCCTC-binding factor

    Kerstin S. Wendt;Keisuke Yoshida;Takehiko Itoh;Masashige Bando

  • S-phase checkpoint proteins Tof1 and Mrc1 form a stable replication-pausing complex

    Yuki Katou;Yutaka Kanoh;Masashige Bando;Hideki Noguchi

  • Cohesin relocation from sites of chromosomal loading to places of convergent transcription

    Armelle Lengronne;Yuki Katou;Saori Mori;Saori Mori;Shihori Yokobayashi

  • HDAC8 mutations in Cornelia de Lange syndrome affect the cohesin acetylation cycle

    Matthew A. Deardorff;Masashige Bando;Ryuichiro Nakato;Erwan Watrin

  • Postreplicative recruitment of cohesin to double-strand breaks is required for DNA repair.

    Lena Ström;Hanna Betts Lindroos;Katsuhiko Shirahige;Camilla Sjögren

  • The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery

    Hendrik G. Stunnenberg;Martin Hirst

  • Protein phosphatase 2A protects centromeric sister chromatid cohesion during meiosis I

    Christian G Riedel;Vittorio L Katis;Vittorio L Katis;Yuki Katou;Saori Mori

  • Regulation of DNA-replication origins during cell-cycle progression.

    Katsuhiko Shirahige;Yuji Hori;Katsuya Shiraishi;Minoru Yamashita

  • The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line

    Harukazu Suzuki;Alistair R.R. Forrest;Erik Van Nimwegen;Carsten O. Daub

  • Sororin Mediates Sister Chromatid Cohesion by Antagonizing Wapl

    Tomoko Nishiyama;Rene Ladurner;Julia Schmitz;Emanuel Kreidl

  • Mutations in COQ2 in familial and sporadic multiple-system atrophy the multiple-system atrophy research collaboration

    Jun Mitsui;Takashi Matsukawa;Hiroyuki Ishiura;Yoko Fukuda;Yoko Fukuda

  • Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms

    Ayana Kon;Lee Yung Shih;Masashi Minamino;Masashi Sanada;Masashi Sanada

  • Postreplicative Formation of Cohesion Is Required for Repair and Induced by a Single DNA Break

    Lena Ström;Charlotte Karlsson;Charlotte Karlsson;Hanna Betts Lindroos;Hanna Betts Lindroos;Sara Wedahl;Sara Wedahl

  • Spo11-Accessory Proteins Link Double-Strand Break Sites to the Chromosome Axis in Early Meiotic Recombination

    Silvia Panizza;Marco A. Mendoza;Marc Berlinger;Lingzhi Huang

  • Identification of cis-acting sites for condensin loading onto budding yeast chromosomes

    Claudio D’Ambrosio;Christine Katrin Schmidt;Yuki Katou;Gavin Kelly

  • Evidence that Loading of Cohesin Onto Chromosomes Involves Opening of Its SMC Hinge

    Stephan Gruber;Prakash Arumugam;Yuki Katou;Daria Kuglitsch

  • Establishment of Sister Chromatid Cohesion at the S. cerevisiae Replication Fork

    Armelle Lengronne;Armelle Lengronne;John McIntyre;Yuki Katou;Yutaka Kanoh

  • PRDM14 ensures naive pluripotency through dual regulation of signaling and epigenetic pathways in mouse embryonic stem cells

    Masashi Yamaji;Jun Ueda;Katsuhiko Hayashi;Katsuhiko Hayashi;Hiroshi Ohta

  • Rif1 is a global regulator of timing of replication origin firing in fission yeast

    Motoshi Hayano;Yutaka Kanoh;Seiji Matsumoto;Claire Renard-Guillet

  • A mesodermal factor, T, specifies mouse germ cell fate by directly activating germline determinants

    Shinya Aramaki;Katsuhiko Hayashi;Kazuki Kurimoto;Hiroshi Ohta

Frequent Co-Authors

Takehiko Itoh
Takehiko Itoh Tokyo Institute of Technology
Ian D. Krantz
Ian D. Krantz Children's Hospital of Philadelphia
Hiroyuki Aburatani
Hiroyuki Aburatani University of Tokyo
Kim Nasmyth
Kim Nasmyth University of Oxford
Hiroshi Kimura
Hiroshi Kimura Tokyo Institute of Technology
Matthew A. Deardorff
Matthew A. Deardorff Children's Hospital of Philadelphia
Tetsu Akiyama
Tetsu Akiyama University of Tokyo
Shuichi Tsutsumi
Shuichi Tsutsumi University of Tokyo
Takashi Ito
Takashi Ito Kyushu University

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