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Shuichi Tsutsumi

Shuichi Tsutsumi

D-Index & Metrics

Molecular Biology

D-Index
55
Citations
11591
World Ranking
2268
National Ranking
177

Overview

Shuichi Tsutsumi is affiliated with the University of Tokyo in Japan and has contributed to multiple research areas primarily within biochemistry, genetics, and molecular biology, alongside medicine. Their work spans a number of subfields including molecular biology, cancer research, physiology, oncology, and pulmonary and respiratory medicine.

The scientist's research topics focus on various biological and medical themes:

  • Protein Degradation and Inhibitors
  • Adipose Tissue and Metabolism
  • Epigenetics and DNA Methylation
  • Cancer Genomics and Diagnostics
  • Lipid Metabolism and Biosynthesis
  • Histone Deacetylase Inhibitors Research
  • Adipokines, Inflammation, and Metabolic Diseases

Frequently published venues for their work include:

  • Cancer Research
  • Cancer Science
  • Nature Communications
  • The EMBO Journal
  • Blood

Shuichi Tsutsumi has several notable co-authors with whom collaboration has been frequent:

  • Hiroyuki Aburatani (18 publications)
  • Kenji Tatsuno (6 publications)
  • Kousuke Watanabe (6 publications)
  • Aya Shinozaki-Ushiku (6 publications)
  • Katsutoshi Oda (6 publications)

Among recent papers authored or co-authored by Shuichi Tsutsumi are:

  • "Coordinated demethylation of H3K9 and H3K27 is required for rapid inflammatory responses of endothelial cells," published in 2020 in The EMBO Journal
  • "Trib1 promotes acute myeloid leukemia progression by modulating the transcriptional programs of Hoxa9," published in 2020 in Blood
  • "Multi-omics analysis defines highly refractory RAS burdened immature subgroup of infant acute lymphoblastic leukemia," published in 2022 in Nature Communications
  • "NFIA differentially controls adipogenic and myogenic gene program through distinct pathways to ensure brown and beige adipocyte differentiation," published in 2020 in PLoS Genetics
  • "TET1 upregulation drives cancer cell growth through aberrant enhancer hydroxymethylation of HMGA2 in hepatocellular carcinoma," published in 2021 in Cancer Science

Best Publications

  • Cohesin mediates transcriptional insulation by CCCTC-binding factor

    Kerstin S. Wendt;Keisuke Yoshida;Takehiko Itoh;Masashige Bando

  • Global Gene Expression Analysis of Gastric Cancer by Oligonucleotide Microarrays

    Yoshitaka Hippo;Hirokazu Taniguchi;Shuichi Tsutsumi;Naoko Machida

  • Glucokinase and IRS-2 are required for compensatory β cell hyperplasia in response to high-fat diet–induced insulin resistance

    Yasuo Terauchi;Iseki Takamoto;Naoto Kubota;Junji Matsui

  • Differential gene expression profiles of scirrhous gastric cancer cells with high metastatic potential to peritoneum or lymph nodes.

    Yoshitaka Hippo;Masakazu Yashiro;Masami Ishii;Hirokazu Taniguchi

  • High-resolution characterization of a hepatocellular carcinoma genome

    Yasushi Totoki;Kenji Tatsuno;Shogo Yamamoto;Yasuhito Arai

  • Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues

    Xijin Ge;Shogo Yamamoto;Shuichi Tsutsumi;Yutaka Midorikawa

  • PH Domain-Only Protein PHLDA3 Is a p53-Regulated Repressor of Akt

    Tatsuya Kawase;Tatsuya Kawase;Rieko Ohki;Tatsuhiro Shibata;Shuichi Tsutsumi

  • Androgen-responsive long noncoding RNA CTBP1-AS promotes prostate cancer.

    Ken Ichi Takayama;Kuniko Horie-Inoue;Shintaro Katayama;Takashi Suzuki

  • The Peroxisome Proliferator-Activated Receptor γ/Retinoid X Receptor α Heterodimer Targets the Histone Modification Enzyme PR-Set7/Setd8 Gene and Regulates Adipogenesis through a Positive Feedback Loop

    Ken Ichi Wakabayashi;Masashi Okamura;Shuichi Tsutsumi;Naoko S. Nishikawa

  • ChIP-seq reveals cell type-specific binding patterns of BMP-specific Smads and a novel binding motif

    Masato Morikawa;Daizo Koinuma;Shuichi Tsutsumi;Eleftheria Vasilaki

  • Chromatin Immunoprecipitation on Microarray Analysis of Smad2/3 Binding Sites Reveals Roles of ETS1 and TFAP2A in Transforming Growth Factor β Signaling

    Daizo Koinuma;Shuichi Tsutsumi;Naoko Kamimura;Hirokazu Taniguchi

  • Dynamic change of chromatin conformation in response to hypoxia enhances the expression of GLUT3 (SLC2A3) by cooperative interaction of hypoxia-inducible factor 1 and KDM3A

    Imari Mimura;Masaomi Nangaku;Yasuharu Kanki;Shuichi Tsutsumi

  • Direct comparison of GeneChip and SAGE on the quantitative accuracy in transcript profiling analysis.

    Masami Ishii;Shin-ichi Hashimoto;Shuichi Tsutsumi;Yoichiro Wada

  • COUP-TFII acts downstream of Wnt/β-catenin signal to silence PPARγ gene expression and repress adipogenesis

    Masashi Okamura;Hiromi Kudo;Ken Ichi Wakabayashi;Toshiya Tanaka

  • Fish oil feeding alters liver gene expressions to defend against PPARα activation and ROS production

    Mayumi Takahashi;Nobuyo Tsuboyama-Kasaoka;Teruyo Nakatani;Masami Ishii

  • Architectural roles of multiple chromatin insulators at the human apolipoprotein gene cluster

    Tsuyoshi Mishiro;Tsuyoshi Mishiro;Ko Ishihara;Shinjiro Hino;Shuichi Tsutsumi

  • H3K4/H3K9me3 Bivalent Chromatin Domains Targeted by Lineage-Specific DNA Methylation Pauses Adipocyte Differentiation

    Yoshihiro Matsumura;Ryo Nakaki;Takeshi Inagaki;Ayano Yoshida

  • A wave of nascent transcription on activated human genes

    Youichiro Wada;Yoshihiro Ohta;Meng Xu;Shuichi Tsutsumi

  • Hepatocellular carcinoma in Txnip-deficient mice

    S S Sheth;J S Bodnar;A Ghazalpour;C K Thipphavong

  • Genome-Wide Profiling of the Core Clock Protein BMAL1 Targets Reveals a Strict Relationship with Metabolism

    Fumiyuki Hatanaka;Chiaki Matsubara;Jihwan Myung;Jihwan Myung;Jihwan Myung;Takashi Yoritaka

Frequent Co-Authors

Hiroyuki Aburatani
Hiroyuki Aburatani University of Tokyo
Tatsuhiko Kodama
Tatsuhiko Kodama University of Tokyo
Takao Hamakubo
Takao Hamakubo Nippon Medical School
Kohei Miyazono
Kohei Miyazono University of Tokyo
Katsuhiko Shirahige
Katsuhiko Shirahige University of Tokyo
Hiroshi Kimura
Hiroshi Kimura Tokyo Institute of Technology
Satoshi Inoue
Satoshi Inoue Saitama Medical University
Michitaka Hirose
Michitaka Hirose University of Tokyo
Juro Sakai
Juro Sakai University of Tokyo
Takashi Kadowaki
Takashi Kadowaki Toranomon Hospital

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