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Molecular Biology
UK
2026
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Genetics and Molecular Biology
UK
2024

D-Index & Metrics

Molecular Biology

D-Index
158
Citations
81932
World Ranking
70
National Ranking
4

Research.com Recognitions

  • 2026 - Research.com Molecular Biology in United Kingdom Leader Award
  • 2025 - Research.com Molecular Biology in United Kingdom Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in United Kingdom Leader Award
  • 2023 - Research.com Molecular Biology in United Kingdom Leader Award
  • 2018 - Breakthrough Prize in Life Sciences for elucidating the sophisticated mechanism that mediates the perilous separation of duplicated chromosomes during cell division and thereby prevents genetic diseases such as cancer.
  • 2007 - Canada Gairdner International Award
  • 1999 - Fellow of the American Academy of Arts and Sciences
  • 1999 - Wittgenstein Award
  • 1993 - Member of Academia Europaea
  • 1989 - Fellow of the Royal Society, United Kingdom
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Kim Nasmyth is affiliated with the University of Oxford in the United Kingdom. Their research primarily focuses on Biochemistry, Genetics, and Molecular Biology, with significant contributions to Molecular Biology, Plant Science, and Cell Biology. Their studies cover varied topics such as Genomics and Chromatin Dynamics, DNA Repair Mechanisms, Chromosomal and Genetic Variations, RNA Research and Splicing, DNA and Nucleic Acid Chemistry, Microtubule and mitosis dynamics, and Fungal and yeast genetics research.

Nasmyth's recent publications include these notable papers:

  • Cohesin Disrupts Polycomb-Dependent Chromosome Interactions in Embryonic Stem Cells (2020, Cell Reports)
  • Transport of DNA within cohesin involves clamping on top of engaged heads by Scc2 and entrapment within the ring by Scc3 (2020, eLife)
  • Cohesion is established during DNA replication utilising chromosome associated cohesin rings as well as those loaded de novo onto nascent DNAs (2020, eLife)
  • Analysis of Genome Architecture during SCNT Reveals a Role of Cohesin in Impeding Minor ZGA (2020, Molecular Cell)
  • Folding of cohesin's coiled coil is important for Scc2/4-induced association with chromosomes (2021, eLife)

The scientist frequently collaborates with several co-authors, including Naomi J Petela, Menelaos Voulgaris, Byung-Gil Lee, Jan Löwe, and James Collier. Their work is often published in venues such as bioRxiv (Cold Spring Harbor Laboratory), eLife, Science, Cell Reports, and Molecular Cell.

Nasmyth has been recognized with multiple awards for contributions to the scientific community. Among them are the Breakthrough Prize in Life Sciences in 2018 for work elucidating the mechanism of chromosome separation during cell division, the Canada Gairdner International Award in 2007, and fellowships including Fellow of the American Academy of Arts and Sciences (1999), Fellow of the Royal Society, United Kingdom (1989), and fellowships or memberships in prestigious organizations such as the Academy of Medical Sciences, United Kingdom and the European Molecular Biology Organization (EMBO).

Best Publications

  • Cohesins: chromosomal proteins that prevent premature separation of sister chromatids

    Christine Michaelis;Rafal Ciosk;Kim Nasmyth

  • Sister-chromatid separation at anaphase onset is promoted by cleavage of the cohesin subunit Scc1

    Frank Uhlmann;Friedrich Lottspeich;Kim Nasmyth

  • The B-type cyclin kinase inhibitor p40SIC1 controls the G1 to S transition in S. cerevisiae

    Etienne Schwob;Thomas Böhm;Michael D. Mendenhall;Kim Nasmyth

  • Cohesin: Its Roles and Mechanisms

    Kim Nasmyth;Christian H. Haering

  • Genetic control of the cell division cycle in the fission yeast Schizosaccharomyces pombe

    Paul Nurse;Paul Nurse;Pierre Thuriaux;Pierre Thuriaux;Kim Nasmyth;Kim Nasmyth

  • Epitope tagging of yeast genes using a PCR‐based strategy: more tags and improved practical routines

    Michael Knop;Katja Siegers;Gislene Pereira;Wolfgang Zachariae

  • Cleavage of Cohesin by the CD Clan Protease Separin Triggers Anaphase in Yeast

    Frank Uhlmann;Dominik Wernic;Marc André Poupart;Eugene V. Koonin

  • Disseminating the Genome: Joining, Resolving, and Separating Sister Chromatids During Mitosis and Meiosis

    Kim Nasmyth

  • Whose end is destruction: cell division and the anaphase-promoting complex.

    Wolfgang Zachariae;Kim Nasmyth

  • Evidence that the Ipl1-Sli15 (Aurora Kinase-INCENP) Complex Promotes Chromosome Bi-orientation by Altering Kinetochore-Spindle Pole Connections

    Tomoyuki U. Tanaka;Tomoyuki U. Tanaka;Najma Rachidi;Carsten Janke;Gislene Pereira

  • Ordered Recruitment of Transcription and Chromatin Remodeling Factors to a Cell Cycle- And Developmentally Regulated Promoter

    Maria Pia Cosma;Tomoyuki Tanaka;Kim Nasmyth

  • Molecular Architecture of SMC Proteins and the Yeast Cohesin Complex

    Christian H. Haering;Jan Löwe;Andreas Hochwagen;Kim Nasmyth

  • An ESP1/PDS1 Complex Regulates Loss of Sister Chromatid Cohesion at the Metaphase to Anaphase Transition in Yeast

    Rafal Ciosk;Wolfgang Zachariae;Christine Michaelis;Andrej Shevchenko

  • Cohesin's Binding to Chromosomes Depends on a Separate Complex Consisting of Scc2 and Scc4 Proteins

    Rafal Ciosk;Masaki Shirayama;Anna Shevchenko;Tomoyuki Tanaka

  • A central role for cohesins in sister chromatid cohesion, formation of axial elements, and recombination during yeast meiosis.

    Franz Klein;Peter Mahr;Marta Galova;Sara B.C. Buonomo

  • Un ménage à quatre: the molecular biology of chromosome segregation in meiosis.

    Mark Petronczki;Maria F Siomos;Kim Nasmyth

  • THE STRUCTURE AND FUNCTION OF SMC AND KLEISIN COMPLEXES

    Kim Nasmyth;Christian H. Haering

  • Segregating sister genomes: the molecular biology of chromosome separation.

    Kim Nasmyth

  • Chromosomal Cohesin Forms a Ring

    Stephan Gruber;Christian H Haering;Kim Nasmyth

  • The B-type cyclin kinase inhibitor p40(SiC1) Controls the G1 to S transition in S-cerevisiae (vol 79, pg 233, 1994)

    E Schwob;T Bohm;Mendenhall;K Nasmyth

Frequent Co-Authors

Alexander Schleiffer
Alexander Schleiffer Research Institute of Molecular Pathology
Frank Uhlmann
Frank Uhlmann The Francis Crick Institute
Jan Löwe
Jan Löwe MRC Laboratory of Molecular Biology
Jan-Michael Peters
Jan-Michael Peters Research Institute of Molecular Pathology
Katsuhiko Shirahige
Katsuhiko Shirahige University of Tokyo
Karl Mechtler
Karl Mechtler Research Institute of Molecular Pathology
Bela Novak
Bela Novak University of Oxford
Benjamin D. Hall
Benjamin D. Hall University of Washington
David J. Stillman
David J. Stillman University of Utah

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