2015 - Fellow of the Royal Society, United Kingdom
Member of the European Molecular Biology Organization (EMBO)
Separase, Cohesin, Anaphase, Establishment of sister chromatid cohesion and Cell biology are his primary areas of study. His work deals with themes such as DNA replication and Cohesin complex, which intersect with Separase. His Cohesin study is concerned with Genetics in general.
His Anaphase research is multidisciplinary, relying on both Spindle apparatus and Metaphase. His study looks at the intersection of Establishment of sister chromatid cohesion and topics like Cohesin loading with Control of chromosome duplication and Origin recognition complex. The study incorporates disciplines such as Molecular biology, Securin and Mitotic exit in addition to Cell biology.
His primary areas of study are Cell biology, Cohesin, Genetics, Establishment of sister chromatid cohesion and Separase. Frank Uhlmann combines subjects such as Chromatin, Cyclin-dependent kinase and Mitotic exit, Anaphase with his study of Cell biology. His Anaphase research includes elements of Metaphase and Spindle checkpoint.
His studies in Cohesin integrate themes in fields like Sister chromatids and Chromosome segregation. His research investigates the connection between Establishment of sister chromatid cohesion and topics such as DNA replication that intersect with issues in Molecular biology. His Separase study combines topics from a wide range of disciplines, such as Securin and Biochemical switches in the cell cycle.
His primary areas of investigation include Cell biology, Cohesin, DNA, Establishment of sister chromatid cohesion and Chromatin. His Cell biology study combines topics in areas such as Genetics, Mitotic exit and Cell cycle. His works in Separase and Cell division are all subjects of inquiry into Genetics.
His Cohesin complex and Cohesin loading study in the realm of Cohesin interacts with subjects such as Accession. The Establishment of sister chromatid cohesion study combines topics in areas such as DNA repair and DNA replication. His Chromosome segregation research incorporates elements of Plasma protein binding and Sister chromatids.
Frank Uhlmann focuses on Cell biology, Cohesin, Establishment of sister chromatid cohesion, Cohesin complex and Genetics. His Cell biology research incorporates themes from Chromatin and Mitotic chromosome condensation. His research in Cohesin is mostly concerned with Cohesin loading.
His Establishment of sister chromatid cohesion study is concerned with the larger field of Chromosome segregation. His work deals with themes such as Centromere, SMC protein, Sister chromatids and Kinetochore, which intersect with Chromosome segregation. Frank Uhlmann has researched Cohesin complex in several fields, including Replisome, GINS, DNA replication and Chromatid.
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Sister-chromatid separation at anaphase onset is promoted by cleavage of the cohesin subunit Scc1
Frank Uhlmann;Friedrich Lottspeich;Kim Nasmyth.
Nature (1999)
Cleavage of Cohesin by the CD Clan Protease Separin Triggers Anaphase in Yeast
Frank Uhlmann;Dominik Wernic;Marc-André Poupart;Eugene V Koonin.
Cell (2000)
Yeast cohesin complex requires a conserved protein, Eco1p(Ctf7), to establish cohesion between sister chromatids during DNA replication.
Attila Tóth;Rafal Ciosk;Frank Uhlmann;Marta Galova.
Genes & Development (1999)
Cohesion between sister chromatids must be established during DNA replication
Frank Uhlmann;Kim Nasmyth.
Current Biology (1998)
Eco1-Dependent Cohesin Acetylation During Establishment of Sister Chromatid Cohesion
Tom Rolef Ben-Shahar;Sebastian Heeger;Chris Lehane;Philip East.
Science (2008)
Cohesin relocation from sites of chromosomal loading to places of convergent transcription
Armelle Lengronne;Yuki Katou;Saori Mori;Saori Mori;Shihori Yokobayashi.
Nature (2004)
Disjunction of Homologous Chromosomes in Meiosis I Depends on Proteolytic Cleavage of the Meiotic Cohesin Rec8 by Separin
Sara B.C Buonomo;Rosemary K Clyne;Joerg Fuchs;Josef Loidl.
Cell (2000)
Splitting the chromosome: cutting the ties that bind sister chromatids.
Nasmyth K;Peters Jm;Uhlmann F.
Science (2000)
Phosphorylation of the Cohesin Subunit Scc1 by Polo/Cdc5 Kinase Regulates Sister Chromatid Separation in Yeast
Gabriela Alexandru;Frank Uhlmann;Karl Mechtler;Marc-André Poupart.
Cell (2001)
SMC complexes: from DNA to chromosomes
Frank Uhlmann.
Nature Reviews Molecular Cell Biology (2016)
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